• 1202 Citations
  • 18 h-Index
1987 …2018
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Fingerprint Dive into the research topics where David Rotella is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Structure-Activity Relationship Medicine & Life Sciences
Phosphodiesterase 5 Inhibitors Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences
Serotonin Uptake Inhibitors Medicine & Life Sciences
Diamines Medicine & Life Sciences
Organic Chemistry Medicine & Life Sciences
Pharmaceutical Chemistry Medicine & Life Sciences
Phosphoric Diester Hydrolases Medicine & Life Sciences

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Research Output 1987 2018

1 Citation (Scopus)

Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis

Tummalapalli, S. R., Bhat, R., Chojnowski, A., Prorok, M., Kreiss, T., Goldberg, R., Canan, S., Hawryluk, N., Mortensen, D., Khetani, V., Zeldis, J., Siekierka, J. & Rotella, D., Mar 8 2018, In : ACS Medicinal Chemistry Letters. 9, 3, p. 210-214 5 p.

Montclair State University

Research output: Contribution to journalArticle

Filarial Elephantiasis
Structure-Activity Relationship
Protein Kinase Inhibitors
Heat-Shock Proteins
Protein Kinases
1 Citation (Scopus)

Expression, purification, and inhibition profile of dihydrofolate reductase from the filarial nematode Wuchereria bancrofti

Tobias, A. M., Toska, D., Lange, K., Eck, T., Bhat, R., Janson, C. A., Rotella, D. P., Gubler, U. & Goodey, N. M., May 2018, In : PLoS ONE. 13, 5, e0197173.

Montclair State University

Research output: Contribution to journalArticle

Wuchereria bancrofti
Tetrahydrofolate Dehydrogenase
Brugia malayi
Filariasis
Aminopterin

Comprehensive Medicinal Chemistry III

Chackalamannil, S., Rotella, D. & Ward, S. E., Jun 3 2017, The Future of Drug Discovery: Drug Discovery Technologies: In Silico Drug Discovery Tools: Experimental Adme and Toxicology: Cancer, Immunology and Inflammation, and Infectious Disease: Biologics Medicine: Cns, Pain, Metabolic Syndrome, Cardiovascular, Tissue Fibrosis and Urinary Incontinence: Case Histories in Recent Drug Discovery. Elsevier Inc., Vol. 1-8. p. 1-4369 4369 p.

Montclair State University

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmaceutical Chemistry
Biological Products
Medicine
Oligonucleotides
Nucleic Acid Heteroduplexes
4 Citations (Scopus)

Mechanism of inhibition of botulinum neurotoxin type A light chain by two quinolinol compounds

Minnow, Y. V. T., Goldberg, R., Tummalapalli, S. R., Rotella, D. & Goodey, N., Mar 15 2017, In : Archives of Biochemistry and Biophysics. 618, p. 15-22 8 p.

Montclair State University

Research output: Contribution to journalArticle

Hydroxyquinolines
Type A Botulinum Toxins
Light
Tetanus Toxin
Structure-Activity Relationship

Preface

Chackalamannil, S., Rotella, D. & Ward, S. E., Jun 3 2017, The Future of Drug Discovery: Drug Discovery Technologies: In Silico Drug Discovery Tools: Experimental Adme and Toxicology: Cancer, Immunology and Inflammation, and Infectious Disease: Biologics Medicine: Cns, Pain, Metabolic Syndrome, Cardiovascular, Tissue Fibrosis and Urinary Incontinence: Case Histories in Recent Drug Discovery. Elsevier Inc., Vol. 1-8. p. v-vi

Montclair State University

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript