• 5055 Citations
  • 34 h-Index
1973 …2018
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Fingerprint Dive into the research topics where John Siekierka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Tacrolimus Medicine & Life Sciences
Tacrolimus Binding Proteins Medicine & Life Sciences
p38 Mitogen-Activated Protein Kinases Medicine & Life Sciences
Immunosuppressive Agents Medicine & Life Sciences
Eukaryotic Initiation Factor-2 Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Sirolimus Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1973 2018

Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis

Tummalapalli, S. R., Bhat, R., Chojnowski, A., Prorok, M., Kreiss, T., Goldberg, R., Canan, S., Hawryluk, N., Mortensen, D., Khetani, V., Zeldis, J., Siekierka, J. & Rotella, D., Mar 8 2018, In : ACS Medicinal Chemistry Letters. 9, 3, p. 210-214 5 p.

Montclair State University

Research output: Contribution to journalArticle

Filarial Elephantiasis
Structure-Activity Relationship
Protein Kinase Inhibitors
Heat-Shock Proteins
Protein Kinases
1 Citation (Scopus)

Expression, purification and enzymatic characterization of Brugia malayi dihydrofolate reductase

Perez-Abraham, R., Sanchez, K. G., Alfonso, M., Gubler, U., Siekierka, J. & Goodey, N., Dec 1 2016, In : Protein Expression and Purification. 128, p. 81-85 5 p.

Montclair State University

Research output: Contribution to journalArticle

Brugia malayi
Tetrahydrofolate Dehydrogenase
Neglected Diseases
Filarial Elephantiasis
Folic Acid Antagonists
15 Citations (Scopus)

Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication

Brumlik, M. J., Nkhoma, S., Kious, M. J., Thompson, G. R., Patterson, T. F., Siekierka, J., Anderson, T. J. C. & Curiel, T. J., Jun 1 2011, In : Experimental Parasitology. 128, 2, p. 170-175 6 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Plasmodium falciparum
Protein Kinase Inhibitors
Chloroquine
Encephalitozoon cuniculi
11 Citations (Scopus)

The role of a Brugia malayi p38 MAP kinase ortholog (Bm-MPK1) in parasite anti-oxidative stress responses

Patel, A., Chojnowski, A. N., Gaskill, K., De Martini, W., Goldberg, R. L. & Siekierka, J. J., Apr 1 2011, In : Molecular and Biochemical Parasitology. 176, 2, p. 90-97 8 p.

Montclair State University

Research output: Contribution to journalArticle

Brugia malayi
p38 Mitogen-Activated Protein Kinases
Parasites
Oxidative Stress
Reactive Oxygen Species
Apicomplexa
Trypanosoma
Antiparasitic Agents
Parasitic Diseases
Protein Kinases