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Dive into the research topics where Joel Freundlich is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A Preclinical Program for Targeting Mycobacterium tuberculosis KasA
Freundlich, J. (CoPI)
National Institute of Allergy and Infectious Diseases
8/10/21 → 7/31/25
Project: Research
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Novel Dual-Stage Antimalarials: Machine learning prediction, validation and evolution
Freundlich, J. (PI) & Derbyshire, E. R. (CoPI)
National Institute of Allergy and Infectious Diseases
7/3/23 → 6/30/24
Project: Research
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Synthesizability-constrained expansion and multi-objective evolution of antitubercular compounds
Coley, C. C. W. (CoPI) & Freundlich, J. (CoPI)
National Institute of Allergy and Infectious Diseases
3/18/22 → 2/29/24
Project: Research
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Structure-guided optimization of an in vivo active small molecule antitubercular targeting KasA
Ekins, S. (PI) & Freundlich, J. (CoPI)
National Institute of Allergy and Infectious Diseases
2/7/18 → 7/31/19
Project: Research project
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A multiplex method for rapidly identifying viral protease inhibitors
Hong, S. J., Resnick, S. J., Iketani, S., Cha, J. W., Albert, B. A., Fazekas, C. T., Chang, C. W., Liu, H., Dagan, S., Abagyan, M. R., Fajtová, P., Culbertson, B., Brace, B., Reddem, E. R., Forouhar, F., Glickman, J. F., Balkovec, J. M., Stockwell, B. R., Shapiro, L. & O’Donoghue, A. J. & 4 others, , Feb 3 2025, In: Molecular Systems Biology. 21, 2, p. 158-172 15 p., 2016.Hackensack Meridian School of Medicine
Research output: Contribution to journal › Article › peer-review
Open Access -
Evolution of Small Molecule Inhibitors of Mycobacterium tuberculosis Menaquinone Biosynthesis
Sharma, P., Jiang, Q., Li, S. G., Ocke, E., Tsotetsi, K., Sukheja, P., Singh, P., Suryavanshi, S., Morrison, E., Thadkapally, S., Russo, R., Penalva-Lopez, S., Cangialosi, J., Sharma, V., Johnson, K., Sarathy, J. P., Nelson, A. M., Park, S., Zimmerman, M. D. & Alland, D. & 2 others, , Mar 13 2025, In: Journal of medicinal chemistry. 68, 5, p. 5774-5803 30 p.Hackensack Meridian School of Medicine
Research output: Contribution to journal › Article › peer-review
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Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O-Acetyl-l-serine Sulfhydrylase (CysK)
Pederick, J. L., Vandborg, B. C., George, A., Bovermann, H., Boyd, J. M., Freundlich, J. S. & Bruning, J. B., Jan 10 2025, In: ACS infectious diseases. 11, 1, p. 238-248 11 p.Research output: Contribution to journal › Article › peer-review
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A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting
Chain, C., Sheehan, J. P., Xu, X., Ghaffari, S., Godbole, A., Kim, H., Freundlich, J. S., Rabinowitz, J. D. & Gitai, Z., May 2024, In: Nature Microbiology. 9, 5, p. 1207-1219 13 p.Princeton University, Rutgers, The State University
Research output: Contribution to journal › Article › peer-review
Open Access -
Dynamic PET reveals compartmentalized brain and lung tissue antibiotic exposures of tuberculosis drugs
Chen, X., Arun, B., Nino-Meza, O. J., Sarhan, M. O., Singh, M., Jeon, B., Mane, K., Shah, M., Tucker, E. W., Carroll, L. S., Freundlich, J. S., Peloquin, C. A., Ivaturi, V. D. & Jain, S. K., Dec 2024, In: Nature communications. 15, 1, 6657.Research output: Contribution to journal › Article › peer-review
Open Access