• 5067 Citations
  • 34 h-Index
1973 …2018
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Research Output 1973 2018

2018
1 Citation (Scopus)

Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis

Tummalapalli, S. R., Bhat, R., Chojnowski, A., Prorok, M., Kreiss, T., Goldberg, R., Canan, S., Hawryluk, N., Mortensen, D., Khetani, V., Zeldis, J., Siekierka, J. & Rotella, D., Mar 8 2018, In : ACS Medicinal Chemistry Letters. 9, 3, p. 210-214 5 p.

Montclair State University

Research output: Contribution to journalArticle

Filarial Elephantiasis
Structure-Activity Relationship
Protein Kinase Inhibitors
Heat-Shock Proteins
Protein Kinases
2016
1 Citation (Scopus)

Expression, purification and enzymatic characterization of Brugia malayi dihydrofolate reductase

Perez-Abraham, R., Sanchez, K. G., Alfonso, M., Gubler, U., Siekierka, J. & Goodey, N., Dec 1 2016, In : Protein Expression and Purification. 128, p. 81-85 5 p.

Montclair State University

Research output: Contribution to journalArticle

Brugia malayi
Tetrahydrofolate Dehydrogenase
Neglected Diseases
Filarial Elephantiasis
Folic Acid Antagonists
2011
15 Citations (Scopus)

Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication

Brumlik, M. J., Nkhoma, S., Kious, M. J., Thompson, G. R., Patterson, T. F., Siekierka, J. J., Anderson, T. J. C. & Curiel, T. J., Jun 1 2011, In : Experimental Parasitology. 128, 2, p. 170-175 6 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Plasmodium falciparum
Protein Kinase Inhibitors
Chloroquine
Encephalitozoon cuniculi
11 Citations (Scopus)

The role of a Brugia malayi p38 MAP kinase ortholog (Bm-MPK1) in parasite anti-oxidative stress responses

Patel, A., Chojnowski, A. N., Gaskill, K., De Martini, W., Goldberg, R. L. & Siekierka, J. J., Apr 1 2011, In : Molecular and Biochemical Parasitology. 176, 2, p. 90-97 8 p.

Montclair State University

Research output: Contribution to journalArticle

Brugia malayi
p38 Mitogen-Activated Protein Kinases
Parasites
Oxidative Stress
Reactive Oxygen Species
2010
15 Citations (Scopus)
Apicomplexa
Trypanosoma
Antiparasitic Agents
Parasitic Diseases
Protein Kinases
2008
4 Citations (Scopus)

Tranilast: A pharmaceutical candidate for reduction of adhesions using a novel approach

Petrilli, J., Wadsworth, S., Cooper, K., Rodgers, K. E., Siekierka, J. & DiZerega, G. S., Jul 1 2008, In : Seminars in Reproductive Medicine. 26, 4, p. 341-348 8 p.

Montclair State University

Research output: Contribution to journalReview article

Architectural Accessibility
Pharmaceutical Preparations
Laparoscopy
Gels
Equipment and Supplies
2007
20 Citations (Scopus)

Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection

Wei, S., Daniel, B. J., Brumlik, M. J., Burow, M. E., Zou, W., Khan, I. A., Wadsworth, S., Siekierka, J. & Curiel, T. J., Dec 1 2007, In : Antimicrobial agents and chemotherapy. 51, 12, p. 4324-4328 5 p.

Montclair State University

Research output: Contribution to journalArticle

Encephalitozoon cuniculi
Toxoplasma
p38 Mitogen-Activated Protein Kinases
Protein Kinase Inhibitors
Mitogen-Activated Protein Kinases
2006
13 Citations (Scopus)

A multiplexed proteomics approach to differentiate neurite outgrowth patterns

Liu, T., D'mello, V., Deng, L., Hu, J., Ricardo, M., Pan, S., Lu, X., Wadsworth, S., Siekierka, J., Birge, R. & Li, H., Nov 15 2006, In : Journal of Neuroscience Methods. 158, 1, p. 22-29 8 p.

Rutgers, The State University, Montclair State University

Research output: Contribution to journalArticle

Nerve Growth Factor
Proteomics
Immunophilins
Organogenesis
Spinal Ganglia
6 Citations (Scopus)

Effects of drug combinations on smooth muscle cell proliferation: An isobolographic analysis

Parry, T. J., Thyagarajan, R., Argentieri, D., Falotico, R., Siekierka, J. & Tallarida, R. J., Feb 17 2006, In : European Journal of Pharmacology. 532, 1-2, p. 38-43 6 p.

Montclair State University

Research output: Contribution to journalArticle

Drug Combinations
Sirolimus
Smooth Muscle Myocytes
Cell Proliferation
Cladribine
7 Citations (Scopus)

Inhibitors of unactivated p38 MAP kinase

Bullington, J., Argentieri, D., Averill, K., Carter, D., Cavender, D., Fahmy, B., Fan, X., Hall, D., Heintzelman, G., Jackson, P., Leung, W. P., Li, X., Ling, P., Olini, G., Razler, T., Reuman, M., Rupert, K., Russell, R., Siekierka, J., Wadsworth, S. & 3 others, Wolff, R., Xiang, B. & Zhang, Y. M., Dec 1 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 23, p. 6102-6106 5 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Phosphotransferases
MAP Kinase Signaling System
In Vitro Techniques
2005
99 Citations (Scopus)

Drug-eluting stents: Sirolimus and paclitaxel differentially affect cultured cells and injured arteries

Parry, T. J., Brosius, R., Thyagarajan, R., Carter, D., Argentieri, D., Falotico, R. & Siekierka, J., Nov 7 2005, In : European Journal of Pharmacology. 524, 1-3, p. 19-29 11 p.

Montclair State University

Research output: Contribution to journalArticle

Drug-Eluting Stents
Sirolimus
Paclitaxel
Cultured Cells
Arteries
38 Citations (Scopus)

HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation

Muthumani, K., Choo, A. Y., Hwang, D. S., Premkumar, A., Dayes, N. S., Harris, C., Green, D. R., Wadsworth, S. A., Siekierka, J. & Weiner, D. B., Sep 15 2005, In : Blood. 106, 6, p. 2059-2068 10 p.

Montclair State University

Research output: Contribution to journalArticle

Fas Ligand Protein
Transcription Factor AP-1
p38 Mitogen-Activated Protein Kinases
Viruses
HIV-1
2004
29 Citations (Scopus)

A novel role for the immunophilin FKBP52 in copper transport

Sanokawa-Akakura, R., Dai, H., Akakura, S., Weinstein, D., Fajardo, J. E., Lang, S. E., Wadsworth, S., Siekierka, J. & Birge, R., Jul 2 2004, In : Journal of Biological Chemistry. 279, 27, p. 27845-27848 4 p.

Rutgers, The State University, Montclair State University

Research output: Contribution to journalArticle

Immunophilins
Tacrolimus Binding Proteins
Copper
cis-trans-Isomerases
Peptidylprolyl Isomerase
34 Citations (Scopus)

A role for schwann cells in the neuroregenerative effects of a non-immunosuppressive FK506 derivative, JNJ460

Birge, R., Wadsworth, S., Akakura, R., Abeysinghe, H., Kanojia, R., Macielag, M., Desbarats, J., Escalante, M., Singh, K., Sundarababu, S., Parris, K., Childs, G., August, A., Siekierka, J. & Weinstein, D. E., Jan 1 2004, In : Neuroscience. 124, 2, p. 351-366 16 p.

Rutgers, The State University, Montclair State University

Research output: Contribution to journalArticle

Schwann Cells
Tacrolimus
Immunophilins
Neurons
Ligands
31 Citations (Scopus)

Suppression of HIV-1 viral replication and cellular pathogenesis by a novel p38/JNK kinase inhibitor

Muthumani, K., Wadsworth, S. A., Dayes, N. S., Hwang, D. S., Choo, A. Y., Abeysinghe, H. R., Siekierka, J. & Weiner, D. B., Mar 26 2004, In : AIDS. 18, 5, p. 739-748 10 p.

Montclair State University

Research output: Contribution to journalArticle

MAP Kinase Kinase 4
HIV-1
HIV Infections
T-Lymphocytes
Protein-Serine-Threonine Kinases
2003
193 Citations (Scopus)

Imidazopyrimidines, potent inhibitors of p38 MAP kinase

Rupert, K. C., Henry, J. R., Dodd, J. H., Wadsworth, S. A., Cavender, D. E., Olini, G. C., Fahmy, B. & Siekierka, J. J., Feb 1 2003, In : Bioorganic and Medicinal Chemistry Letters. 13, 3, p. 347-350 4 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cytokines
Interleukin-1
Crohn Disease
Rheumatoid Arthritis
2002
20 Citations (Scopus)

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells

Tao, L., Wadsworth, S., Mercer, J., Mueller, C., Lynn, K., Siekierka, J. & August, A., Apr 1 2002, In : Biochemical Journal. 363, 1, p. 175-182 8 p.

Montclair State University

Research output: Contribution to journalArticle

T-cells
Lymphocytes
Protein-Serine-Threonine Kinases
Phosphotransferases
T-Lymphocytes
2001
46 Citations (Scopus)

Kinetics of small molecule inhibitor binding to p38 kinase

Thurmond, R. L., Wadsworth, S. A., Schafer, P. H., Zivin, R. A. & Siekierka, J., Dec 3 2001, In : European Journal of Biochemistry. 268, 22, p. 5747-5754 8 p.

Montclair State University

Research output: Contribution to journalArticle

Phosphotransferases
p38 Mitogen-Activated Protein Kinases
Molecules
Kinetics
Association reactions
1999
135 Citations (Scopus)

Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

Kanakaraj, P., Ngo, K., Wu, Y., Angulo, A., Ghazal, P., Harris, C. A., Siekierka, J. J., Peterson, P. A. & Fung-Leung, W. P., Apr 5 1999, In : Journal of Experimental Medicine. 189, 7, p. 1129-1138 10 p.

Montclair State University

Research output: Contribution to journalArticle

Interleukin-1 Receptor-Associated Kinases
Natural Killer T-Cells
Interleukin-18
Interferons
Th1 Cells
84 Citations (Scopus)
Th2 Cells
p38 Mitogen-Activated Protein Kinases
Interleukin-4
T-Lymphocytes
Th1 Cells
148 Citations (Scopus)

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase

Wadsworth, S. A., Cavender, D. E., Beers, S. A., Lalan, P., Schafer, P. H., Malloy, E. A., Wu, W., Fahmy, B., Olini, G. C., Davis, J. E., Pellegrino-Gensey, J. L., Wachter, M. P. & Siekierka, J. J., Nov 1 1999, In : Journal of Pharmacology and Experimental Therapeutics. 291, 2, p. 680-687 8 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Tumor Necrosis Factor-alpha
Inhibitory Concentration 50
T-Lymphocytes
Monocytes
63 Citations (Scopus)

T cell activation signals up-regulate p38 mitogen-activated protein kinase activity and induce TNF-α production in a manner distinct from LPS activation of monocytes

Schafer, P. H., Wang, L., Wadsworth, S. A., Davis, J. E. & Siekierka, J., Jan 15 1999, In : Journal of Immunology. 162, 2, p. 659-668 10 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Monocytes
Up-Regulation
T-Lymphocytes
Clone Cells
1998
75 Citations (Scopus)

6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

Henry, J. R., Rupert, K. C., Dodd, J. H., Turchi, I. J., Wadsworth, S. A., Cavender, D. E., Fahmy, B., Olini, G. C., Davis, J. E., Lee Pellegrino-Gensey, J., Schafer, P. H. & Siekierka, J., Oct 23 1998, In : Journal of Medicinal Chemistry. 41, 22, p. 4196-4198 3 p.

Montclair State University

Research output: Contribution to journalLetter

115 Citations (Scopus)

Detergent-salt resistance of LAP2α in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics

Dechat, T., Gotzmann, J., Stockinger, A., Harris, C. A., Talle, M. A., Siekierka, J. J. & Foisner, R., Aug 17 1998, In : EMBO Journal. 17, 16, p. 4887-4902 16 p.

Montclair State University

Research output: Contribution to journalArticle

Phosphorylation
Interphase
Chromosomes
Detergents
Salts
169 Citations (Scopus)

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

Kanakaraj, P., Schafer, P. H., Cavender, D. E., Wu, Y., Ngo, K., Grealish, P. F., Wadsworth, S. A., Peterson, P. A., Siekierka, J., Harris, C. A. & Fung-Leung, W. P., Jun 15 1998, In : Journal of Experimental Medicine. 187, 12, p. 2073-2079 7 p.

Montclair State University

Research output: Contribution to journalArticle

Interleukin-1 Receptor-Associated Kinases
Interleukin-1
Interleukin-6
Fibroblasts
JNK Mitogen-Activated Protein Kinases

Irak requirement for optimal induction by IL-I of multiple signaling pathways

Kanakaraji, P., Schafer, P. H., Cavender, D., Ngo, K., Wul, Y., Grealish, F. F., Wadsworth, S. A., Peterson, P. A., Siekierka, J., Harris, C. A. & Fung-Leungl, W. P., Dec 1 1998, In : FASEB Journal. 12, 8

Montclair State University

Research output: Contribution to journalArticle

Interleukin-1 Receptor-Associated Kinases
Interleukin-1
Interleukin-1 Receptors
Drosophila
Chemical activation
45 Citations (Scopus)

Potent inhibitors of the MAP kinase p38

Henry, J. R., Rupert, K. C., Dodd, J. H., Turchi, I. J., Wadsworth, S. A., Cavender, D. E., Schafer, P. H. & Siekierka, J., Dec 1 1998, In : Bioorganic and Medicinal Chemistry Letters. 8, 23, p. 3335-3340 6 p.

Montclair State University

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Interleukin-1
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Cytokines
17 Citations (Scopus)

The development of novel and selective p56(lck) tyrosine kinase inhibitors

Bullington, J. L., Cameron, J. C., Davis, J. E., Dodd, J. H., Harris, C. A., Henry, J. R., Pellegrino-Gensey, J. L., Rupert, K. C. & Siekierka, J., Sep 22 1998, In : Bioorganic and Medicinal Chemistry Letters. 8, 18, p. 2489-2494 6 p.

Montclair State University

Research output: Contribution to journalArticle

Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Protein-Tyrosine Kinases
Signal transduction
T-cells
T-Cell Antigen Receptor

Yeast immunophilins: Purification and assay of yeast FKBP12

Wiederrecht, G. & Siekierka, J., Jan 1 1998, In : Methods in enzymology. 290, p. 74-84 11 p.

Montclair State University

Research output: Contribution to journalArticle

1997
23 Citations (Scopus)

Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45

Beers, S. A., Malloy, E. A., Wu, W., Wachter, M. P., Gunnia, U., Cavender, D., Harris, C., Davis, J., Brosius, R., Pellegrino-Gensey, J. L. & Siekierka, J., Dec 1 1997, In : Bioorganic and Medicinal Chemistry. 5, 12, p. 2203-2211 9 p.

Montclair State University

Research output: Contribution to journalArticle

Catalytic Domain
Kinetics
Acids
Enzymes
phosphonic acid

T cell activation signals upregulate p38 map k1nase activity

Wang, L., Schäfer, P. H., Davis, J. K., Wads Worth, S. A. & Siekierka, J. J., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1167

Montclair State University

Research output: Contribution to journalArticle

T-cells
Up-Regulation
Chemical activation
T-Lymphocytes
Mitogen-Activated Protein Kinases
1996

Editorial

Siekierka, J., Apr 1 1996, In : Methods. 9, 2, 1 p.

Montclair State University

Research output: Contribution to journalEditorial

1 Citation (Scopus)
Immunophilins
Sirolimus
Cell Cycle
Cells
Apoptosis
1995
71 Citations (Scopus)

Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO β to rat lamin-associated polypeptide 2

Harris, C. A., Andryuk, P. J., Cline, S. W., Mathew, S., Siekierka, J. & Goldstein, G., Jul 20 1995, In : Genomics. 28, 2, p. 198-205 8 p.

Montclair State University

Research output: Contribution to journalArticle

Thymopoietins
Lamins
Peptides
Genes
Exons
1994
10 Citations (Scopus)

Alkyl ether derivatives of the FK-506 related, immunosuppressive macrolide L-683,742 (C31-O-desmethyl ascomycin)

Goulet, M. T., Hodkey, D. W., Staruch, M. J., Dumont, F. J., Lin, S., Hung, S. H. Y., Siekierka, J. J. & Wyvratt, M. J., 1994, In : Bioorganic and Medicinal Chemistry Letters. 4, 7, p. 927-930 4 p.

Montclair State University

Research output: Contribution to journalArticle

Macrolides
Tacrolimus
Immunosuppressive Agents
Ether
Derivatives
8 Citations (Scopus)
Tacrolimus
Sirolimus
Immunosuppressive Agents
Signal Transduction
T-Lymphocytes
98 Citations (Scopus)

Three distinct human thymopoietins are derived from alternatively spliced mRNAs

Harris, C. A., Andryuk, P. J., Cline, S., Karen Chan, H., Natarajan, A., Siekierka, J. & Goldstein, G., Jul 5 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 14, p. 6283-6287 5 p.

Montclair State University

Research output: Contribution to journalArticle

Thymopoietins
Messenger RNA
Thymus Gland
T-Lymphocytes
Proteins
1993
162 Citations (Scopus)

Rapamycin-induced inhibition of p34(cdc2) kinase activation is associated with G1/S-phase growth arrest in T lymphocytes

Morice, W. G., Brunn, G. J., Wiederrecht, G., Siekierka, J. J. & Abraham, R. T., Jan 1 1993, In : Journal of Biological Chemistry. 268, 5, p. 3734-3738 5 p.

Montclair State University

Research output: Contribution to journalArticle

T-cells
G1 Phase
Sirolimus
S Phase
Phosphotransferases
130 Citations (Scopus)

Rapamycin inhibition of interleukin-2-dependent p33(cdk2) and p34(cdc2) kinase activation in T lymphocytes

Morice, W. G., Wiederrecht, G., Brunn, G. J., Siekierka, J. J. & Abraham, R. T., Jan 1 1993, In : Journal of Biological Chemistry. 268, 30, p. 22737-22745 9 p.

Montclair State University

Research output: Contribution to journalArticle

T-cells
Cyclin A
Sirolimus
Cyclin E
Interleukin-2
1992
89 Citations (Scopus)

Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex

Wiederrecht, G., Hung, S., Chan, H. K., Marcy, A., Martin, M., Calaycay, J., Boulton, D., Sigal, N., Kincaid, R. L. & Siekierka, J. J., Nov 11 1992, In : Journal of Biological Chemistry. 267, 30, p. 21753-21760 8 p.

Montclair State University

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Tacrolimus Binding Protein 1A
Tacrolimus
Molecular Weight
Molecular weight
73 Citations (Scopus)

FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond

Siekierka, J. J. & Sigal, N. H., 1992, In : Current Opinion in Immunology. 4, 5, p. 548-552 5 p.

Montclair State University

Research output: Contribution to journalArticle

Calcineurin
Tacrolimus
Immunosuppressive Agents
Cyclosporine
Biochemical Phenomena
20 Citations (Scopus)

Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein

Wiederrecht, G., Martin, M. M., Sigal, N. H. & Siekierka, J. J., May 29 1992, In : Biochemical and Biophysical Research Communications. 185, 1, p. 298-303 6 p.

Montclair State University

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Complementary DNA
Thymus
Sirolimus
Gene Library
221 Citations (Scopus)

The immunosuppressive and toxic effects of FK-506 are mechanistically related: Pharmacology of a novel antagonist of FK-506 and rapamycin

Dumont, F. J., Staruch, M. J., Koprak, S. L., Siekierka, J. J., Lin, C. S., Harrison, R., Sewell, T., Kindt, V. M., Beattie, T. R., Wyvratt, M. & Sigal, N. H., Sep 1 1992, In : Journal of Experimental Medicine. 176, 3, p. 751-760 10 p.

Montclair State University

Research output: Contribution to journalArticle

Poisons
Tacrolimus
Sirolimus
Immunosuppressive Agents
Carrier Proteins
46 Citations (Scopus)

Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2

Nielsen, J. B., Foor, F., Siekierka, J. J., Hsu, M. J., Ramadan, N., Morin, N., Shafiee, A., Dahl, A. M., Brizuela, L., Chrebet, G., Bostian, K. A. & Parent, S. A., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 16, p. 7471-7475 5 p.

Montclair State University

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Tacrolimus
cis-trans-Isomerases
Sirolimus
Yeasts
106 Citations (Scopus)

FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes

Lin, C. S., Boltz, R. C., Siekierka, J. J. & Sigal, N. H., Apr 1 1991, In : Cellular Immunology. 133, 2, p. 269-284 16 p.

Montclair State University

Research output: Contribution to journalArticle

Tacrolimus
Cyclosporine
Signal Transduction
T-Lymphocytes
Ionomycin
76 Citations (Scopus)
Tacrolimus Binding Proteins
Cyclophilins
Saccharomyces cerevisiae
Immunosuppressive Agents
Amino Acids
9 Citations (Scopus)

FKBP, the binding protein for the immunosuppressive drug, FK-506, is not an inhibitor of protein kinase C activity

Cryan, J., Hung, S. H. Y., Wiederrecht, G., Sigal, N. H. & Siekierka, J. J., Oct 31 1991, In : Biochemical and Biophysical Research Communications. 180, 2, p. 846-852 7 p.

Montclair State University

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Tacrolimus
Immunosuppressive Agents
Protein Kinase C
Carrier Proteins
57 Citations (Scopus)

Inhibition of human T-cell activation by FK 506, rapamycin, and cyclosporine A

Sigal, N. H., Lin, C. S. & Siekierka, J. J., May 17 1991, In : Transplantation Proceedings. 23, 2 SUPPL. 2, p. 1-5 5 p.

Montclair State University

Research output: Contribution to journalArticle

215 Citations (Scopus)

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

Sigal, N. H., Dumont, F., Durette, P., Siekierka, J. J., Peterson, L., Rich, D. H., Dunlap, B. E., Staruch, M. J., Melino, M. R., Koprak, S. L., Williams, D., Witzel, B. & Pisano, J. M., Jan 1 1991, In : Journal of Experimental Medicine. 173, 3, p. 619-628 10 p.

Montclair State University

Research output: Contribution to journalArticle

Peptidylprolyl Isomerase
Cyclophilins
Immunosuppressive Agents
Cyclosporine
Lymphocytes