Projects per year
Personal profile
Research interests
Research Expertise:
Analytical Chemistry | Liquid Chromatography | Microfluidics
My research background focuses on the fundamental development of liquid chromatography (LC) columns in capillaries and microfluidic devices. LC columns are at the heart of many analytical separation techniques across pharmaceutical, environmental, and biomedical research projects. Early work focused on the physical structure of the packed chromatographic bed inside a fused silica capillary and led to strategies that could be used to pack more efficient columns in capillaries and also miniaturized microfluidic devices. Other interests have included understanding the physical processes beyond bed structure that impact column performance (included extra-column effects and frictional heating) and applying LC and mass spectrometry (MS) instrumentation to solve analytical problems in neuroscience and molecular physiology.
Honors and Awards:
2017 Eastern Michigan University Young Alumnus Award
NIH NRSA Individual Postdoctoral Fellowship Award (F32- EB019800)
HPLC 2013 Csaba Horváth Top Young Scientist Award
Member of:
American Chemical Society (www.acs.org)
California Separation Science Society (www.casss.org)
Chromatography Forum of Delaware Valley (www.cfdv.org)
Education/Academic qualification
Doctor of Philosophy, doctorate
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Sensor-Like LC-MS Platform for Rapid Online Monitoring of Metabolites in Biological Systems
Grinias, J. (PI)
National Institutes of Health (NIH)
9/15/24 → 6/30/29
Project: Research
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Detection of PTSD Biomarkers in Portable LC/MS System: Phase II
Grinias, J. (PI)
12/18/23 → 3/26/26
Project: Other
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Compact Liquid Chromatography for Routine Screening in Drug Treatment Centers
Grinias, J. (PI)
9/1/22 → 4/30/26
Project: Other
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A rapid reversed-phase liquid chromatography method for the determination of individual monoclonal antibody content in a co-formulated drug product
Swoyer, M. R., Parker, D., Felix, L. E., Dipaolo, B. R., Grinias, J. P. & Godinho, J. M., Dec 6 2025, In: Journal of Chromatography A. 1764, 466501.Research output: Contribution to journal › Article › peer-review
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Development of a Direct Sampling Module for Compact Capillary Liquid Chromatography
Doupsas, N., Morse, M., Powell, M., Alimuddin, M., Braganza, J., Elleraas, J., Wang, W., Yanovsky, A., Lee, M. L., Richardson, P. F. & Grinias, J. P., Oct 2025, In: Journal of Separation Science. 48, 10, e70311.Research output: Contribution to journal › Article › peer-review
Open Access -
The ACS Division of Analytical Chemistry Awards Program: Honoring Our Recent Awardees
Grinias, J. P., Garcia, B. A., Phinney, K. W. & Destino, J. F., Oct 14 2025, In: Analytical Chemistry. 97, 40, p. 21761-21762 2 p.Research output: Contribution to journal › Editorial › peer-review
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Comparison of experimental and simulated separation performance in capillary tube-in-manifold devices
Piccolo, C., Keller, M., Czarnecki, D. J., Austin, T., Shelver, G. & Grinias, J. P., Nov 8 2024, In: Journal of Chromatography A. 1736, 465428.Research output: Contribution to journal › Article › peer-review
Open Access -
Considerations for method development and method translation in capillary liquid chromatography: A tutorial
Hanson, E. K., Foster, S. W., Piccolo, C. & Grinias, J. P., Nov 2024, In: Journal of Chromatography Open. 6, 100190.Research output: Contribution to journal › Article › peer-review
Open Access