Cell Biology

Research Output 1979 2019

2019

AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving

Murray, C. H., Loweth, J., Milovanovic, M., Stefanik, M. T., Caccamise, A. J., Dolubizno, H., Funke, J. R., Foster Olive, M. & Wolf, M. E., Aug 1 2019, In : Neuropsychopharmacology. 44, 9, p. 1534-1541 8 p.

Rowan University

Research output: Contribution to journalArticle

AMPA Receptors
Methamphetamine
Nucleus Accumbens
Cocaine
Synapses
1 Citation (Scopus)

Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations (Nature, (2016), 540, 7632, (270-275), 10.1038/nature20592)

Kang, E., Wu, J., Gutierrez, N. M., Koski, A., Tippner-Hedges, R., Agaronyan, K., Platero-Luengo, A., Martinez-Redondo, P., Ma, H., Lee, Y., Hayama, T., Van Dyken, C., Wang, X., Luo, S., Ahmed, R., Li, Y., Ji, D., Kayali, R., Cinnioglu, C., Olson, S. & 10 others, Jensen, J., Battaglia, D., Lee, D., Wu, D., Huang, T., Wolf, D. P., Temiakov, D., Belmonte, J. C. I., Amato, P. & Mitalipov, S., Mar 14 2019, In : Nature. 567, 7747, p. E5-E9

Rowan University

Research output: Contribution to journalComment/debate

Open Access
Mitochondrial DNA
Haplotypes
Oocytes
Ovum
History
1 Citation (Scopus)
Locus Coeruleus
Performance-Enhancing Substances
Norepinephrine
Attention Deficit Disorder with Hyperactivity
Norepinephrine Plasma Membrane Transport Proteins
2 Citations (Scopus)

mGlu1 tonically regulates levels of calcium-permeable AMPA receptors in cultured nucleus accumbens neurons through retinoic acid signaling and protein translation

Loweth, J., Reimers, J. M., Caccamise, A., Stefanik, M. T., Woo, K. K. Y., Chauhan, N. M., Werner, C. T. & Wolf, M. E., Aug 1 2019, In : European Journal of Neuroscience. 50, 3, p. 2590-2601 12 p.

Rowan University

Research output: Contribution to journalArticle

AMPA Receptors
Nucleus Accumbens
Protein Biosynthesis
Tretinoin
Calcium

Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia

Osypenko, D. S., Dovgan, A. V., Kononenko, N. I., Dromaretsky, A. V., Matvieienko, M., Rybachuk, O. A., Zhang, J., Korogod, S. M., Venkataraman, V. & Belan, P., Dec 2019, In : Neurobiology of Disease. 132, 104529.

Rowan University

Research output: Contribution to journalArticle

Hippocalcin
Dystonia
Neuronal Calcium-Sensor Proteins
Theta Rhythm
Dystonic Disorders

Reply to: Reversion after replacement of mitochondrial DNA

Kang, E., Koski, A., Amato, P., Temiakov, D. & Mitalipov, S., Oct 17 2019, In : Nature. 574, 7778, p. E12-E13

Rowan University

Research output: Contribution to journalLetter

Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention

Marshall, C. A., Brodnik, Z. D., Mortensen, O. V., Reith, M. E. A., Shumsky, J. S., Waterhouse, B., España, R. A. & Kortagere, S., Apr 1 2019, In : Neuropharmacology. 148, p. 178-188 11 p.

Rowan University

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
Dopamine D3 Receptors
Norepinephrine
Dopamine
Methylphenidate
1 Citation (Scopus)

Selective D2 and D3 receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens

Manvich, D., Petko, A. K., Branco, R. C., Foster, S. L., Porter-Stransky, K. A., Stout, K. A., Newman, A. H., Miller, G. W., Paladini, C. A. & Weinshenker, D., Jul 1 2019, In : Neuropsychopharmacology. 44, 8, p. 1445-1455 11 p.

Rowan University

Research output: Contribution to journalArticle

Nucleus Accumbens
Cocaine
Dopamine
Synaptic Transmission
3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole
Corticosterone
Prefrontal Cortex
Geniculate Bodies
Glucocorticoids
Serotonin
3 Citations (Scopus)

The locus coeruleus-norepinephrine system and sensory signal processing: A historical review and current perspectives

Waterhouse, B. & Navarra, R. L., Apr 15 2019, In : Brain research. 1709, p. 1-15 15 p.

Rowan University

Research output: Contribution to journalReview article

Locus Coeruleus
Norepinephrine
Brain Stem
Decision Making
Neurons

Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation

Jones, J. L., Hofmann, K. B., Cowan, A. T., Temiakov, D., Cramer, P. & Anikin, M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 18, p. 7528-7536 9 p.

Rowan University

Research output: Contribution to journalArticle

Fungal Proteins
Mitochondrial Proteins
Genes
Chemical activation
Messenger RNA
2018
5 Citations (Scopus)

Acetylation and phosphorylation of human TFAM regulate TFAM-DNA interactions via contrasting mechanisms

King, G. A., Hashemi Shabestari, M., Taris, K. K. H., Pandey, A. K., Venkatesh, S., Thilagavathi, J., Singh, K., Krishna Koppisetti, R., Temiakov, D., Roos, W. H., Suzuki, C. K. & Wuite, G. J. L., Apr 20 2018, In : Nucleic acids research. 46, 7, p. 3633-3642 10 p.

Rutgers, The State University, Rowan University

Research output: Contribution to journalArticle

Open Access
Acetylation
Phosphoserine
Phosphorylation
Mitochondrial DNA
DNA
10 Citations (Scopus)

Acute Stress Persistently Alters Locus Coeruleus Function and Anxiety-like Behavior in Adolescent Rats

Borodovitsyna, O., Flamini, M. D. & Chandler, D., Mar 1 2018, In : Neuroscience. 373, p. 7-19 13 p.

Rowan University

Research output: Contribution to journalArticle

Adolescent Behavior
Locus Coeruleus
Anxiety
Neurons
Physical Restraint
4 Citations (Scopus)

Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels

Di Ciano, P., Manvich, D., Pushparaj, A., Gappasov, A., Hess, E. J., Weinshenker, D. & Le Foll, B., Jan 1 2018, In : Psychopharmacology. 235, 1, p. 23-35 13 p.

Rowan University

Research output: Contribution to journalArticle

Choice Behavior
Disulfiram
Gambling
Catecholamines
Rodentia
3 Citations (Scopus)

Escherichia coli ItaT is a type II toxin that inhibits translation by acetylating isoleucyl-tRNAIle

Wilcox, B., Osterman, I., Serebryakova, M., Lukyanov, D., Komarova, E., Gollan, B., Morozova, N., Wolf, Y. I., Makarova, K. S., Helaine, S., Sergiev, P., Dubiley, S., Borukhov, S. & Severinov, K., Jan 1 2018, In : Nucleic acids research. 46, 15, p. 7873-7885 13 p.

Rutgers, The State University, Rowan University

Research output: Contribution to journalArticle

RNA, Transfer, Ile
Antitoxins
Escherichia coli
Acetyltransferases
Transfer RNA
1 Citation (Scopus)

Highly efficient 5’ capping of mitochondrial RNA with nad + and NADH by yeast and human mitochondrial RNA polymerase

Bird, J. G., Basu, U., Kuster, D., Ramachandran, A., Grudzien-Nogalska, E., Towheed, A., Wallace, D. C., Kiledjian, M., Temiakov, D., Patel, S., Ebright, R. & Nickels, B., Dec 1 2018, In : eLife. 7, e42179.

Rutgers, The State University, Rowan University

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
NAD
Yeast
Yeasts
RNA Caps
1 Citation (Scopus)

Iron-dependent cleavage of ribosomal RNA during oxidative stress in the yeast Saccharomyces cerevisiae

Zinskie, J. A., Ghosh, A., Trainor, B. M., Shedlovskiy, D., Pestov, D. & Shcherbik, N., Jan 1 2018, In : Journal of Biological Chemistry. 293, 37, p. 14237-14248 12 p.

Rowan University

Research output: Contribution to journalArticle

Oxidative stress
Ribosomal RNA
Yeast
Saccharomyces cerevisiae
Ribosomes
5 Citations (Scopus)

Persistent stress-induced neuroplastic changes in the locus coeruleus/norepinephrine system

Borodovitsyna, O., Joshi, N. & Chandler, D., Jan 1 2018, In : Neural Plasticity. 2018, 1892570.

Rowan University

Research output: Contribution to journalReview article

Locus Coeruleus
Norepinephrine
Neurons
Neuronal Plasticity
AMPA Receptors
7 Citations (Scopus)

Repeated restraint stress exposure during early withdrawal accelerates incubation of cue-induced cocaine craving

Glynn, R. M., Rosenkranz, J. A., Wolf, M. E., Caccamise, A., Shroff, F., Smith, A. B. & Loweth, J., Jan 1 2018, In : Addiction Biology. 23, 1, p. 80-89 10 p.

Rowan University

Research output: Contribution to journalArticle

Cocaine
Cues
Recurrence
Food Deprivation
Cocaine-Related Disorders
2 Citations (Scopus)

Structural basis of mitochondrial transcription

Hillen, H. S., Temiakov, D. & Cramer, P., Sep 1 2018, In : Nature Structural and Molecular Biology. 25, 9, p. 754-765 12 p.

Rowan University

Research output: Contribution to journalReview article

Peptide Elongation Factors
Peptide Initiation Factors
Mitochondrial Genome
DNA-Directed RNA Polymerases
Motion Pictures
34 Citations (Scopus)

The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice

Manvich, D. F., Webster, K. A., Foster, S. L., Farrell, M. S., Ritchie, J. C., Porter, J. H. & Weinshenker, D., Dec 1 2018, In : Scientific reports. 8, 1, 3840.

Rowan University

Research output: Contribution to journalArticle

Designer Drugs
Clozapine
clozapine N-oxide
Pharmacokinetics
Ligands
2017
3 Citations (Scopus)

A non-canonical multisubunit RNA polymerase encoded by the AR9 phage recognizes the template strand of its uracil-containing promoters

Sokolova, M., Borukhov, S., Lavysh, D., Artamonova, T., Khodorkovskii, M. & Severinov, K., Jan 1 2017, In : Nucleic acids research. 45, 10, p. 5958-5967 10 p.

Rutgers, The State University, Rowan University

Research output: Contribution to journalArticle

Uracil
DNA-Directed RNA Polymerases
Bacteriophages
Bacterial RNA
Bacillus subtilis
6 Citations (Scopus)
Locus Coeruleus
Corticotropin-Releasing Hormone
Synaptic Transmission
Neurons
AMPA Receptors
4 Citations (Scopus)

Different types of pausing modes during transcription initiation

Lerner, E., Ingargiola, A., Lee, J. J., Borukhov, S., Michalet, X. & Weiss, S., Aug 8 2017, In : Transcription. 8, 4, p. 242-253 12 p.

Rowan University

Research output: Contribution to journalReview article

Transcription
Nucleotides
Elongation
Molecules
1 Citation (Scopus)

Endonucleolytic cleavage in the expansion segment 7 of 25S rRNA is an early marker of low-level oxidative stress in yeast

Shedlovskiy, D., Zinskie, J. A., Gardner, E., Pestov, D. & Shcherbik, N., Jan 1 2017, In : Journal of Biological Chemistry. 292, 45, p. 18469-18485 17 p.

Rowan University

Research output: Contribution to journalArticle

Oxidative stress
Yeast
Oxidative Stress
Yeasts
Reactive Oxygen Species
2 Citations (Scopus)

Inhibition of post-transcriptional steps in ribosome biogenesis confers cytoprotection against chemotherapeutic agents in a p53-dependent manner

Sapio, R. T., Nezdyur, A. N., Krevetski, M., Anikin, L., Manna, V. J., Minkovsky, N. & Pestov, D., Dec 1 2017, In : Scientific reports. 7, 1, 9041.

Rowan University

Research output: Contribution to journalArticle

Cytoprotection
Ribosomes
Camptothecin
3T3 Cells
Ribosomal RNA
24 Citations (Scopus)

Insulin signaling misregulation underlies circadian and cognitive deficits in a Drosophila fragile X model

Monyak, R. E., Emerson, D., Schoenfeld, B. P., Zheng, X., Chambers, D. B., Rosenfelt, C., Langer, S., Hinchey, P., Choi, C. H., McDonald, T. V., Bolduc, F. V., Sehgal, A., McBride, S. M. J. & Jongens, T. A., Aug 1 2017, In : Molecular psychiatry. 22, 8, p. 1140-1148 9 p.

Rowan University

Research output: Contribution to journalArticle

Drosophila
Insulin
Fragile X Syndrome
Phenotype
Metformin
17 Citations (Scopus)

Mechanism of Transcription Anti-termination in Human Mitochondria

Hillen, H. S., Parshin, A. V., Agaronyan, K., Morozov, Y. I., Graber, J. J., Chernev, A., Schwinghammer, K., Urlaub, H., Anikin, M., Cramer, P. & Temiakov, D., Nov 16 2017, In : Cell. 171, 5, p. 1082-1093.e13

Rowan University

Research output: Contribution to journalArticle

G-Quadruplexes
Mitochondria
Transcription
Mitochondrial DNA
Elongation
5 Citations (Scopus)

Methylphenidate Enhances Early-Stage Sensory Processing and Rodent Performance of a Visual Signal Detection Task

Navarra, R. L., Clark, B. D., Gargiulo, A. T. & Waterhouse, B. D., May 1 2017, In : Neuropsychopharmacology. 42, 6, p. 1326-1337 12 p.

Rowan University

Research output: Contribution to journalArticle

Methylphenidate
Rodentia
Geniculate Bodies
Evoked Potentials
Catecholamines
5 Citations (Scopus)

Neurochemical differences between target-specific populations of rat dorsal raphe projection neurons

Prouty, E. W., Chandler, D. & Waterhouse, B., Nov 15 2017, In : Brain research. 1675, p. 28-40 13 p.

Rowan University

Research output: Contribution to journalArticle

Health Services Needs and Demand
Serotonin
Neurons
Nitric Oxide
Prefrontal Cortex
25 Citations (Scopus)

Noradrenergic Modulation of Cognition in Health and Disease

Borodovitsyna, O., Flamini, M. & Chandler, D., Jan 1 2017, In : Neural Plasticity. 2017, 6031478.

Rowan University

Research output: Contribution to journalArticle

Cognition
Norepinephrine
Health
Presynaptic Receptors
Locus Coeruleus
9 Citations (Scopus)

One-step hot formamide extraction of RNA from Saccharomyces cerevisiae

Shedlovskiy, D., Shcherbik, N. & Pestov, D. G., Dec 2 2017, In : RNA biology. 14, 12, p. 1722-1726 5 p.

Rowan University

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Edetic Acid
RNA
Phenol
Yeasts
10 Citations (Scopus)

Retinal pathology is associated with increased blood-retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 inhibitor Darapladib

Acharya, N. K., Qi, X., Goldwaser, E. L., Godsey, G. A., Wu, H., Kosciuk, M. C., Freeman, T. A., Macphee, C. H., Wilensky, R. L., Venkataraman, V. & Nagele, R., Jan 1 2017, In : Diabetes and Vascular Disease Research. 14, 3, p. 200-213 14 p.

Rowan University

Research output: Contribution to journalArticle

Retina
Permeability
Swine
Pathology
Hypercholesterolemia
20 Citations (Scopus)

Structural Basis of Mitochondrial Transcription Initiation

Hillen, H. S., Morozov, Y. I., Sarfallah, A., Temiakov, D. & Cramer, P., Nov 16 2017, In : Cell. 171, 5, p. 1072.e10-1081.e10

Rowan University

Research output: Contribution to journalArticle

Transcription
Mitochondria
Mitochondrial Genome
Gene Expression Regulation
DNA-Directed RNA Polymerases
3 Citations (Scopus)

Studying transcription initiation by RNA polymerase with diffusion-based single-molecule fluorescence

Alhadid, Y., Chung, S. Y., Lerner, E., Taatjes, D. J., Borukhov, S. & Weiss, S., Jul 1 2017, In : Protein Science. 26, 7, p. 1278-1290 13 p.

Rowan University

Research output: Contribution to journalReview article

DNA-Directed RNA Polymerases
Transcription
Fluorescence
Bacterial DNA
Complementary RNA
6 Citations (Scopus)

Trafficking of calcium-permeable and calcium-impermeable AMPA receptors in nucleus accumbens medium spiny neurons co-cultured with prefrontal cortex neurons

Werner, C. T., Murray, C. H., Reimers, J. M., Chauhan, N. M., Woo, K. K. Y., Molla, H. M., Loweth, J. & Wolf, M. E., Apr 1 2017, In : Neuropharmacology. 116, p. 224-232 9 p.

Rowan University

Research output: Contribution to journalArticle

AMPA Receptors
Nucleus Accumbens
Prefrontal Cortex
Calcium
Neurons
9 Citations (Scopus)

Tunable green graphene-silk biomaterials: Mechanism of protein-based nanocomposites

Wang, F., Jyothirmayee Aravind, S. S., Wu, H., Forys, J., Venkataraman, V., Ramanujachary, K. & Hu, X., Oct 1 2017, In : Materials Science and Engineering C. 79, p. 728-739 12 p.

Rowan University

Research output: Contribution to journalArticle

silk
Silk
Graphite
Biocompatible Materials
Biomaterials
2016
9 Citations (Scopus)

Age-dependent increase of blood-brain barrier permeability and neuron-binding autoantibodies in S100B knockout mice

Wu, H., Brown, E. V., Acharya, N. K., Appelt, D. M., Marks, A., Nagele, R. & Venkataraman, V., Apr 15 2016, In : Brain research. 1637, p. 154-167 14 p.

Rowan University

Research output: Contribution to journalArticle

Blood-Brain Barrier
Knockout Mice
Autoantibodies
Permeability
Immunoglobulin G
13 Citations (Scopus)

Age-related changes in prefrontal norepinephrine transporter density: The basis for improved cognitive flexibility after low doses of atomoxetine in adolescent rats

Bradshaw, S. E., Agster, K. L., Waterhouse, B. & Mcgaughy, J. A., Jun 15 2016, In : Brain research. 1641, p. 245-257 13 p.

Rowan University

Research output: Contribution to journalReview article

Norepinephrine Plasma Membrane Transport Proteins
Prefrontal Cortex
Methylphenidate
Reversal Learning
Dopamine beta-Hydroxylase
30 Citations (Scopus)

AMPA Receptor Plasticity in Accumbens Core Contributes to Incubation of Methamphetamine Craving

Scheyer, A. F., Loweth, J. A., Christian, D. T., Uejima, J., Rabei, R., Le, T., Dolubizno, H., Stefanik, M. T., Murray, C. H., Sakas, C. & Wolf, M. E., Nov 1 2016, In : Biological Psychiatry. 80, 9, p. 661-670 10 p.

Rowan University

Research output: Contribution to journalArticle

AMPA Receptors
Methamphetamine
Isoxazoles
Cocaine
Nucleus Accumbens

An acute retinal model for evaluating blood retinal barrier breach and potential drugs for treatment

Wu, H., Rodriguez, A. R., Spur, B. W. & Venkataraman, V., Sep 13 2016, In : Journal of Visualized Experiments. 2016, 115, e54619.

Rowan University

Research output: Contribution to journalArticle

Blood-Retinal Barrier
Blood vessels
Histamine
Blood
Immunoglobulin G
29 Citations (Scopus)

Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase

Lernera, E., Chung, S. Y., Allen, B. L., Wang, S., Lee, J., Lu, S. W., Grimaud, L. W., Ingargiola, A., Michalet, X., Alhadid, Y., Borukhov, S., Strick, T. R., Taatjes, D. J. & Weiss, S., Oct 25 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 43, p. E6562-E6571

Rowan University

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Escherichia coli
Nucleosides
RNA Polymerase II
Endonucleases
7 Citations (Scopus)
Bacterial RNA
DNA-Directed RNA Polymerases
Gene expression
Gene Expression
DNA
1 Citation (Scopus)

Data on final calcium concentration in native gel reagents determined accurately through inductively coupled plasma measurements

Viviano, J., Wu, H., Krishnan, A., Ramanujachary, K. & Venkataraman, V., Mar 1 2016, In : Data in Brief. 6, p. 820-822 3 p.

Rowan University

Research output: Contribution to journalArticle

Inductively coupled plasma
Gels
Calcium
Neuronal Calcium-Sensor Proteins
Buffers
3 Citations (Scopus)

Data on the calcium-induced mobility shift of myristoylated and non-myristoylated forms of neurocalcin delta

Viviano, J., Krishnan, A., Wu, H. & Venkataraman, V., Jun 1 2016, In : Data in Brief. 7, p. 630-633 4 p.

Rowan University

Research output: Contribution to journalArticle

Neurocalcin
Calcium
Neuronal Calcium-Sensor Proteins
Proteins
Electrophoresis
1 Citation (Scopus)

Data on the identity and myristoylation state of recombinant, purified hippocalcin

Krishnan, A., Viviano, J., Morozov, Y. & Venkataraman, V., Sep 1 2016, In : Data in Brief. 8, p. 78-81 4 p.

Rowan University

Research output: Contribution to journalArticle

Hippocalcin
Neuronal Calcium-Sensor Proteins
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Information Storage and Retrieval
Amino Acid Sequence
2 Citations (Scopus)

Datasets depicting mobility retardation of NCS proteins observed upon incubation with calcium, but not with magnesium, barium or strontium

Viviano, J., Krishnan, A., Scully, J., Wu, H. & Venkataraman, V., Jun 1 2016, In : Data in Brief. 7, p. 1606-1608 3 p.

Rowan University

Research output: Contribution to journalArticle

Neuronal Calcium-Sensor Proteins
Strontium
Barium
Magnesium
Calcium
9 Citations (Scopus)

Distinct types of translation termination generate substrates for ribosome-associated quality control

Shcherbik, N., Chernova, T. A., Chernoff, Y. O. & Pestov, D. G., Aug 19 2016, In : Nucleic acids research. 44, 14, p. 6840-6852 13 p.

Rowan University

Research output: Contribution to journalArticle

Ribosomes
Quality Control
Peptides
Eukaryotic Large Ribosome Subunits
Ubiquitin-Protein Ligases
6 Citations (Scopus)

Electrophoretic mobility shift in native gels indicates calcium-dependent structural changes of neuronal calcium sensor proteins

Viviano, J., Krishnan, A., Wu, H. & Venkataraman, V., Feb 1 2016, In : Analytical Biochemistry. 494, p. 93-100 8 p.

Rowan University

Research output: Contribution to journalArticle

Neuronal Calcium-Sensor Proteins
Electrophoretic mobility
Gels
Calcium
Ligands
5 Citations (Scopus)

Heterogeneous organization and function of the central noradrenergic system

Waterhouse, B. & Chandler, D., Jun 15 2016, In : Brain research. 1641, p. v-x

Rowan University

Research output: Contribution to journalEditorial

Brain
Brain Stem
Locus Coeruleus
Prosencephalon
Arousal