Lewis-Sigler Institute for Integrative Genomics

Fingerprint Dive into the research topics where Lewis-Sigler Institute for Integrative Genomics is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Drosophila Medicine & Life Sciences
Embryonic Structures Medicine & Life Sciences
Genes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Genome Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Gene expression Chemical Compounds
Mutation Medicine & Life Sciences

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Projects 2008 2021

Research Output 1965 2019

Accurate genome-wide predictions of spatiotemporal gene expression during embryonic development

Zhou, J., Schor, I. E., Yao, V., Theesfeld, C. L., Marco-Ferreres, R., Tadych, A., Furlong, E. E. M. & Troyanskaya, O. G., Jan 1 2019, In : PLoS genetics. 15, 9, e1008382.

Princeton University

Research output: Contribution to journalArticle

Open Access
embryonic development
gene expression
Embryonic Development
embryogenesis
genome
1 Citation (Scopus)

A Computational Framework for Genome-wide Characterization of the Human Disease Landscape

Lee, Y. S., Krishnan, A., Oughtred, R., Rust, J., Chang, C. S., Ryu, J., Kristensen, V. N., Dolinski, K., Theesfeld, C. L. & Troyanskaya, O. G., Feb 27 2019, In : Cell Systems. 8, 2, p. 152-162.e6

Princeton University

Research output: Contribution to journalArticle

Genome
Drug Repositioning
Rare Diseases
Neuroblastoma
Transcriptome

A likelihood-free estimator of population structure bridging admixture models and principal components analysis

Cabreros, I. & Storey, J. D., Aug 1 2019, In : Genetics. 212, 4, p. 1009-1029 21 p.

Princeton University

Research output: Contribution to journalArticle

Open Access
Principal Component Analysis
Population
Genotype
Likelihood Functions
Genetic Structures