Research Output 1988 2020

2020
Moringa
Mesangial Cells
Diabetic Nephropathies
Transcriptome
Glucose

Is rat a good model for assessment of particulate-based taste-masked formulations?

Ali, J., Chiang, M., Lee, J. B., Voronin, G. O., Bennett, J., Cram, A., Kagan, L., Garnett, M. C., Roberts, C. J. & Gershkovich, P., Jan 2020, In : European Journal of Pharmaceutics and Biopharmaceutics. 146, p. 1-9 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
Saliva
Dosage Forms
efavirenz
Mouth
Pharmaceutical Preparations

Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability

Caritá, A. C., Fonseca-Santos, B., Shultz, J. D., Michniak-Kohn, B., Chorilli, M. & Leonardi, G. R., Feb 2020, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 24, 102117.

Rutgers, The State University

Research output: Contribution to journalReview article

Open Access
Vitamins
Ascorbic Acid
Cosmetics
Antioxidants
Drug products
2019
2 Citations (Scopus)
Organic Anion Transporters
Sumoylation
Cyclic AMP-Dependent Protein Kinases
Ubiquitination
Cell Membrane

A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin

Lee, J. B., Radhi, M., Cipolla, E., Gandhi, R. D., Sarmad, S., Zgair, A., Kim, T. H., Feng, W., Qin, C., Adrower, C., Ortori, C. A., Barrett, D. A., Kagan, L., Fischer, P. M., de Moor, C. H. & Gershkovich, P., Dec 1 2019, In : Scientific reports. 9, 1, 15760.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
Therapeutic Uses
Metabolic Networks and Pathways
Nucleosides
Adenosine
Oral Administration
Enoxaparin
Venous Thromboembolism
Gastrectomy
Anticoagulants
Heparin
Open Access
Meningeal Tuberculosis
Rifampin
Cerebrospinal Fluid
Microbial Sensitivity Tests
Therapeutics

Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis

Malekshah, O. M., Sarkar, S., Nomani, A., Patel, N., Javidian, P., Goedken, M., Polunas, M., Louro, P. & Hatefi, A., Oct 2019, In : Journal of Controlled Release. 311-312, p. 273-287 15 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Enzyme Therapy
Prodrugs
Ovarian Neoplasms
Stem Cells
Neoplasm Metastasis
2 Citations (Scopus)

Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition

Hossan, M. S., Chan, Z. Y., Collins, H. M., Shipton, F. N., Butler, M. S., Rahmatullah, M., Lee, J. B., Gershkovich, P., Kagan, L., Khoo, T. J., Wiart, C. & Bradshaw, T. D., Jul 1 2019, In : Cancer Letters. 453, p. 57-73 17 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Cardiac Glycosides
Phosphatidylinositol 3-Kinases
Signal Transduction
Cardenolides
Apocynaceae

Design and evaluation of a CXCR4 targeting peptide 4DV3 as an HIV entry inhibitor and a ligand for targeted drug delivery

Heon Lee, I., Palombo, M. S., Zhang, X., Szekely, Z. & Sinko, P., May 1 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 138, p. 11-22 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Virus Internalization
HIV
Ligands
Peptides
Pharmaceutical Preparations
2 Citations (Scopus)
Galantamine
Transdermal Patch
Crystallization
Adhesives
Pressure
Diabetic Nephropathies
Transcriptome
Identification (control systems)
Glucose
Epigenomics

Evaluation of treatment options for methicillin-resistant Staphylococcus aureus infections in the obese patient

Narayanan, N., Adams, C. D., Kubiak, D. W., Cheng, S., Stoianovici, R., Kagan, L. & Brunetti, L., Jan 1 2019, In : Infection and Drug Resistance. 12, p. 877-891 15 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
Methicillin-Resistant Staphylococcus aureus
Infection
Pharmacokinetics
Obesity
Anti-Bacterial Agents
4 Citations (Scopus)

Inhalation treatment of cystic fibrosis with lumacaftor and ivacaftor co-delivered by nanostructured lipid carriers

Garbuzenko, O. B., Kbah, N., Kuzmov, A., Pogrebnyak, N., Pozharov, V. & Minko, T., Feb 28 2019, In : Journal of Controlled Release. 296, p. 225-231 7 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Cystic Fibrosis
Inhalation
Lipids
Lung
Pharmaceutical Preparations
Open Access
Organic Anion Transporters
Somatomedins
Cyclic AMP-Dependent Protein Kinases
Phosphorylation
Somatomedin Receptors

Interaction of anticancer drugs with human organic anion transporter HOAT4

Liu, C., Zhang, J. & You, G., Jan 1 2019, In : Journal of Oncology. 2019, 1951786.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
Organic Anion Transporters
Drug Interactions
Epirubicin
Mesylates
Pharmaceutical Preparations

Intradermal and transdermal drug delivery using microneedles – Fabrication, performance evaluation and application to lymphatic delivery

Sabri, A. H., Kim, Y., Marlow, M., Scurr, D. J., Segal, J., Banga, A. K., Kagan, L. & Lee, J. B., Jan 1 2019, (Accepted/In press) In : Advanced Drug Delivery Reviews.

Rutgers, The State University

Research output: Contribution to journalReview article

Pharmaceutical Preparations
Lymphatic System
Hydrogel
Stainless Steel
Silicon

Monitoring the topical delivery of ultrasmall gold nanoparticles using optical coherence tomography

Xu, Q., Jalilian, E., Fakhoury, J. W., Manwar, R., Michniak-Kohn, B., Elkin, K. B. & Avanaki, K., Jan 1 2019, (Accepted/In press) In : Skin Research and Technology.

Rutgers, The State University

Research output: Contribution to journalArticle

Optical Coherence Tomography
Gold
Nanoparticles
Dimethyl Sulfoxide
Topical Administration
1 Citation (Scopus)

Nanocarrier-based systems for targeted and site specific therapeutic delivery

Majumder, J., Taratula, O. & Minko, T., Apr 1 2019, In : Advanced Drug Delivery Reviews. 144, p. 57-77 21 p.

Rutgers, The State University

Research output: Contribution to journalReview article

Pharmaceutical Preparations
Nanoparticles
Therapeutics
Modern 1601-history
Drug Carriers
Valproic Acid
Raman Spectrum Analysis
Fourier Transform Infrared Spectroscopy
Microscopy
Thermogravimetry
1 Citation (Scopus)

Paris Saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-κB pathway

Chen, M., Ye, K., Zhang, B., Xin, Q., Li, P., Kong, A-N., Wen, X. & Yang, J., Jan 1 2019, In : Pharmacological Research. 139, p. 273-285 13 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Carcinogenesis
Dynamins
HCT116 Cells
Colorectal Neoplasms
2 Citations (Scopus)

Prevention of paclitaxel-induced neuropathy by formulation approach

Zang, X., Lee, J. B., Deshpande, K., Garbuzenko, O. B., Minko, T. & Kagan, L., Jun 10 2019, In : Journal of Controlled Release. 303, p. 109-116 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Paclitaxel
Liposomes
Inhibitory Concentration 50
Peripheral Nervous System Diseases
Spinal Cord

Simultaneous quantification of ondansetron and tariquidar in rat and human plasma using a high performance liquid chromatography-ultraviolet method

Chong, Y. E., Chiang, M., Deshpande, K., Haroutounian, S., Kagan, L. & Lee, J. B., Nov 1 2019, In : Biomedical Chromatography. 33, 11, e4653.

Rutgers, The State University

Research output: Contribution to journalArticle

Plasma (human)
Ondansetron
High performance liquid chromatography
Rats
High Pressure Liquid Chromatography
2 Citations (Scopus)

Somatosensory predictors of response to pregabalin in painful chemotherapy-induced peripheral neuropathy: A randomized, placebo-controlled, crossover study

Hincker, A., Frey, K., Rao, L., Wagner-Johnston, N., Abdallah, A. B., Tan, B., Amin, M., Wildes, T., Shah, R., Karlsson, P., Bakos, K., Kosicka, K., Kagan, L. & Haroutounian, S., Aug 2019, In : Pain. 160, 8, p. 1835-1846 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Peripheral Nervous System Diseases
Cross-Over Studies
Placebos
Drug Therapy
oxaliplatin
Open Access
Nanotechnology
Genetic Therapy
Inhalation
Lung Neoplasms
Non-Small Cell Lung Carcinoma

The mechanistic links between insulin and human organic anion transporter 4

Wang, H., Zhang, J. & You, G., Jan 30 2019, In : International Journal of Pharmaceutics. 555, p. 165-174 10 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Organic Anion Transporters
Insulin
Glucocorticoids
Pharmaceutical Preparations
Ligases
Organic Anion Transporters
Sumoylation
Peptide Hydrolases
Kidney
Poisons

Workshop report: USP workshop on exploring the science of drug absorption

Martinez, M. N., Bhoopathy, S., Carlert, S., Cirit, M., Fahmy, R., Flanagan, T., Forbes, B., Jamei, M., Khan, M. A., Lukacova, V., Mochel, J. P., Pepin, X., Pade, D., Reppas, C., Sinko, P. J., Sperry, D., Tsinman, K. & Vertzoni, M., Aug 2019, In : Dissolution Technologies. 26, 3, p. 38-66 29 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
Pharmacopoeias
Education
Pharmaceutical Preparations
United States Food and Drug Administration
Canidae
2018
2 Citations (Scopus)
TYK2 Kinase
Janus Kinase 2
Organic Anion Transporters
Down-Regulation
Ubiquitination
2 Citations (Scopus)

A novel chemotherapeutic protocol for peritoneal metastasis and inhibition of relapse in drug resistant ovarian cancer

Sarkar, S., Malekshah, O. M., Nomani, A., Patel, N. & Hatefi, A., Aug 2018, In : Cancer Medicine. 7, 8, p. 3630-3641 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Ovarian Neoplasms
irinotecan
Neoplasm Metastasis
Recurrence
Neoplastic Stem Cells
5 Citations (Scopus)
Curcumin
Pharmacokinetics
Ions
Plasmas
Calibration
3 Citations (Scopus)

Bioengineering a non-genotoxic vector for genetic modification of mesenchymal stem cells

Chen, X., Nomani, A., Patel, N., Nouri, F. S. & Hatefi, A., Jan 1 2018, In : Biomaterials. 152, p. 1-14 14 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Bioengineering
Genetic Vectors
Stem cells
Mesenchymal Stromal Cells
Stem Cells

Correction to: In Vitro-In Vivo Dose Response of Ursolic Acid, Sulforaphane, PEITC, and Curcumin in Cancer Prevention (The AAPS Journal, (2018), 20, 1, (19), 10.1208/s12248-017-0177-2)

Ramirez, C. N., Li, W., Zhang, C., Wu, R., Su, S., Wang, C., Gao, L., Yin, R. & Kong, A. N. T., Mar 1 2018, In : AAPS Journal. 20, 2, 27.

Rutgers, The State University

Research output: Contribution to journalComment/debate

Curcumin
PubMed
Names
Neoplasms
In Vitro Techniques
9 Citations (Scopus)

Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells

Li, W., Su, Z. Y., Guo, Y., Zhang, C., Wu, R., Gao, L., Zheng, X., Du, Z. Y., Zhang, K. & Kong, A. N., Feb 19 2018, In : Chemical Research in Toxicology. 31, 2, p. 88-96 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Antioxidant Response Elements
Curcumin
Prostatic Neoplasms
Phase II Metabolic Detoxication
Genes
2 Citations (Scopus)

DACT2 Epigenetic Stimulator Exerts Dual Efficacy for Colorectal Cancer Prevention and Treatment

Lu, L., Wang, Y., Ou, R., Feng, Q., Ji, L., Zheng, H., Guo, Y., Qi, X., Kong, A-N. & Liu, Z., Mar 1 2018, In : Pharmacological Research. 129, p. 318-328 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Epigenomics
Colorectal Neoplasms
Catenins
Carcinogenesis
HCT116 Cells
2 Citations (Scopus)
Gels
Irritants
Skin
Adapalene
Nanospheres
13 Citations (Scopus)

DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice

Guo, Y., Wu, R., Gaspar, J. M., Sargsyan, D., Su, Z. Y., Zhang, C., Gao, L., Cheng, D., Li, W., Wang, C., Yin, R., Fang, M., Verzi, M., Hart, R. & Kong, A-N., May 3 2018, In : Carcinogenesis. 39, 5, p. 669-680 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Curcumin
Colitis
Transcriptome
Colonic Neoplasms
Azoxymethane
2 Citations (Scopus)

Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle

Ji, W., Wang, L., He, S., Yan, L., Li, T., Wang, J., Kong, A. N. T., Yu, S. & Zhang, Y., Dec 2018, In : PLoS ONE. 13, 12, e0208474.

Rutgers, The State University

Research output: Contribution to journalArticle

Antioxidant Response Elements
Hypoxia-Inducible Factor 1
Skeletal Muscle
Small Interfering RNA
Myoblasts
8 Citations (Scopus)
Permeability
Skin
Nigella sativa
Polysorbates
Oleic Acid
1 Citation (Scopus)

Emerging Roles for Clinical Pharmacometrics in Cancer Precision Medicine

Nair, S. & Kong, A-N., Jun 1 2018, In : Current Pharmacology Reports. 4, 3, p. 276-283 8 p.

Rutgers, The State University

Research output: Contribution to journalEditorial

Precision Medicine
Oncology
Medicine
Neoplasms
Patient Care
3 Citations (Scopus)

Epigenetic alterations in TRAMP mice: Epigenome DNA methylation profiling using MeDIP-seq

Li, W., Huang, Y., Sargsyan, D., Khor, T. O., Guo, Y., Shu, L., Yang, A. Y., Zhang, C., Paredes-Gonzalez, X., Verzi, M., Hart, R. & Kong, A-N., Jan 12 2018, In : Cell and Bioscience. 8, 1, 3.

Rutgers, The State University

Research output: Contribution to journalArticle

Methylation
DNA Fingerprinting
DNA Methylation
Immunoprecipitation
Epigenomics
3 Citations (Scopus)

Evaluation of Affinisol® HPMC polymers for direct compression process applications

Khatri, P., Katikaneni, P., Desai, D. & Minko, T., Oct 1 2018, In : Journal of Drug Delivery Science and Technology. 47, p. 461-467 7 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Polymers
Powders
Transition Temperature
Hardness
Pressure
3 Citations (Scopus)
Flow cytometry
Stem cells
Mesenchymal Stromal Cells
Flow Cytometry
DNA
Pharmacokinetics
Growth
Rodentia
Monoclonal Antibodies
Laboratory Animals
12 Citations (Scopus)

Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’ project

Hens, B., Sinko, P., Job, N., Dean, M., Al-Gousous, J., Salehi, N., Ziff, R. M., Tsume, Y., Bermejo, M., Paixão, P., Brasseur, J. G., Yu, A., Talattof, A., Benninghoff, G., Langguth, P., Lennernäs, H., Hasler, W. L., Marciani, L., Dickens, J., Shedden, K. & 3 others, Sun, D., Amidon, G. E. & Amidon, G. L., Sep 5 2018, In : International Journal of Pharmaceutics. 548, 1, p. 120-127 8 p.

Rutgers, The State University

Research output: Contribution to journalReview article

Hydrodynamics
Pharmaceutical Preparations
Gastrointestinal Tract
Computing Methodologies
Biopharmaceutics
10 Citations (Scopus)

Fucoxanthin Elicits Epigenetic Modifications, Nrf2 Activation and Blocking Transformation in Mouse Skin JB6 P+ Cells

Yang, Y., Yang, I., Cao, M., Su, Z. Y., Wu, R., Guo, Y., Fang, M. & Kong, A-N., Mar 1 2018, In : AAPS Journal. 20, 2, 32.

Rutgers, The State University

Research output: Contribution to journalArticle

Epigenomics
Skin
Antioxidant Response Elements
Luciferases
Oxidative Stress
4 Citations (Scopus)

Histone Methyltransferase Setd7 Regulates Nrf2 Signaling Pathway by Phenethyl Isothiocyanate and Ursolic Acid in Human Prostate Cancer Cells

Wang, C., Shu, L., Zhang, C., Li, W., Wu, R., Guo, Y., Yang, Y. & Kong, A-N., Sep 1 2018, In : Molecular Nutrition and Food Research. 62, 18, 1700840.

Rutgers, The State University

Research output: Contribution to journalArticle

ursolic acid
isothiocyanates
methyltransferases
prostatic neoplasms
histones
11 Citations (Scopus)
Clotrimazole
Gels
Skin
Fluorescein
Surface-Active Agents
12 Citations (Scopus)

In Vitro-In Vivo Dose Response of Ursolic Acid, Sulforaphane, PEITC, and Curcumin in Cancer Prevention

Ramirez, C. N., Li, W., Zhang, C., Wu, R., Su, S., Wang, C., Gao, L., Yin, R. & Kong, A-N., Jan 1 2018, In : AAPS Journal. 20, 1, 19.

Rutgers, The State University

Research output: Contribution to journalReview article

Curcumin
Phytochemicals
Isothiocyanates
Neoplasms
Animal Models
4 Citations (Scopus)

Isoniazid-loaded orodispersible strips: Methodical design, optimization and in vitro-in silico characterization

Adeleke, O. A., Tsai, P. C., Karry, K. M., Monama, N. O. & Michniak-Kohn, B., Aug 25 2018, In : International Journal of Pharmaceutics. 547, 1-2, p. 347-359 13 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Isoniazid
Computer Simulation
Thermodynamics
Polyvinyl Alcohol
Mouth Mucosa