Research Expertise: 
Chemical Biology | Organic Synthesis | Medicinal Chemistry

The goal of my research is to apply synthetic organic chemistry to enhance the understanding of biological processes, especially cellular signaling. Applications of this general research focus include the study of bacterial quorum sensing, a process in which bacteria regulate gene expression, including virulence factors, through the synthesis and detection of small molecule signals and a major research focus of my group. The group’s research in this area has led to the identification of several highly potent and drug-like inhibitors of bacterial virulence in gram-negative bacteria and has illuminated aspects of the biological regulatory circuits involved. We are fully equipped and experienced in chemical synthesis, medicinal chemistry and microbiology.

Member of:
American Chemical Society (ACS)
American Society of Microbiology (ASM)