Alison Krufka

    1991 …2022

    Research activity per year

    Personal profile

    Research interests

    Research Expertise: 
    Discipline Based Education Research | Evolution and development of the lateral line system | Urea cycle function and evolution

    My research focuses on effective ways to integrate scientific skills, authentic inquiry, and an understanding science into undergraduate curricula. I am working on three projects that incorporate scientific skills and inquiry into the classroom: 1) integration of biology and engineering through development of inquiry based cell culture technology and biomaterials lab modules, 2) study of the effective implementation of the CREATE approach to teaching the process of scientific inquiry through directed analysis of primary literature, and 3) the development/assessment of a scientific skills based transfer student course.

    I am investigating the evolution and embryonic development of lateral line system using threespine stickleback. We seek to understand how adult variation in the number and size of neuromast sensory organs are generated during embryonic development. I also am interested in the evolutionary conservation of urea cycle genes. We hypothesize the urea cycle genes function in  embryos prior to the formation of ammonia excretion pathways and protect the developing brain from the breakdown of yolk proteins. The conservation of urea cycle genes from fish to mammals allows us to study urea cycle disorders and the toxicity of hyperammonemia on brain development using the zebrafish model.

    Member of:
    American Association for the Advancement of Science
    American Society for Cell Biology
    Society for Developmental Biology

    Recent Academic Projects:
    I serve as the Program Director of the Cumberland County College Bridge to Rowan University NIH-sponsored Bridges to the Baccalaureate Program.

    Education/Academic qualification

    Doctor of Philosophy, doctorate

    Bachelor of Science, Bachelor, College of William and Mary


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