Projects per year
My research interests are in two major areas: designing/characterizing peptides with specific functions and antimicrobial surfaces.
The majority of the research focuses on the development and characterization of antimicrobial peptides. These are short, cationic sequences that are highly effective, broad spectrum antimicrobials with low toxicity profiles. I study the chemical and amino-acid composition of these peptides and the role different amino acids play in the functional properties of these peptides. My lab also has a project focused on the design of peptides to interact with optically active porphyrins toward the development of novel materials for application in photovoltaic devices.
I also am interested in antimicrobial thin film coatings. In collaboration with the Departments of Physics & Astronomy and Electrical & Computer Engineering, my team has developed a series of coatings (patent pending) with a variety of antimicrobial and physical properties. The group focuses on the efficacy and mechanism of the antimicrobial coatings.
Doctor of Philosophy, doctorate
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- 2 Finished
6/1/22 → 9/30/22
Project: Other project
7/1/20 → 6/30/23
Project: Other project
Takahashi, H., Sovadinova, I., Yasuhara, K., Vemparala, S., Caputo, G. A. & Kuroda, K., May 1 2023, In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 15, 3, e1866.
Research output: Contribution to journal › Review article › peer-reviewOpen Access
Investigation of the Role of Hydrophobic Amino Acids on the Structure–Activity Relationship in the Antimicrobial Venom Peptide Ponericin L1Schifano, N. P. & Caputo, G. A., Oct 2022, In: Journal of Membrane Biology. 255, 4-5, p. 537-551 15 p.
Research output: Contribution to journal › Review article › peer-review
Peptide-assisted supramolecular polymerization of the anionic porphyrin meso-tetra(4-sulfonatophenyl)porphineKohn, E. M., Shirley, D. J., Hinds, N. M., Fry, H. C. & Caputo, G. A., Nov 2022, In: Peptide Science. 114, 6, e24288.
Research output: Contribution to journal › Article › peer-reviewOpen Access
Caputo, G. & Chattopadhyay, A., Oct 2022, In: Journal of Membrane Biology. 255, 4-5, p. 373 1 p.
Research output: Contribution to journal › Editorial › peer-reviewOpen Access
Selective Detection and Characterization of Small Cysteine-Containing Peptides with Cluster-Modified Nanopore SensingGhimire, M. L., Cox, B. D., Winn, C. A., Rockett, T. W., Schifano, N. P., Slagle, H. M., Gonzalez, F., Bertino, M. F., Caputo, G. A. & Reiner, J. E., Oct 25 2022, In: ACS Nano. 16, 10, p. 17229-17241 13 p.
Research output: Contribution to journal › Article › peer-review