Keyphrases
Nonalcoholic Steatohepatitis
92%
Zinc
57%
Zinc Metallochaperones
56%
Flow Cytometry
56%
Mutant p53
52%
Liver
44%
Oxidative Stress
43%
Nitrogen mustard
36%
Diet-induced
32%
Knock-in Mouse Model
32%
Methionine
30%
Lung Injury
29%
Farnesoid X Receptor
29%
Choline-deficient
28%
Chromium
28%
Rodents
28%
Metallothionein
27%
Sprague-Dawley Rats
26%
CSF1R
26%
Placenta
24%
Apoptosis
24%
IC50
23%
Fibrosis
21%
Cadmium
21%
In Cancer
21%
Bile Acid Homeostasis
21%
Bile Acids
20%
MRNA Expression
20%
Acute Toxicity
20%
Non-alcoholic Fatty Liver Disease (NAFLD)
20%
Inflammation
20%
Mutant p53 Reactivation
20%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
20%
Differential Effects
20%
Hepatotoxicity
19%
Induced Toxicity
19%
Flow Cytometric
19%
Fgf15
19%
High Affinity
19%
High-fat Diet
19%
Multidrug Resistance Protein
19%
Cell Proliferation
19%
Phagocytosis
19%
Fetal Tissue
18%
Colony-stimulating Factor 1 Receptor Inhibitor
18%
Apoptosis Induction
18%
Psoralen
18%
Possible Mechanisms
18%
Endoplasmic Reticulum Stress (ER stress)
18%
Recombinant Human
18%
Interleukin-3
18%
Normal Volunteers
18%
Arylamides
18%
Microcystin-LR (MC-LR)
18%
Human Peripheral Blood Lymphocytes
18%
Methotrexate
18%
Ice Morphology
18%
Engineered Nanomaterials
18%
Ice-binding Protein
18%
Novel Inhibitors
18%
MeHg
18%
Methylmercury
18%
Gestational Day
18%
Growth Inhibition
18%
Epigallocatechin-3-gallate
17%
Cr(VI)
17%
Pharmacodynamics
17%
Pharmacokinetics
17%
Mouse Model
15%
Phorbol 12-myristate 13-acetate
15%
Double Knockout Mice
15%
Hepatocytes
15%
Tumor
15%
Protein Expression
15%
Highly Effective
14%
Female Mice
14%
Nanoplastics
14%
Transporter Expression
14%
Lung
14%
Multidrug Resistance Protein 1 (MDR1)
14%
CYP27A1
14%
CYP7A1
14%
Hexavalent Chromium
14%
Small Molecules
13%
Cell Wall
13%
Rheumatoid Arthritis
13%
Obesity
13%
Dose Effect
13%
Wild Mice
13%
Breast Cancer
13%
Macrophages
13%
Morphological Changes
13%
Monocytes
13%
Aorta
12%
Diabetic
12%
Cytotoxicity
12%
Thiosemicarbazone
12%
Cadmium Chloride
12%
Reactive Oxygen Species
12%
Nuclear Receptor
12%
Acetaminophen Hepatotoxicity
12%
H2 Production
12%
Bcrp
12%
Phosphorylation
12%
Self-renewal
12%
Mitochondrial Uncoupling
12%
Phenyl
12%
Granulocyte Colony-stimulating Factor (G-CSF)
12%
Tumor Growth
12%
Novel Class
12%
Hydrogen Peroxide
12%
Pancreatic Cancer
11%
Zn2+
11%
Acetaminophen APAP
11%
Uterine Artery
11%
Carbon Tetrachloride
11%
Liver Fibrosis
11%
Copper Binding
11%
Cytochrome
11%
Kinase Inhibitor
11%
Growth Factors
11%
Potential Therapeutics
11%
Mechanism of Action
11%
Lung Macrophages
11%
Tea Polyphenols
11%
Insulin
11%
In Vivo Activity
11%
Translocated
11%
Cancer Cell Lines
11%
Inflammatory Response
11%
Ca2+
11%
Potassium Dichromate
11%
Effluent
11%
Rat Hepatoma Cells
10%
Green Tea Polyphenols
10%
Cholesterol
10%
Solid Tumors
10%
Blood Vessels
10%
Gut Microbiome
10%
Increased Vulnerability
10%
Propidium Iodide
10%
Inhalation
10%
Disease Model
10%
Chagas Cardiomyopathy
10%
Small Heterodimer Partner
10%
Metabolic Syndrome
10%
Kidney
10%
Peroxide
10%
Chemotherapy
10%
T Cell Activation
10%
Cancer Stem-like
10%
Epidermal Cells
10%
Microplastics
10%
Macrophage Activation
10%
Epigallocatechin
10%
Platelet Count
10%
Liver Toxicity
10%
Granulocytes
10%
Surfactant Protein D (SP-D)
10%
Microparticles
10%
Neuronal Differentiation
10%
C-Jun N-terminal Kinase Signaling
10%
Mitogen-activated Protein Kinase
9%
Protective Behavior
9%
Cellular Assay
9%
Aerosol
9%
Toxicokinetics
9%
Multidrug Resistance-associated Protein 2 (MRP2)
9%
Magnetic Resonance Imaging
9%
Ethyl
9%
Null Mice
9%
Adverse Effects
9%
Zinc Binding
9%
P53 mutant
9%
Bone Morphogenetic Protein Receptor
9%
Receptor Antagonist
9%
Combinational Therapy
9%
Circulating Platelets
9%
Polystyrene Nanospheres
9%
Skin Inflammation
9%
Saccharomyces Cerevisiae
9%
Defense Mechanisms
9%
Microglia
9%
Isothiocyanates
9%
Flavin-dependent Monooxygenase
9%
Joint Swelling
9%
Acetaminophen-induced Hepatotoxicity
9%
Environmental Exposure Assessment
9%
2-Aminopurine
9%
Genomic Deletion
9%
Chronic Chagas Disease
9%
Cell Growth Inhibition
9%
Transcriptional Regulation
9%
Enzyme Treatment
9%
Redox-sensitive
9%
Human Lung Cancer
9%
Xenobiotic Transporters
9%
T-cell Acute Lymphoblastic Leukemia (T-ALL)
9%
Immunological Tests
9%
Synthetic Peptides
9%
Placenta Tissue
9%
Anti-tumor Necrosis Factor (anti-TNF)
9%
Ricin Inhibitors
9%
Clinical Evidence
9%
2-quinolone
9%
Body Composition
9%
MST1
9%
CD8+ T Cells
9%
Immunoglobulin Concentration
9%
Human Bronchial Cells
9%
Safety Monitoring
9%
Lung Exposure
9%
TP53 mutant
9%
Nanopolystyrene
9%
Sodium Dodecyl Sulfate
9%
Phosphatidylserine Externalization
9%
Raspberry Ketone
9%
Switch Mechanism
9%
Acetaminophen Toxicity
9%
Black Tea Polyphenol
9%
Cyano
9%
Sex Differences
9%
Acetaminophen
9%
Metformin
9%
Hydroxylase
9%
Hydrazone
9%
Moringa Leaf Extract
9%
Mouse Ear Edema
9%
Potentiation
9%
2-Butanone
9%
Digestion
9%
P-hydroxyphenyl
9%
Serum Immunoglobulins
9%
Nonclinical Safety
9%
Tumor Cell Survival
9%
Oyster
9%
Hepatoma Cells
9%
Peritoneal Metastasis
9%
Breast Cancer Susceptibility Gene 1 (BRCA1)
9%
Cancer Stem Cells
9%
Vitamin D Compounds
9%
Platelets
9%
Bone Effects
9%
Thrombopoietin Receptor Agonists (TPO-RAs)
9%
Tyrosine Phosphorylation
9%
Hepatocellular Carcinoma
9%
Platelet Levels
9%
Neuronal Cells
9%
Environmental Assessment
9%
Apoptotic Cells
9%
Isobologram Analysis
9%
Tissue Destruction
9%
Cardiomyopathy
9%
Hypertensive
9%
Acetyl
9%
Mouse Splenocytes
9%
Cord Blood Monocytes
9%
BMI1
9%
Serum Immunoglobulin G
9%
Live Animal Imaging
9%
Hepatic Metastasis
9%
System Level
9%
Cell Survival Signaling
9%
Intoxication
9%
Superoxide Production
9%
Stress-induced
9%
In Vivo Effects
9%
Block Freeze Concentration
9%
Carboxamide
9%
Dimethylamino
9%
Sensitive Mechanism
9%
Health Implications
9%
Bioengineering
9%
Immune Response
9%
Benzisothiazolinone
9%
Mustard Vesicants
9%
Adipose-derived Stem Cells
9%
Ovarian Cancer
9%
Megakaryocytes
9%
Feeding Suppression
9%
Feeding Toxicity
9%
Acute Feeding
9%
Polyamines
9%
Pregnant Rats
9%
Transplantation Model
9%
Coronary Dysfunction
9%
Cell Growth & Apoptosis
9%
Therapeutic Targeting
9%
ATP-binding Cassette Transporter A1 (ABCA1)
9%
Theaflavin Digallate
9%
SN-38
9%
Gene-environment Interaction
9%
Sterol 27-hydroxylase
9%
C-Jun
9%
Carbonate
9%
Epitope
9%
Autism
9%
Sex Chromosomes
9%
Male Fetus
9%
Genistein
9%
Pharmacology, Toxicology and Pharmaceutical Science
Nonalcoholic Fatty Liver
100%
Protein P53
56%
Metallochaperone
55%
Knockout Mouse
55%
Hepatotoxicity
46%
Paracetamol
46%
Malignant Neoplasm
44%
Sprague Dawley Rat
44%
Diseases
41%
Nitrogen Mustard
36%
Colony Stimulating Factor 1
36%
Pharmacodynamics
35%
Mouse Model
33%
Receptor
33%
Methionine
32%
Choline
31%
Bile Acid
31%
Farnesoid X Receptor
30%
Messenger RNA
30%
Phosphotransferase
28%
Breast Cancer
27%
Liver Cell Carcinoma
27%
Metallothionein
27%
Nanoplastics
27%
Neoplasm
26%
Pharmacokinetics
25%
Inflammation
25%
Fibrosis
24%
IC50
23%
Flow Cytometry
23%
Acute Toxicity
20%
Transcription Factor Nrf2
19%
Nutritional Deficiency
19%
Fibroblast Growth Factor
19%
Wild Type Mouse
18%
Normal Human
18%
Interleukin 3
18%
Polyphenol
18%
Microcystin-LR
18%
Methotrexate
18%
Nanomaterial
18%
Exposure
18%
Nanoparticle
16%
Reactive Oxygen Metabolite
15%
12-O-Tetradecanoylphorbol-13-Acetate
15%
Anti-Inflammatory Drug
15%
Hydrogen Peroxide
15%
Styrofoam
15%
Chemotherapy
14%
Protein Kinase C
13%
ABCG2
13%
Structure Activity Relationship
13%
Epigallocatechin Gallate
12%
Cytochrome
12%
Theaflavin
12%
Toxicology
12%
Phosphotransferase Inhibitor
11%
Liver Fibrosis
11%
Exposure Assessment
11%
Carboxamide
11%
Zinc Ion
11%
Cell Nucleus Receptor
11%
Effusion
11%
Immunoglobulin
11%
Polyamide
11%
Acetic Acid Derivative
10%
Metabolic Syndrome X
10%
Disease Model
10%
Ionophore
10%
Growth Factor
10%
CYP27A1
10%
Cholesterol 7alpha Monooxygenase
10%
Multidrug Resistance Associated Protein 4
10%
Surfactant Protein D
10%
Tumor Necrosis Factor
10%
Heterodimer
9%
Toxic Injury
9%
Table Salt
9%
Toxicokinetics
9%
Solid Malignant Neoplasm
9%
Dermatitis
9%
Chagas Disease
9%
Broxuridine
9%
Isothiocyanate
9%
2 Aminopurine
9%
Recombinant Granulocyte Colony Stimulating Factor
9%
Ovary Cancer
9%
Nuclear Magnetic Resonance Imaging Agent
9%
Synergism
9%
Quinolone Derivative
9%
Dimethylaniline Monooxygenase
9%
Ricin
9%
T Cell Leukemia
9%
Raccoon
9%
Cytochrome P450
9%
Thrombopoietin
9%
Moringa
9%
Raspberry
9%
2 Butanone
9%
Acute Lymphoblastic Leukemia
9%
Thiosemicarbazone Derivative
9%
Environmental Exposure
9%
Metformin
9%
Imidazole
9%
Ear Edema
9%
microRNA
9%
Moringa oleifera
9%
Vitamin D
9%
High-Fat Diet-Induced Steatohepatitis
9%
Enzyme Prodrug Therapy
9%
Murine
9%
Immunogenicity
9%
Mitogen Activated Protein Kinase
9%
Synthetic Peptide
9%
Safety Assessment
9%
Uterus Horn
9%
Fibroblast Growth Factor 19
9%
Chagas Cardiomyopathy
9%
Pravastatin
9%
Magnetite Nanoparticle
9%
Protein Kinase Fer
9%
microRNA 145
9%
Adefovir
9%
Sodium Orthovanadate
9%
Homocysteine
9%
Elongation Factor 2 Kinase
9%
Sterol Regulatory Element Binding Protein
9%
Multidrug Resistance Associated Protein 3
9%
Diclofenac
9%
Tyrosinase
9%
Proteinase K
9%
Sodium Dodecyl Sulfate
9%
Paraquat
9%
Multidrug Resistance Protein 1
9%
Nonoxynol-9
9%
Gold Nanoparticle
9%
Inductively Coupled Plasma
9%
Protein Tyrosine Kinase
9%
Acute Myeloid Leukemia
9%
Sulfonylurea
9%
Bone Metastasis
9%
Chemokine Receptor CXCR2
9%
Protein Tyrosine Kinase Inhibitor
9%
Carboxylate
9%
Immunoglobulin G
9%
Pneumonia
9%
Glucose Transporter
9%
Proline
9%
Cognitive Defect
9%
Acyl Coenzyme A Desaturase 1
9%
Myocardial Disease
9%
Gonadorelin
9%
Cardiovascular Disease
9%
Genistein
9%
Phytoestrogen
9%
Dyslipidemia
9%
Nanosphere
9%
Cell Culture
9%
Perfluorooctanoic Acid
9%
Taurocholic Acid
9%
Carbon Tetrachloride-Induced Liver Injury
9%
Kidney Stone
9%
Cystine
9%
Cystinuria
9%
Ephrin
9%
Methylmercury
9%
Embryonal Carcinoma
9%
Carbon Tetrachloride
8%
Infection
8%
Acetoacetic Acid
8%
Alanine Aminotransferase
8%
Biological Marker
7%
Epigallocatechin
7%
Arthritis
7%
Hexavalent Chromium
7%
Rheumatoid Arthritis
7%
Inflammatory Arthritis
7%
Maternal Exposure
7%
Liver Injury
7%
Western Blot
7%
Spermicidal Agent
7%
Triacylglycerol
7%
Subcutaneous Injection
6%
Leukemia
6%
Hypercholesterolemia
6%
Phosphoprotein
6%
Indazole Derivative
6%
Betulin
6%
Free Radical
6%
Thiosemicarbazone
5%
Tumor Growth
5%
Quercetin
5%
Acute Lung Injury
5%
Polypeptide
5%
Tumor Necrosis Factor Antibody
5%
Perfluorooctanesulfonic Acid
5%
Perfluorohexanesulfonic Acid
5%
Glutathione
5%
Metal Ion
5%
Cytotoxicity
5%
Adverse Drug Reaction
5%