Projects per year
Personal profile
Research interests
Research Expertise:
Analytical Chemistry | Liquid Chromatography | Microfluidics
My research background focuses on the fundamental development of liquid chromatography (LC) columns in capillaries and microfluidic devices. LC columns are at the heart of many analytical separation techniques across pharmaceutical, environmental, and biomedical research projects. Early work focused on the physical structure of the packed chromatographic bed inside a fused silica capillary and led to strategies that could be used to pack more efficient columns in capillaries and also miniaturized microfluidic devices. Other interests have included understanding the physical processes beyond bed structure that impact column performance (included extra-column effects and frictional heating) and applying LC and mass spectrometry (MS) instrumentation to solve analytical problems in neuroscience and molecular physiology.
Honors and Awards:
2017 Eastern Michigan University Young Alumnus Award
NIH NRSA Individual Postdoctoral Fellowship Award (F32- EB019800)
HPLC 2013 Csaba Horváth Top Young Scientist Award
Member of:
American Chemical Society (www.acs.org)
California Separation Science Society (www.casss.org)
Chromatography Forum of Delaware Valley (www.cfdv.org)
Education/Academic qualification
Doctor of Philosophy, doctorate
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Sensor-Like LC-MS Platform for Rapid Online Monitoring of Metabolites in Biological Systems
Grinias, J. (PI)
National Institutes of Health (NIH)
9/15/24 → 6/30/29
Project: Research project
-
Detection of PTSD Biomarkers in Portable LC/MS System: Phase II
Grinias, J. (PI)
12/18/23 → 3/26/26
Project: Other project
-
CAREER: Parallel Two-Dimensional Liquid Chromatography Utilizing Capillary Columns
Grinias, J. (PI)
National Science Foundation (NSF)
1/1/21 → 12/31/25
Project: Other project
-
Comparison of experimental and simulated separation performance in capillary tube-in-manifold devices
Piccolo, C., Keller, M., Czarnecki, D. J., Austin, T., Shelver, G. & Grinias, J. P., Nov 8 2024, In: Journal of Chromatography A. 1736, 465428.Research output: Contribution to journal › Article › peer-review
Open Access -
Considerations for method development and method translation in capillary liquid chromatography: A tutorial
Hanson, E. K., Foster, S. W., Piccolo, C. & Grinias, J. P., Nov 2024, In: Journal of Chromatography Open. 6, 100190.Research output: Contribution to journal › Article › peer-review
Open Access -
High-Throughput Capillary Liquid Chromatography Using a Droplet Injection and Application to Reaction Screening
Xin, Y., Foster, S. W., Makey, D. M., Parker, D., Bradow, J., Wang, X., Berritt, S., Mongillo, R., Grinias, J. P. & Kennedy, R. T., Mar 19 2024, In: Analytical Chemistry. 96, 11, p. 4693-4701 9 p.Research output: Contribution to journal › Article › peer-review
-
Repetitive mild traumatic brain injury impairs norepinephrine system function and psychostimulant responsivity
Horvat, L., Foschini, A., Grinias, J. P., Waterhouse, B. D. & Devilbiss, D. M., Sep 15 2024, In: Brain research. 1839, 149040.Research output: Contribution to journal › Article › peer-review
-
Supercritical fluid chromatography- Nanospray ionization-mass spectrometry (SFC-nSI-MS)
Mostafa, M. E., Grinias, J. P. & Edwards, J. L., Nov 8 2024, In: Journal of Chromatography A. 1736, 465377.Research output: Contribution to journal › Article › peer-review