Center for Advanced Biotechnology and Medicine (CABM)

Research Output 1988 2019

2019
1 Citation (Scopus)
Nucleic Acid Synthesis Inhibitors
Organophosphonates
Viral DNA
DNA-Directed DNA Polymerase
Nucleosides
3 Citations (Scopus)

An ELISA-Based Screening Platform for Ligand–Receptor Discovery

Montelione, G. T. & Comoletti, D., Jan 1 2019, Methods in Enzymology. Wand, A. J. (ed.). Academic Press Inc., p. 453-475 23 p. (Methods in Enzymology; vol. 615).

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

Enzyme-Linked Immunosorbent Assay
Synapses
Proteins
1 Citation (Scopus)

Combining Evolutionary Covariance and NMR Data for Protein Structure Determination

Inouye, M. & Montelione, G. T., Jan 1 2019, Methods in Enzymology. Wand, A. J. (ed.). Academic Press Inc., p. 363-392 30 p. (Methods in Enzymology; vol. 614).

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteins
X Ray Crystallography
Sequence Analysis
Membrane Proteins
3 Citations (Scopus)
Nucleosides
Fingers
Stavudine
DNA
Chemical modification
3 Citations (Scopus)
Open Access
Reverse Transcription
HIV-1
Nucleotides
Thumb
Catalytic Domain
3 Citations (Scopus)
Open Access
Operon
Toxicity
Staphylococcus aureus
Copper
Clone Cells
2018
4 Citations (Scopus)

A hybrid approach for protein structure determination combining sparse NMR with evolutionary coupling sequence data

Montelione, G., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 153-169 17 p. (Advances in Experimental Medicine and Biology; vol. 1105).

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

Nuclear magnetic resonance
Proteins
Sequence Alignment
Excited states
Structural analysis
2 Citations (Scopus)
Homologous Recombination
DNA Repair
DNA Damage
Repair
Double-Stranded DNA Breaks
12 Citations (Scopus)
Immunoprecipitation
Transcription Factors
Monoclonal Antibodies
Immunoblotting
Proteins
1 Citation (Scopus)
Maltose-Binding Proteins
Rhizopus
Chemical shift
Lipase
Fusion reactions
8 Citations (Scopus)
Ribonuclease H
Catalytic Domain
RNA-Directed DNA Polymerase
Nucleic Acid Heteroduplexes
RNA
8 Citations (Scopus)
Oxyclozanide
Niclosamide
Ethanolamine
Colonic Neoplasms
Neoplasm Metastasis
7 Citations (Scopus)
Enzyme kinetics
Alcohol Dehydrogenase
Alcohols
Enzymes
X rays
6 Citations (Scopus)

Inhibitor Bound Dengue NS2B-NS3pro Reveals Multiple Dynamic Binding Modes

Montelione, G. T., Mar 13 2018, In : Biochemistry. 57, 10, p. 1591-1602 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Severe Dengue
Dengue
Polyproteins
Drug Design
Viruses
5 Citations (Scopus)
Peptides
Oxidation-Reduction
Electrons
Prebiotics
Catalysis
5 Citations (Scopus)
Genetic Selection
3' Untranslated Regions
Drosophila melanogaster
Diptera
Haplotypes
Mycobacterium leprae
Rifampin
Mutation
Lepromatous Leprosy
Ribonucleotides
7 Citations (Scopus)
Mycobacterium leprae
Rifampin
Leprosy
Holoenzymes
DNA-Directed RNA Polymerases
8 Citations (Scopus)
3' Untranslated Regions
Introns
Serine
Drosophila
Arginine
2017
8 Citations (Scopus)
Branched Chain Amino Acids
Batch Cell Culture Techniques
Pichia
Yeast
Threonine Dehydratase
11 Citations (Scopus)
Sirolimus
Innate Immunity
Yeast
Drosophila
Yeasts
Hoof and Claw
Tryptophan
Proteins
Nuclear magnetic resonance
Sequence Homology
4 Citations (Scopus)
Organophosphonates
Guanine
DNA-Directed DNA Polymerase
Viruses
Nucleosides
1 Citation (Scopus)
Molecular Dynamics Simulation
Tryptophan
Conformations
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
7 Citations (Scopus)
Escherichia coli Proteins
Alanine
Temperature
Proteins
Heat-Shock Proteins
31 Citations (Scopus)

Principles for designing proteins with cavities formed by curved b sheets

Montelione, G., Jan 13 2017, In : Science. 355, 6321, 6321.

Rutgers, The State University

Research output: Contribution to journalArticle

Ligands
Catalytic Domain
Proteins
Protein Folding
Carrier Proteins
37 Citations (Scopus)
Mycobacterium tuberculosis
Rifampin
DNA-Directed RNA Polymerases
Crystallization
Tuberculosis
5 Citations (Scopus)
HIV Reverse Transcriptase
RNA-Directed DNA Polymerase
Drug Resistance
Mutation
Dideoxynucleosides
5 Citations (Scopus)
Moloney murine leukemia virus
Integrases
Viral DNA
Viruses
Spumavirus
2016
5 Citations (Scopus)

A community resource of experimental data for NMR / X-ray crystal structure pairs

Montelione, G. T., Jan 1 2016, In : Protein Science. 25, 1, p. 30-45 16 p.

Rutgers, The State University

Research output: Contribution to journalReview article

Crystal structure
Nuclear magnetic resonance
X-Rays
X rays
Biomolecular Nuclear Magnetic Resonance
10 Citations (Scopus)
HIV Integrase Inhibitors
Integrase Inhibitors
Integrases
Catalytic Domain
Screening
4 Citations (Scopus)

A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus

Montelione, G. T., Sep 6 2016, In : Structure. 24, 9, p. 1562-1572 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Influenza B virus
Binding Sites
RNA
Influenza A virus
Mutant Proteins
115 Citations (Scopus)

Codon influence on protein expression in E. coli correlates with mRNA levels

Montelione, G. T., Jan 21 2016, In : Nature. 529, 7586, p. 358-363 6 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Codon
Escherichia coli
Messenger RNA
Proteins
Genetic Code
17 Citations (Scopus)
Foscarnet
RNA-Directed DNA Polymerase
Nucleotides
Reverse Transcriptase Inhibitors
Catalytic Domain
5 Citations (Scopus)
Rhizopus
Lipases
Lipase
Disulfides
Enzymes
9 Citations (Scopus)
Organophosphonates
human immunodeficiency virus
nucleosides
Enantiomers
Nucleosides
5 Citations (Scopus)
Rilpivirine
HIV-1
HIV Reverse Transcriptase
Ethiopia
RNA-Directed DNA Polymerase
Circadian Rhythm
Drosophila
Phosphorylation
Light
Drosophila Proteins
3 Citations (Scopus)

Introduction of a polar core into the de novo designed protein Top7

Montelione, G. T., Jul 1 2016, In : Protein Science. p. 1299-1307 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Hydrogen
Hydrogen bonds
Proteins
Conformations
Nuclear magnetic resonance
32 Citations (Scopus)
Ligands
Education
Crystallography
Drug Design
Databases
15 Citations (Scopus)

Rapid experimental SAD phasing and hot-spot identification with halogenated fragments

Arnold, E., Jan 1 2016, In : IUCrJ. 3, p. 51-60 10 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Screening
human immunodeficiency virus
fragments
X-Rays
Proteins
18 Citations (Scopus)
Sulfur
Iron
Structural Models
X-Rays
Iron-Sulfur Proteins
14 Citations (Scopus)
Nucleotide Aptamers
RNA-Directed DNA Polymerase
Nucleotides
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
2015
Crystallography
Screening
X-Rays
Drug Discovery
X rays

Adventures in small molecule fragment screening by x-ray crystallography

Arnold, E., Jan 1 2015, Multifaceted Roles of Crystallography in Modern Drug Discovery. Springer Netherlands, p. 197-208 12 p.

Rutgers, The State University

Research output: Chapter in Book/Report/Conference proceedingChapter

Crystallography
crystallography
Screening
screening
fragments
45 Citations (Scopus)

A general computational approach for repeat protein design

Montelione, G., Jan 30 2015, In : Journal of molecular biology. 427, 2, p. 563-575 13 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Proteins
Nanotechnology
Biocompatible Materials
Hot Temperature
23 Citations (Scopus)
Nuclear magnetic resonance
Alteromonadaceae
Proteins
Plasticity
17 Citations (Scopus)
Organophosphonates
Nucleosides
Oxygen
Nucleic Acids
Phosphates
3 Citations (Scopus)

Analysis of the structural quality of the CASD-NMR 2013 entries

Montelione, G. T., Aug 22 2015, In : Journal of biomolecular NMR. 62, 4, p. 527-540 14 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Chemical shift
Redundancy
Research Personnel
Nuclear magnetic resonance
Atoms