Cancer Institute of New Jersey (CINJ), Division of Surgical Oncology, Melanoma & Soft Tissue Oncology

Research Output

2018

Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo

Chen, H. C., Sierra, J., Yu, L. J., Cerchio, R., Wall, B. A. & Chen, S., 2018, In : Oncotarget. 9, 5, p. 5861-5875 15 p.

Rutgers, The State University

Research output: Contribution to journalArticle

2 Scopus citations

A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in patients with advanced melanoma

Mehnert, J. M., Silk, A. W., Lee, J. H., Dudek, L., Jeong, B. S., Li, J., Schenkel, J. M., Sadimin, E., Kane, M., Lin, H., Shih, W. J. & Chen, S., Jul 2018, In : Pigment Cell and Melanoma Research. 31, 4, p. 534-540 7 p.

Rutgers, The State University

Research output: Contribution to journalArticle

9 Scopus citations

Exosomes released by metabotropic glutamate receptor 1 (GRM1) expressing melanoma cells increase cell migration and invasiveness

Isola, A. L., Eddy, K., Zembrzuski, K. & Chen, S., 2018, In : Oncotarget. 9, 1, p. 1187-1199 13 p.

Rutgers, The State University

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo

Shin, S. S., Jeong, B. S., Wall, B. A., Li, J., Shan, N. L., Wen, Y. & Chen, S., Nov 1 2018, In : Oncogenesis. 7, 11, 86.

Rutgers, The State University

Research output: Contribution to journalArticle

2 Scopus citations
2017
3 Scopus citations
2016

Acral lentiginous melanoma

Shoen, S. L., Jan 1 2016, Cancer Treatment and Research. Kluwer Academic Publishers, p. 321-329 9 p. (Cancer Treatment and Research; vol. 167).

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Scopus citations

Final Results of the Sunbelt Melanoma trial: A multi-institutional prospective randomized phase III study evaluating the role of adjuvant high-dose interferon alfa-2b and completion lymph node dissection for patients staged by sentinel lymph node biopsy

McMasters, K. M., Egger, M. E., Edwards, M. J., Ross, M. I., Reintgen, D. S., Noyes, R. D., Martin, R. C. G., Beitsch, P. D., Urist, M. M., Ariyan, S., Sussman, J. J., Davidson, B. S., Gershenwald, J. E., Hagendoorn, L. J., Stromberg, A. J. & Scoggins, C. R., Apr 1 2016, In : Journal of Clinical Oncology. 34, 10, p. 1079-1086 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

39 Scopus citations

Letters

Day, A. K., Stapleton, J. L., Manne, S. L., Tatum, K. L. & Coups, E. J., Feb 2016, In : JAMA dermatology. 152, 2, p. 213-215 3 p.

Rutgers, The State University

Research output: Contribution to journalLetter

1 Scopus citations

Recurrent Nevi in a Skin Graft Following Excision of Giant Congenital Melanocytic Nevus

Criscito, M. C., Correa, L. M., Koshenkov, V. & Firoz, B. F., Sep 1 2016, In : Dermatologic Surgery. 42, 9, p. 1113-1116 4 p.

Rutgers, The State University

Research output: Contribution to journalShort survey

1 Scopus citations

Skin self-examination behaviors among individuals diagnosed with melanoma

Coups, E. J., Manne, S. L., Stapleton, J. L. & Tatum, K. L., Jan 1 2016, In : Melanoma Research. 26, 1, p. 71-76 6 p.

Rutgers, The State University

Research output: Contribution to journalArticle

21 Scopus citations

Surgical management of melanoma

Koshenkov, V. P., Broucek, J. & Kaufman, H. L., Jan 1 2016, Cancer Treatment and Research. Kluwer Academic Publishers, p. 149-179 31 p. (Cancer Treatment and Research; vol. 167).

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma

Boregowda, R. K., Medina, D. J., Markert, E., Bryan, M. A., Chen, W., Chen, S., Rabkin, A., Vido, M. J., Gunderson, S. I., Chekmareva, M., Foran, D. J., Lasfar, A. & Cohen-Solal, K. A., May 17 2016, In : Oncotarget. 7, 20, p. 29689-29707 19 p.

Rutgers, The State University

Research output: Contribution to journalArticle

9 Scopus citations
2015

Nutritional support

Melstrom, L. G., Koshenkov, V. & August, D., Jan 7 2015, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology: Tenth Edition. Wolters Kluwer Health Adis (ESP)

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations
6 Scopus citations

Targeting glutamatergic signaling and the PI3 kinase pathway to halt melanoma progression

Rosenberg, S. A., Niglio, S. A., Salehomoum, N., Chan, J. L. K., Jeong, B. S., Wen, Y., Li, J., Fukui, J., Chen, S. & Shin, S. S., Jan 1 2015, In : Translational Oncology. 8, 1, p. 1-9 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

12 Scopus citations
2014

Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression

Wen, Y., Li, J., Koo, J., Shin, S. S., Lin, Y., Jeong, B. S., Mehnert, J. M., Chen, S. & Cohen-Sola, K. A., Jan 5 2014, In : Cancer Research. 74, 9, p. 2499-2509 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

26 Scopus citations
8 Scopus citations

Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells

Wall, B. A., Wangari-Talbot, J., Shin, S. S., Schiff, D., Sierra, J., Yu, L. J., Haffty, B. & Chen, S., Mar 1 2014, In : Pigment Cell and Melanoma Research. 27, 2, p. 263-274 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

14 Scopus citations

Epac1 increases migration of endothelial cells and melanoma cells via FGF2-mediated paracrine signaling

Baljinnyam, E., Umemura, M., Chuang, C., De Lorenzo, M. S., Iwatsubo, M., Chen, S., Ishikawa, Y., Whitelock, J. M. & Iwatsubo, K., Jul 2014, In : Pigment Cell and Melanoma Research. 27, 4, p. 611-620 10 p.

Rutgers, The State University

Research output: Contribution to journalArticle

17 Scopus citations

Interdigitating dendritic cell sarcoma presenting in the skin: Diagnosis and the role of surgical resection, chemotherapy and radiotherapy in management

Rosenberg, S. A., Niglio, S. A. & Jo, V. Y., Sep 3 2014, In : Rare Tumors. 6, 4, p. 135-137 3 p., 5573.

Rutgers, The State University

Research output: Contribution to journalArticle

6 Scopus citations

Malignancy

Melstrom, L. G., Koshenkov, V. & August, D., Jan 1 2014, Surgical Metabolism: The Metabolic Care of the Surgical Patient. Springer New York, p. 147-166 20 p.

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabotropic glutamate receptor-1 contributes to progression in triple negative breast cancer

Banda, M., Speyer, C. L., Semma, S. N., Osuala, K. O., Kounalakis, N., Torres, K. E. T., Barnard, N. J., Kim, H. J., Sloane, B. F., Miller, F. R. & Gorski, D. H., Jan 3 2014, In : PLoS ONE. 9, 1, e81126.

Rutgers, The State University

Research output: Contribution to journalArticle

22 Scopus citations
8 Scopus citations

Psychosocial correlates of sun protection behaviors among U.S. Hispanic adults

Coups, E. J., Stapleton, J. L., Manne, S. L., Hudson, S. V., Medina-Forrester, A., Rosenberg, S. A., Gordon, M., Tatum, K. S., Robinson, J. K. & Natale-Pereira, A., Jan 1 2014, In : Journal of behavioral medicine. 37, 6, p. 1082-1090 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

21 Scopus citations

RUNX2 is overexpressed in melanoma cells and mediates their migration and invasion

Boregowda, R. K., Olabisi, O. O., Abushahba, W., Jeong, B. S., Haenssen, K. K., Chen, W., Chekmareva, M., Lasfar, A., Foran, D. J. & Cohen-Solal, K. A., Jan 1 2014, In : Cancer Letters. 348, 1-2, p. 61-70 10 p.

Rutgers, The State University

Research output: Contribution to journalArticle

22 Scopus citations

Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migration

Umemura, M., Baljinnyam, E., Feske, S., De Lorenzo, M. S., Xie, L. H., Feng, X., Oda, K., Makino, A., Fujita, T., Yokoyama, U., Iwatsubo, M., Chen, S., Ishikawa, Y. & Iwatsubo, K., Feb 21 2014, In : PLoS ONE. 9, 2, e89292.

Rutgers, The State University

Research output: Contribution to journalArticle

88 Scopus citations

Tracheobronchial injury in the setting of an esophagectomy for cancer: Postoperative discovery a bad omen

Koshenkov, V. P., Yakoub, D., Livingstone, A. S. & Franceschi, D., Jun 2014, In : Journal of Surgical Oncology. 109, 8, p. 804-807 4 p.

Rutgers, The State University

Research output: Contribution to journalReview article

5 Scopus citations
2013

Linguistic acculturation and skin cancer-related behaviors among hispanics in the southern and western united states

Coups, E. J., Stapleton, J. L., Hudson, S. V., Medina-Forrester, A., Rosenberg, S. A., Gordon, M. A. & Natale-Pereira, A., Jun 1 2013, In : JAMA dermatology. 149, 6, p. 679-686 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

26 Scopus citations

Skin cancer surveillance behaviors among US Hispanic adults

Coups, E. J., Stapleton, J. L., Hudson, S. V., Medina-Forrester, A., Rosenberg, S. A., Gordon, M. & Natale-Pereira, A., Jan 1 2013, In : Journal of the American Academy of Dermatology. 68, 4, p. 576-584 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

20 Scopus citations
2012

Functional effects of GRM1 suppression in human melanoma cells

Wangari-Talbot, J., Wall, B. A. & Chen, S., Nov 1 2012, In : Molecular Cancer Research. 10, 11, p. 1440-1450 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

25 Scopus citations
6 Scopus citations

MDM4 is a key therapeutic target in cutaneous melanoma

Gembarska, A., Luciani, F., Fedele, C., Russell, E. A., Dewaele, M., Villar, S., Zwolinska, A., Haupt, S., De Lange, J., Yip, D., Haigh, J. J., Haupt, Y., Larue, L., Jochemsen, A., Shi, H., Moriceau, G., Lo, R. S., Ghanem, G., Shackleton, M., Bernal, F. & 1 others, Marine, J. C., Aug 1 2012, In : Nature medicine. 18, 8, p. 1239-1247 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

179 Scopus citations

Non-Canonical Smads Phosphorylation Induced by the Glutamate Release Inhibitor, Riluzole, through GSK3 Activation in Melanoma

Abushahba, W., Olabisi, O. O., Jeong, B. S., Boregowda, R. K., Wen, Y., Liu, F., Lasfar, A. & Cohen-Solal, K. A., Oct 12 2012, In : PLoS ONE. 7, 10, e47312.

Rutgers, The State University

Research output: Contribution to journalArticle

11 Scopus citations

Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration

Ochoa-Alvarez, J. A., Krishnan, H., Shen, Y., Acharya, N. K., Han, M., McNulty, D. E., Hasegawa, H., Hyodo, T., Senga, T., Geng, J. G., Kosciuk, M., Shin, S. S., Goydos, J. S., Temiakov, D., Nagele, R. G. & Goldberg, G. S., Jul 23 2012, In : PLoS ONE. 7, 7, e41845.

Rowan University, Rutgers, The State University

Research output: Contribution to journalArticle

40 Scopus citations
28 Scopus citations
2011

Constitutive Smad linker phosphorylation in melanoma: A mechanism of resistance to transforming growth factor-β-mediated growth inhibition

Cohen-Solal, K. A., Merrigan, K. T., Chan, J. L. K., Chen, W., Foran, D. J., Liu, F., Lasfar, A. & Reiss, M., Jun 1 2011, In : Pigment Cell and Melanoma Research. 24, 3, p. 512-524 13 p.

Rutgers, The State University

Research output: Contribution to journalArticle

19 Scopus citations

Epac1 promotes melanoma metastasis via modification of heparan sulfate

Baljinnyam, E., Umemura, M., De Lorenzo, M. S., Iwatsubo, M., Chen, S. & Iwatsubo, K., Aug 1 2011, In : Pigment Cell and Melanoma Research. 24, 4, p. 680-687 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

16 Scopus citations

Glutamatergic pathway targeting in melanoma: Single-agent and combinatorial therapies

Lee, H. J., Wall, B. A., Wangari-Talbot, J., Shin, S. S., Rosenberg, S., Chan, J. L. K., Namkoong, J. & Chen, S., Nov 15 2011, In : Clinical Cancer Research. 17, 22, p. 7080-7092 13 p.

Rutgers, The State University

Research output: Contribution to journalArticle

44 Scopus citations

Gβγ subunits inhibit Epac-induced melanoma cell migration

Baljinnyam, E., Umemura, M., De Lorenzo, M. S., Xie, L. H., Nowycky, M., Iwatsubo, M., Chen, S. & Iwatsubo, K., Jun 17 2011, In : BMC Cancer. 11, 256.

Rutgers, The State University

Research output: Contribution to journalArticle

9 Scopus citations

Molecular analysis of melanoma-induced sentinel lymph node immune dysfunction

Lee, J. H., Chen, Y., Chan, J. L. & Qian, Y. W., May 1 2011, In : Cancer Immunology, Immunotherapy. 60, 5, p. 685-692 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

13 Scopus citations
29 Scopus citations
2010

AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1)

Shin, S. S., Wall, B. A. & Chen, S., Feb 1 2010, In : Pigment Cell and Melanoma Research. 23, 1, p. 103-111 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

32 Scopus citations

c-Jun regulates phosphoinositide-dependent kinase 1 transcription: Implication for Akt and protein kinase C activities melanoma tumorigenesis

Lopez-Bergami, P., Kim, H., Dewing, A., Aaronson, S. & Ronai, Z., 2010, In : Journal of Biological Chemistry. 285, 2, p. 903-913 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

34 Scopus citations

Exchange protein directly activated by cyclic AMP increases melanoma cell migration by a Ca2+-dependent mechanism

Baljinnyam, E., De Lorenzo, M. S., Xie, L. H., Iwatsubo, M., Chen, S., Nowycky, M. C. & Iwatsubo, K., Jul 1 2010, In : Cancer Research. 70, 13, p. 5607-5617 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

43 Scopus citations

Factors associated with false-negative sentinel lymph node biopsy in melanoma patients

Scoggins, C. R., Martin, R. C. G., Ross, M. I., Edwards, M. J., Reintgen, D. S., Urist, M. M., Gershenwald, J. E., Sussman, J. J., Dirk Noyes, R., Beitsch, P. D., Ariyan, S., Stromberg, A. J., Hagendoorn, L. J. & McMasters, K. M., Mar 1 2010, In : Annals of Surgical Oncology. 17, 3, p. 709-717 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

75 Scopus citations

GLI2-mediated melanoma invasion and metastasis

Alexaki, V. I., Javelaud, D., Van Kempen, L. C. L., Mohammad, K. S., Dennler, S., Luciani, F., Hoek, K. S., Jurez, P., Fournier, P. J., Sibon, C., Bertolotto, C., Verrecchia, F., Saule, S., Delmas, V., Ballotti, R., Larue, L., Saiag, P., Guise, T. A. & Mauviel, A., Aug 4 2010, In : Journal of the National Cancer Institute. 102, 15, p. 1148-1159 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

118 Scopus citations

Role of the G protein-coupled receptor, mGlu1, in melanoma development

Wangari-Talbot, J. & Chen, S., 2010, In : Pharmaceuticals. 3, 9, p. 2821-2837 17 p.

Rutgers, The State University

Research output: Contribution to journalReview article

2 Scopus citations