Keyphrases
3-Aminopyridine
50%
Akt Kinase
100%
Alkylation
100%
Arylation
100%
Biocatalytic
100%
Biocatalytic Reduction
16%
Bromo
50%
Chemoselective
50%
Chloropyridines
50%
Chromatography-free Synthesis
50%
Continuous Processing
50%
Cyclobutane
50%
Deprotonation
50%
Dianion
50%
Diastereomers
66%
Ebastine
16%
Ester Hydrolysis
50%
Ether
100%
Excellent Yields
16%
Formylation
50%
Fragment Coupling
50%
Glucokinase Activator
100%
Halogen-metal Exchange
50%
High Pressure
50%
High Temperature
50%
Highly Selective
50%
Hydrazine
50%
Kilogram-scale Synthesis
100%
Kinase Inhibitor
100%
Large-scale Synthesis
100%
Methyl
50%
Minimum number
50%
O-alkylation
50%
O-arylation
50%
Operation number
50%
Overall Yield
50%
Piperidone
100%
Practical Preparation
50%
Process Development
50%
Process-related Impurities
50%
Processing Mode
50%
Protecting Groups
16%
Protective Group
50%
Quantitative Yield
16%
Reaction Yield
50%
Reductive Etherification
100%
Robust Synthesis
50%
Suzuki
50%
Target Molecule
50%
Triethylsilane
16%
Chemistry
Alkylation
100%
Aminopyridine
50%
Arylation
100%
Chemoselectivity
50%
Chloropyridine
50%
Cyclobutane
50%
Deprotonation
50%
Diastereomer
100%
Dihydroxybenzoate
50%
Diphenylpyraline
50%
Ebastine
50%
Ester Hydrolysis
50%
Etherification
100%
Formylation
50%
Halogen
50%
Lithium
50%
O-alkylation
50%
Phosphotransferase Inhibitor
100%
Protecting Groups
50%
Protective
50%
Quantitative Yield
50%
Reaction Yield
50%