Keyphrases
RNA-dependent RNA Polymerase (RdRP)
66%
Bacterial RNA Polymerase
47%
Transcription Inhibition
37%
Depsipeptide
28%
Antibacterial Activity
23%
Binding Site
23%
RNA Polymerase Inhibitor
22%
Antibiotics
21%
Rifampin
20%
Pseudouridimycin
18%
Total Synthesis
18%
Natural Products
18%
Mycobacterium Tuberculosis (M. tb)
16%
Transcription Initiation
12%
Polymerase Switch
11%
Switch Region
11%
Dipeptide
11%
Lipiarmycin
10%
Myxopyronin
10%
Ripostatin
10%
Inhibitory Activity
10%
Resistance Factor
10%
Tuberculosis RNA
9%
Nucleoside-analog Inhibitor
9%
Pyrazole
9%
Fidaxomicin
9%
Antibacterial nucleosides
9%
Marine Streptomyces
9%
Novel Analogues
9%
New Targets
9%
Fitness Cost of Resistance
9%
Novel Antimicrobials
9%
Staphylococcus Aureus
9%
Frequency Spectrum
9%
Affinity Purification-mass Spectrometry (AP-MS)
9%
Solution Synthesis
9%
Antimicrobial
9%
Hydroxyproline
9%
Conformational Differences
9%
Cyclopeptides
9%
Activity Relationship
9%
Further Development
9%
Antimicrobial Activity
9%
Solid Phase
9%
Bridge Helix
9%
Antibacterial Drugs
8%
Cross-resistance
8%
RNA Polymerase Subunits
8%
Rifamycin
7%
Structure-activity Relationship
6%
Biochemistry, Genetics and Molecular Biology
RNA Polymerase
100%
Transcription
37%
Antibacterial Activity
18%
Depsipeptide
18%
Binding Site
16%
Mycobacterium Tuberculosis
13%
Transcription Initiation
11%
Dipeptide
11%
Nucleoside Analog
9%
Streptomyces
9%
Enzymatic Hydrolysis
9%
Mass Spectrometry
9%
Staphylococcus Aureus
9%
Crystal Structure
7%
Promoter Region
7%
Cross Resistance
7%
Pharmacology, Toxicology and Pharmaceutical Science
RNA Polymerase
41%
Bacterial RNA
31%
Antiinfective Agent
17%
Antibacterial Activity
12%
Antibiotics
11%
Fidaxomicin
11%
Dipeptide
11%
Depsipeptide
9%
Streptomyces
9%
Nucleoside Analog
9%
Epoxide
9%
Rifampicin
6%
