School of Arts and Sciences, Molecular Biology & Biochemistry

Rutgers, The State University

78272 Citations
137 h-index
663 Article
86 Review article
22 Comment/debate
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2025
Autophagy-related 7 (ATG7) regulates food intake and liver health during asparaginase exposure
Zalma, B. A., Ibrahim, M., Rodriguez-Polanco, F. C., Bhavsar, C. T., Rodriguez, E. M., Cararo-Lopes, E., Farooq, S. A., Levy, J. L., Wek, R. C., White, E. & Anthony, T. G., Feb 2025, In: Journal of Biological Chemistry. 301, 2, 108171.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Diet-induced obesity mediated through estrogen-related receptor α is independent of intestinal function
Vemuri, K., Iqbal, J., Kumar, S., Logerfo, A., Ibrahim, M., White, E. & Verzi, M. P., Feb 2025, In: Journal of Biological Chemistry. 301, 2, 108197.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
2024
A conserved requirement for RME-8/DNAJC13 in neuronal autophagic lysosome reformation
Swords, S. B., Jia, N., Norris, A., Modi, J., Cai, Q. & Grant, B. D., 2024, In: Autophagy. 20, 4, p. 792-808 17 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes
Banse, S. A., Sedore, C. A., Johnson, E., Coleman-Hulbert, A. L., Onken, B., Hall, D., Jackson, E. G., Huynh, P., Foulger, A. C., Guo, S., Garrett, T., Xue, J., Inman, D., Morshead, M. L., Plummer, W. T., Chen, E., Bhaumik, D., Chen, M. K., Harinath, G. & Chamoli, M. & 9 others, Quinn, R. P., Falkowski, R., Edgar, D., Schmidt, M. O., Lucanic, M., Guo, M., Driscoll, M., Lithgow, G. J. & Phillips, P. C., Apr 2024, In: GeroScience. 46, 2, p. 2239-2251 13 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer
Lan, T., Arastu, S., Lam, J., Kim, H., Wang, W., Wang, S., Bhatt, V., Lopes, E. C., Hu, Z., Sun, M., Luo, X., Ghergurovich, J. M., Su, X., Rabinowitz, J. D., White, E. & Guo, J. Y., Dec 2024, In: Nature communications. 15, 1, 5857.
Rutgers, The State University, Princeton University
Research output: Contribution to journal › Article › peer-review

Open Access
Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice
Yang, X., Wang, J., Chang, C. Y., Zhou, F., Liu, J., Xu, H., Ibrahim, M., Gomez, M., Guo, G. L., Liu, H., Zong, W. X., Wondisford, F. E., Su, X., White, E., Feng, Z. & Hu, W., Dec 2024, In: Nature communications. 15, 1, 627.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
LRK-1/LRRK2 and AP-3 regulate trafficking of synaptic vesicle precursors through active zone protein SYD-2/Liprin-α
Nadiminti, S. S. P., Dixit, S. B., Ratnakaran, N., Deb, A., Hegde, S., Boyanapalli, S. P. P., Swords, S., Grant, B. D. & Koushika, S. P., May 9 2024, In: PLoS genetics. 20, 5 May, e1011253.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Myosin phosphatase targeting subunit1 controls localization and motility of Rab7-containing vesicles: Is myosin phosphatase a cytoplasmic dynein regulator?
Matsumura, F., Murayama, T., Kuriyama, R., Matsumura, A. & Yamashiro, S., Dec 2024, In: Cytoskeleton. 81, 12, p. 872-882 11 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer
Langer, H. T., Ramsamooj, S., Dantas, E., Murthy, A., Ahmed, M., Ahmed, T., Hwang, S. K., Grover, R., Pozovskiy, R., Liang, R. J., Queiroz, A. L., Brown, J. C., White, E. P., Janowitz, T. & Goncalves, M. D., Aug 2024, In: Acta Physiologica. 240, 8, e14167.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication
Her, J., Zheng, H. & Bunting, S. F., May 15 2024, In: Journal of Clinical Investigation. 134, 10, e167419.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Role of Tumor Cell Intrinsic and Host Autophagy in Cancer
Guo, J. Y. & White, E., Jul 2024, In: Cold Spring Harbor Perspectives in Medicine. 14, 7, a041539.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review
The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background
Banse, S. A., Jackson, E. G., Sedore, C. A., Onken, B., Hall, D., Coleman-Hulbert, A., Huynh, P., Garrett, T., Johnson, E., Harinath, G., Inman, D., Guo, S., Morshead, M., Xue, J., Falkowski, R., Chen, E., Herrera, C., Kirsch, A. J., Perez, V. I. & Guo, M. & 3 others, Lithgow, G. J., Driscoll, M. & Phillips, P. C., 2024, In: Aging. 16, 7, p. 5829-5855 27 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Transposon Removal Reveals Their Adaptive Fitness Contribution
Cranz-Mileva, S., Reilly, E., Chalhoub, N., Patel, R., Atanassova, T., Cao, W., Ellison, C. & Zaratiegui, M., Feb 1 2024, In: Genome biology and evolution. 16, 2, evae010.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
2023

Apoptosis, autophagy, and cancer: the critical role Genes & Development played in paradigm shifts
White, E., Jan 1 2023, In: Genes and Development. 37, 1-2, p. 59-62 4 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
A SARS-CoV-2 Vaccine Designed for Manufacturability Results in Unexpected Potency and Non-Waning Humoral Response
Campbell, E., Dobkin, J., Osorio, L. J., Kolloli, A., Ramasamy, S., Kumar, R., Sant’Angelo, D. B., Subbian, S., Denzin, L. K. & Anderson, S., Apr 2023, In: Vaccines. 11, 4, 832.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Autophagy in PDGFRA⁺ mesenchymal cells is required for intestinal homeostasis and mammalian survival
Yang, Y. & White, E., 2023, In: Autophagy. 19, 2, p. 726-728 3 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Conserved NIMA kinases regulate multiple steps of endocytic trafficking
Joseph, B. B., Naslavsky, N., Binti, S., Conquest, S., Robison, L., Bai, G., Homer, R. O., Grant, B. D., Caplan, S., David & Fay, S., Apr 2023, In: PLoS genetics. 19, 4, e1010741.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease
Liu, P., Anandhan, A., Chen, J., Shakya, A., Dodson, M., Ooi, A., Chapman, E., White, E., Garcia, J. G. & Zhang, D. D., Feb 2023, In: Redox Biology. 59, 102570.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Discovery and Targeting of a Noncanonical Mechanism of Sarcoma Resistance to ADI-PEG20 Mediated by the Microenvironment
Rogers, L. C., Kremer, J. C., Brashears, C. B., Lin, Z., Hu, Z., Bastos, A. C. S., Baker, A., Fettig, N., Zhou, D., Shoghi, K. I., Dehner, C. A., Chrisinger, J. S. A., Bomalaski, J. S., Garcia, B. A., Oyama, T., White, E. P. & Van Tine, B. A., Aug 15 2023, In: Clinical Cancer Research. 29, 16, p. 3189-3202 14 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors
Bhatt, V., Lan, T., Wang, W., Kong, J., Lopes, E. C., Wang, J., Khayati, K., Raju, A., Rangel, M., Lopez, E., Hu, Z. S., Luo, X., Su, X., Malhotra, J., Hu, W., White, E. & Guo, J. Y., Jan 2023, In: Cell Death and Disease. 14, 1, 61.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers
Arnold, M. L., Cooper, J., Androwski, R., Ardeshna, S., Melentijevic, I., Smart, J., Guasp, R. J., Nguyen, K. C. Q., Bai, G., Hall, D. H., Grant, B. D. & Driscoll, M., Dec 2023, In: Nature communications. 14, 1, 4450.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia
Ferrer, M., Mourikis, N., Davidson, E. E., Kleeman, S. O., Zaccaria, M., Habel, J., Rubino, R., Gao, Q., Flint, T. R., Young, L., Connell, C. M., Lukey, M. J., Goncalves, M. D., White, E. P., Venkitaraman, A. R. & Janowitz, T., Jul 11 2023, In: Cell Metabolism. 35, 7, p. 1147-1162.e7
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell
Wang, Y., Arnold, M. L., Smart, A. J., Wang, G., Androwski, R. J., Morera, A., Nguyen, K. C. Q., Schweinsberg, P. J., Bai, G., Cooper, J., Hall, D. H., Driscoll, M. & Grant, B. D., Mar 2 2023, In: eLife. 12
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Macrocephaly and developmental delay caused by missense variants in RAB5C
Koop, K., Yuan, W., Tessadori, F., Rodriguez-Polanco, W. R., Grubbs, J., Zhang, B., Osmond, M., Graham, G., Sawyer, S., Conboy, E., Vetrini, F., Treat, K., Płoski, R., Pienkowski, V. M., Kłosowska, A., Fieg, E., Krier, J., Mallebranche, C., Alban, Z. & Aldinger, K. A. & 27 others, Ritter, D., MacNamara, E., Sullivan, B., Herriges, J., Alaimo, J. T., Helbig, C., Ellis, C. A., Van Eyk, C., Gecz, J., Farrugia, D., Osei-Owusu, I., Adès, L., Van Den Boogaard, M. J., Fuchs, S., Duran, K., Dawson, Z. D., Lindsey, A., Huang, H., Baldridge, D., Silverman, G. A., Grant, B. D., Raizen, D., Van Haaften, G., Pak, S. C., Rehmann, H., Schedl, T. & Van Hasselt, P., Nov 1 2023, In: Human molecular genetics. 32, 21, p. 3063-3077 15 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
Bashkirova, E. V., Klimpert, N., Monahan, K., Campbell, C. E., Osinski, J., Tan, L., Schieren, I., Pourmorady, A., Stecky, B., Barnea, G., Xie, X. S., Abdus-Saboor, I., Shykind, B. M., Marlin, B. J., Gronostajski, R. M., Fleischmann, A. & Lomvardas, S., Dec 18 2023, In: eLife. 12
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
SPE-51, a sperm-secreted protein with an immunoglobulin-like domain, is required for fertilization in C. elegans
Mei, X., Maniates, K. A., Looper, A., Krauchunas, A. R., Druzhinina, M., Dharia, S., Ni, J., Singaravelu, G., Gu, S. G., Shakes, D. C., Grant, B. D. & Singson, A. W., Jul 24 2023, In: Current Biology. 33, 14, p. 3048-3055.e6
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Syndapin and GTPase RAP-1 control endocytic recycling via RHO-1 and non-muscle myosin II
Rodriguez-Polanco, W. R., Norris, A., Velasco, A. B., Gleason, A. M. & Grant, B. D., Nov 20 2023, In: Current Biology. 33, 22, p. 4844-4856.e5
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
2022
Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival
Yang, Y., Gomez, M., Marsh, T., Poillet-Perez, L., Sawant, A., Chen, L., Park, N. R., RaElle Jackson, S., Hu, Z., Alon, N., Liu, C., Debnath, J., Guan, J. L., Davidson, S., Verzi, M. & White, E., May 24 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 21, e2202016119.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Deficiency in RCAT-1 Function Causes Dopamine Metabolism Related Behavioral Disorders in Caenorhabditis elegans
Jeong, H., Park, J. Y., Lee, J. H., Baik, J. H., Kim, C. Y., Cho, J. Y., Driscoll, M. & Paik, Y. K., Feb 1 2022, In: International journal of molecular sciences. 23, 4, 2393.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Identification of an integrase-independent pathway of retrotransposition
Li, F., Lee, M., Esnault, C., Wendover, K., Guo, Y., Atkins, P., Zaratiegui, M. & Levin, H. L., Jul 2022, In: Science advances. 8, 26, eabm9390.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes
Onken, B., Sedore, C. A., Coleman-Hulbert, A. L., Hall, D., Johnson, E., Jones, E. G., Banse, S. A., Huynh, P., Guo, S., Xue, J., Chen, E., Harinath, G., Foulger, A., Chao, E. A., Hope, J., Bhaumik, D., Plummer, T., Inman, D., Morshead, M. & Guo, M. & 3 others, Lithgow, G., Phillips, P. C. & Driscoll, M., Jan 2022, In: Aging cell. 21, 1, e13488.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points
Norris, A., McManus, C. T., Wang, S., Ying, R. & Grant, B. D., Oct 24 2022, In: PLoS genetics. 18, 10, e1010296.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
NDF is a transcription factor that stimulates elongation by RNA polymerase II
Fei, J., Xu, J., Li, Z., Xu, K., Wang, D., Kassavetis, G. A. & Kadonaga, J. T., Mar 1 2022, In: Genes and Development. 34, 5-6, p. 294-299 6 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Reprogramming the piRNA pathway for multiplexed and transgenerational gene silencing in C. elegans
Priyadarshini, M., Ni, J. Z., Vargas-Velazquez, A. M., Gu, S. G. & Frøkjær-Jensen, C., Feb 2022, In: Nature Methods. 19, 2, p. 187-194 8 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
OSBREAC, Dec 2022, In: Communications biology. 5, 1, 834.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Target-dependent suppression of siRNA production modulates the levels of endogenous siRNAs in the Caenorhabditis elegans germline
Gajic, Z., Kaur, D., Ni, J., Zhu, Z., Zhebrun, A., Gajic, M., Kim, M., Hong, J., Priyadarshini, M., Frøkjær-Jensen, C. & Gu, S., Aug 2022, In: Development (Cambridge). 149, 16, dev200692.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer
Khayati, K., Bhatt, V., Lan, T., Alogaili, F., Wang, W., Lopez, E., Hu, Z. S., Gokhale, S., Narita, M., Xie, P., White, E. & Guo, J. Y., Dec 1 2022, In: Cancer Research. 82, 23, p. 4429-4443 15 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration
Huo, Y., Sawant, A., Tan, Y., Mahdi, A. H., Li, T., Ma, H., Bhatt, V., Yan, R., Coleman, J., Dreyfus, C. F., Guo, J. Y., Maral Mouradian, M., White, E. & Xia, B., Apr 11 2022, In: PLoS genetics. 18, 4, e1010138.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Using postal change-of-address data to predict second waves in infections near pandemic epicentres
Schulman, A. & Bhanot, G., Mar 24 2022, In: Epidemiology and Infection. 150, e120.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
2021
Atr/atm-mediated phosphorylation of brca1 t1394 promotes homologous recombinational repair and g2-m checkpoint maintenance
Foo, T. K., Vincelli, G., Huselid, E., Her, J., Zheng, H., Simhadri, S., Wang, M., Huo, Y., Li, T., Yu, X., Li, H., Zhao, W., Bunting, S. F. & Xia, B., Sep 15 2021, In: Cancer Research. 81, 18, p. 4676-4684 9 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Gene expression in barrett’s esophagus cell lines resemble esophageal squamous cell carcinoma instead of esophageal adenocarcinoma
Panda, A., Bhanot, G., Ganesan, S. & Bajpai, M., Dec 1 2021, In: Cancers. 13, 23, 5971.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Investigation of fascin1, a marker of mature dendritic cells, reveals a new role for IL-6 signaling in CCR7-mediated chemotaxis
Matsumura, F., Polz, R., Singh, S., Matsumura, A., Scheller, J. & Yamashiro, S., Aug 1 2021, In: Journal of Immunology. 207, 3, p. 938-949 12 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
MDVs to the rescue: How autophagy-deficient cancer cells adapt to defective mitophagy
Poillet-Perez, L. & White, E., Jul 26 2021, In: Developmental cell. 56, 14, p. 2010-2012 3 p.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes
Liu, Y., Gokhale, S., Jung, J., Zhu, S., Luo, C., Saha, D., Guo, J. Y., Zhang, H., Kyin, S., Zong, W. X., White, E. & Xie, P., Oct 20 2021, In: Frontiers in immunology. 12, 670338.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism
Liu, P., Dodson, M., Li, H., Schmidlin, C. J., Shakya, A., Wei, Y., Garcia, J. G. N., Chapman, E., Kiela, P. R., Zhang, Q. Y., White, E., Ding, X., Ooi, A. & Zhang, D. D., Sep 2021, In: Molecular Metabolism. 51, 101243.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
Wang, X., Zhang, H., Sapio, R., Yang, J., Wong, J., Zhang, X., Guo, J. Y., Van Remmen, H., Li, H., White, E., Liu, C., Kiledjian, M., Pestov, D. G., Steven Zheng, X. F. & Pine, S., Dec 1 2021, In: Nature communications. 12, 1, 2259.
Rutgers, The State University, Rowan University
Research output: Contribution to journal › Article › peer-review

Open Access
Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans
Laranjeiro, R., Harinath, G., Pollard, A. K., Gaffney, C. J., Deane, C. S., Vanapalli, S. A., Etheridge, T., Szewczyk, N. J. & Driscoll, M., Feb 19 2021, In: iScience. 24, 2, 102105.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling
Cooper, J. F., Guasp, R. J., Arnold, M. L., Grant, B. D. & Driscoll, M., Sep 7 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 36, e2101410118.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning
Tang, L. T. H., Trivedi, M., Freund, J., Salazar, C. J., Rahman, M., Ramirez-Suarez, N. J., Lee, G., Wang, Y., Grant, B. D. & Bulow, H. E., Jul 1 2021, In: PLoS genetics. 17, 7, e1009475.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access
The transmission of SARS-CoV-2 is likely comodulated by temperature and by relative humidity
Raines, K. S., Doniach, S. & Bhanot, G., Jul 2021, In: PLoS One. 16, 7 July, e0255212.
Rutgers, The State University
Research output: Contribution to journal › Article › peer-review

Open Access