• 5235 Citations
  • 38 h-Index
1979 …2020

Research output per year

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Research Output

2020

Cross-validation of existing signatures and derivation of a novel 29-gene transcriptomic signature predictive of progression to TB in a Brazilian cohort of household contacts of pulmonary TB

Leong, S., Zhao, Y., Ribeiro-Rodrigues, R., Jones-López, E. C., Acuña-Villaorduña, C., Rodrigues, P. M., Palaci, M., Alland, D., Dietze, R., Ellner, J. J., Johnson, W. E. & Salgame, P., Jan 2020, In : Tuberculosis. 120, 101898.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
2019

Effect of malnutrition on radiographic findings and mycobacterial burden in pulmonary tuberculosis

Hoyt, K. J., Sarkar, S., White, L., Joseph, N. M., Salgame, P., Lakshminarayanan, S., Muthaiah, M., Kumar, S. V., Ellner, J. J., Roy, G., Robert Horsburgh, C. & Hochberg, N. S., Mar 2019, In : PLoS ONE. 14, 3, e0214011.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations

Sarathy, J., Blanc, L., Alvarez-Cabrera, N., O’Brien, P., Dias-Freedman, I., Mina, M., Zimmerman, M., Kaya, F., Liang, H. P. H., Prideaux, B., Dietzold, J., Salgame, P., Savic, R. M., Linderman, J., Kirschner, D. & Pienaar, E., May 2019, In : Antimicrobial agents and chemotherapy. 63, 5, e02516-18.

Rutgers, The State University

Research output: Contribution to journalArticle

6 Scopus citations

Infection resisters: Targets of new research for uncovering natural protective immunity against Mycobacterium tuberculosis

Kaipilyawar, V. & Salgame, P., Jan 1 2019, In : F1000Research. 8, 1698.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Interaction of nutritional status and diabetes on active and latent tuberculosis: A cross-sectional analysis

Kubiak, R. W., Sarkar, S., Horsburgh, C. R., Roy, G., Kratz, M., Reshma, A., Knudsen, S., Salgame, P., Ellner, J. J., Drain, P. K. & Hochberg, N. S., Jul 16 2019, In : BMC infectious diseases. 19, 1, 627.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Moving toward tuberculosis elimination critical issues for research in diagnostics and therapeutics for tuberculosis infection

Keshavjee, S., Amanullah, F., Cattamanchi, A., Chaisson, R., Dobos, K. M., Fox, G. J., Gendelman, H. E., Gordon, R., Hesseling, A., Le Van, H., Kampmann, B., Kana, B., Khuller, G., Lewinsohn, D. M., Lewinsohn, D. A., Lin, P. L., Lu, L. L., Maartens, G., Owen, A., Protopopova, M. & 12 others, Rengarajan, J., Rubin, E., Salgame, P., Schurr, E., Seddon, J. A., Swindells, S., Tobin, D. M., Udwadia, Z., Walzl, G., Srinivasan, S., Rustomjee, R. & Nahid, P., Mar 1 2019, In : American journal of respiratory and critical care medicine. 199, 5, p. 564-571 8 p.

Rutgers, The State University

Research output: Contribution to journalReview article

3 Scopus citations

QuantiFERON®-TB Gold In-Tube reliability for immigrants with parasitic infections in Boston, USA

Epstein, R. L., Bhagavathula, M., Saag, L. A., Verma, S., Kan, C. K., Mesick, J., Kamineni, P., White, L. F., Barnett, E. D., Salgame, P. & Hochberg, N. S., Apr 1 2019, In : International Journal of Tuberculosis and Lung Disease. 23, 4, p. 482-490 9 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Toll-like receptor 2 prevents neutrophil-driven immunopathology during infection with Mycobacterium tuberculosis by curtailing CXCL5 production

Gopalakrishnan, A., Dietzold, J., Verma, S., Bhagavathula, M. & Salgame, P., Mar 1 2019, In : Infection and immunity. 87, 3, e0076018.

Rutgers, The State University

Research output: Contribution to journalArticle

2 Scopus citations

Transmission phenotype of mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology

Verma, S., Bhatt, K., Lovey, A., Ribeiro-Rodrigues, R., Durbin, J., Jones-López, E. C., Palaci, M., Vinhas, S. A., Alland, D., Dietze, R., Ellner, J. J. & Salgame, P., Mar 2019, In : PLoS pathogens. 15, 3, e1007613.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Undernutrition and Tuberculosis: Public Health Implications

Sinha, P., Davis, J., Saag, L., Wanke, C., Salgame, P., Mesick, J., Horsburgh, C. R. & Hochberg, N. S., Jan 1 2019, In : Journal of Infectious Diseases. 219, 9, p. 1356-1363 8 p., jiy675.

Rutgers, The State University

Research output: Contribution to journalReview article

8 Scopus citations
2018

Ambroxol induces autophagy and potentiates rifampin antimycobacterial activity

Choi, S. W., Gu, Y., Peters, R. S., Salgame, P., Ellner, J. J., Timmins, G. S. & Deretica, V., Sep 2018, In : Antimicrobial agents and chemotherapy. 62, 9, e01019-18.

Rutgers, The State University

Research output: Contribution to journalArticle

6 Scopus citations

Existing blood transcriptional classifiers accurately discriminate active tuberculosis from latent infection in individuals from south India

Leong, S., Zhao, Y., Joseph, N. M., Hochberg, N. S., Sarkar, S., Pleskunas, J., Hom, D., Lakshminarayanan, S., Horsburgh, C. R., Roy, G., Ellner, J. J., Johnson, W. E. & Salgame, P., Mar 2018, In : Tuberculosis. 109, p. 41-51 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

7 Scopus citations

Intensity of exposure to pulmonary tuberculosis determines risk of tuberculosis infection and disease

Acuña-Villaorduña, C., Jones-López, E. C., Fregona, G., Marques-Rodrigues, P., Gaeddert, M., Geadas, C., Hadad, D. J., White, L. F., Molina, L. P. D., Vinhas, S., Ribeiro-Rodrigues, R., Salgame, P., Palaci, M., Alland, D., Ellner, J. J. & Dietze, R., Jan 1 2018, In : European Respiratory Journal. 51, 1, 1701578.

Rutgers, The State University

Research output: Contribution to journalArticle

12 Scopus citations

Synergistic lethality of a binary inhibitor of mycobacterium tuberculosis kasA

Kumar, P., Capodagli, G. C., Awasthi, D., Shrestha, R., Maharaja, K., Sukheja, P., Li, S. G., Inoyama, D., Zimmerman, M., Liang, H. P. H., Sarathy, J., Mina, M., Rasic, G., Russo, R., Perryman, A. L., Richmann, T., Gupta, A., Singleton, E., Verma, S., Husain, S. & 11 others, Soteropoulos, P., Wang, Z., Morris, R., Porter, G., Agnihotri, G., Salgame, P., Ekins, S., Rhee, K. Y., Neiditch, M. B., Freundlich, J. S. & Alland, D., Nov 1 2018, In : mBio. 9, 6, e02101-17.

Rutgers, The State University

Research output: Contribution to journalArticle

6 Scopus citations

"Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets"

Verma, S., Du, P., Nakanjako, D., Hermans, S., Briggs, J., Nakiyingi, L., Ellner, J. J., Manabe, Y. C. & Salgame, P., May 15 2018, In : BMC infectious diseases. 18, 1, 220.

Rutgers, The State University

Research output: Contribution to journalArticle

2 Scopus citations
2017

Comorbidities in pulmonary tuberculosis cases in Puducherry and Tamil Nadu, India: Opportunities for intervention

Hochberg, N. S., Sarkar, S., Horsburgh, C. R., Knudsen, S., Pleskunas, J., Sahu, S., Kubiak, R. W., Govindarajan, S., Salgame, P., Lakshminarayanan, S., Sivaprakasam, A., White, L. F., Joseph, N. M., Ellner, J. J. & Roy, G., Aug 2017, In : PLoS ONE. 12, 8, e0183195.

Rutgers, The State University

Research output: Contribution to journalArticle

8 Scopus citations

Divergent Functions of TLR2 on hematopoietic and nonhematopoietic cells during chronic mycobacterium tuberculosis infection

Konowich, J., Gopalakrishnan, A., Dietzold, J., Verma, S., Bhatt, K., Rafi, W. & Salgame, P., Jan 15 2017, In : Journal of Immunology. 198, 2, p. 741-748 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

3 Scopus citations

Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy

Zimmerman, M., Lestner, J., Prideaux, B., O'Brien, P., Dias-Freedman, I., Chen, C., Dietzold, J., Daudelin, I., Kaya, F., Blanc, L., Chen, P. Y., Park, S., Salgame, P. & Sarathy, J., Sep 2017, In : Antimicrobial agents and chemotherapy. 61, 9, e00924-17.

Rutgers, The State University

Research output: Contribution to journalArticle

28 Scopus citations

Incident Mycobacterium tuberculosis infection in household contacts of infectious tuberculosis patients in Brazil

Jones-López, E. C., Acuña-Villaorduña, C., Fregona, G., Marques-Rodrigues, P., White, L. F., Hadad, D. J., Dutra-Molina, L. P., Vinhas, S., McIntosh, A. I., Gaeddert, M., Ribeiro-Rodrigues, R., Salgame, P., Palaci, M., Alland, D., Ellner, J. J. & Dietze, R., Aug 18 2017, In : BMC infectious diseases. 17, 1, 576.

Rutgers, The State University

Research output: Contribution to journalArticle

4 Scopus citations

Strains of Mycobacterium tuberculosis transmitting infection in Brazilian households and those associated with community transmission of tuberculosis

Vinhas, S. A., Jones-López, E. C., Ribeiro Rodrigues, R., Gaeddert, M., Peres, R. L., Marques-Rodrigues, P., de Aguiar, P. P. L., White, L. F., Alland, D., Salgame, P., Hom, D., Ellner, J. J., Dietze, R., Collins, L. F., Shashkina, E., Kreiswirth, B. & Palaci, M., May 1 2017, In : Tuberculosis. 104, p. 79-86 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

3 Scopus citations
2016

1,25 (OH)2D3 treatment alters the granulomatous response in M. tuberculosis infected mice

Bhatt, K., Rafi, W., Shah, N., Christakos, S. & Salgame, P., Oct 4 2016, In : Scientific reports. 6, 34469.

Rutgers, The State University

Research output: Contribution to journalArticle

3 Scopus citations
25 Scopus citations

Vaccine-mediated immunity to experimental Mycobacterium tuberculosis is not impaired in the absence of Toll-like receptor 9

Gopalakrishnan, A., Dietzold, J. & Salgame, P., Apr 1 2016, In : Cellular Immunology. 302, p. 11-18 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

3 Scopus citations
2015

Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice

Goodsmith, N., Guo, X. V., Vandal, O. H., Vaubourgeix, J., Wang, R., Botella, H., Song, S., Bhatt, K., Liba, A., Salgame, P., Schnappinger, D. & Ehrt, S., Jan 1 2015, In : PLoS pathogens. 11, 2, e1004645.

Rutgers, The State University

Research output: Contribution to journalArticle

14 Scopus citations

Duality of lipid mediators in host response against Mycobacterium tuberculosis: Good cop, bad cop

Dietzold, J., Gopalakrishnan, A. & Salgame, P., Mar 3 2015, In : F1000Prime Reports. 7, 29.

Rutgers, The State University

Research output: Contribution to journalArticle

11 Scopus citations

Latent tuberculosis infection - Revisiting and revising concepts

Salgame, P., Geadas, C., Collins, L., Jones-López, E. & Ellner, J. J., Jul 1 2015, In : Tuberculosis. 95, 4, p. 373-384 12 p., 1324.

Rutgers, The State University

Research output: Contribution to journalReview article

61 Scopus citations
12 Scopus citations

Quest for correlates of protection against tuberculosis

Bhatt, K., Verma, S., Ellner, J. J. & Salgame, P., Mar 1 2015, In : Clinical and Vaccine Immunology. 22, 3, p. 258-266 9 p.

Rutgers, The State University

Research output: Contribution to journalReview article

67 Scopus citations
2014

Discordance of tuberculin skin test and interferon gamma release assay in recently exposed household contacts of pulmonary TB cases in Brazil

Ribeiro-Rodrigues, R., Kim, S., Coelho Da Silva, F. D., Uzelac, A., Collins, L., Palaci, M., Alland, D., Dietze, R., Ellner, J. J., Jones-López, E. & Salgame, P., May 12 2014, In : PLoS ONE. 9, 5, e96564.

Rutgers, The State University

Research output: Contribution to journalArticle

19 Scopus citations

Importance of cough and M. tuberculosis strain type as risks for increased transmission within households

Jones-López, E. C., Kim, S., Fregona, G., Marques-Rodrigues, P., Hadad, D. J., Molina, L. P. D., Vinhas, S., Reilly, N., Moine, S., Chakravorty, S., Gaeddert, M., Ribeiro-Rodrigues, R., Salgame, P., Palaci, M., Alland, D., Ellner, J. J. & Dietze, R., Jul 2 2014, In : PLoS ONE. 9, 7, e100984.

Rutgers, The State University

Research output: Contribution to journalArticle

25 Scopus citations
2013

Effect of helminth-induced immunity on infections with microbial pathogens

Salgame, P., Yap, G. & Gause, W., Nov 4 2013, In : Nature Immunology. 14, 11, p. 1118-1126 9 p.

Rutgers, The State University

Research output: Contribution to journalReview article

144 Scopus citations

Equivalent functions for B7.1 and B7.2 costimulation in mediating host resistance to Mycobacterium tuberculosis

Bhatt, K., Kim, A., Kim, A., Mathur, S. & Salgame, P., Sep 1 2013, In : Cellular Immunology. 285, 1-2, p. 69-75 7 p.

Rutgers, The State University

Research output: Contribution to journalArticle

11 Scopus citations
35 Scopus citations
2012

'Coinfection-helminthes and tuberculosis'

Rafi, W., Ribeiro-Rodrigues, R., Ellner, J. J. & Salgame, P., May 1 2012, In : Current opinion in HIV and AIDS. 7, 3, p. 239-244 6 p.

Rutgers, The State University

Research output: Contribution to journalReview article

43 Scopus citations

Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1

Qualls, J. E., Subramanian, C., Rafi, W., Smith, A. M., Balouzian, L., Defreitas, A. A., Shirey, K. A., Reutterer, B., Kernbauer, E., Stockinger, S., Decker, T., Miyairi, I., Vogel, S. N., Salgame, P., Rock, C. O. & Murray, P. J., Sep 13 2012, In : Cell Host and Microbe. 12, 3, p. 313-323 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

72 Scopus citations
2011

Development of a secondary immune response to Mycobacterium tuberculosis is independent of toll-like receptor 2

McBride, A., Bhatt, K. & Salgame, P., Mar 1 2011, In : Infection and immunity. 79, 3, p. 1118-1123 6 p.

Rutgers, The State University

Research output: Contribution to journalArticle

16 Scopus citations

Erratum: Imatinib-sensitive tyrosine kinases regulate mycobacterial pathogenesis and represent therapeutic targets against tuberculosis (Cell Host and Microbe)

Napier, R. J., Rafi, W., Cheruvu, M., Powell, K. R., Zaunbrecher, M. A., Bornmann, W., Salgame, P., Shinnick, T. M. & Kalman, D., Dec 15 2011, In : Cell Host and Microbe. 10, 6, 1 p.

Research output: Contribution to journalComment/debate

Human breast tumor cells express IL-10 and IL-12p40 transcripts and proteins, but do not produce IL-12p70

Heckel, M. C., Wolfson, A., Slachta, C. A., Schwarting, R., Salgame, P., Katsetos, C. D. & Platsoucas, C. D., Jan 1 2011, In : Cellular Immunology. 266, 2, p. 143-153 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

26 Scopus citations

Imatinib-Sensitive tyrosine kinases regulate mycobacterial pathogenesis and represent therapeutic targets against tuberculosis

Napier, R. J., Rafi, W., Cheruvu, M., Powell, K. R., Zaunbrecher, M. A., Bornmann, W., Salgame, P., Shinnick, T. M. & Kalman, D., Nov 17 2011, In : Cell Host and Microbe. 10, 5, p. 475-485 11 p.

Rutgers, The State University

Research output: Contribution to journalArticle

105 Scopus citations

MMPs in tuberculosis: Granuloma creators and tissue destroyers

Salgame, P., May 2 2011, In : Journal of Clinical Investigation. 121, 5, p. 1686-1688 3 p.

Rutgers, The State University

Research output: Contribution to journalComment/debate

39 Scopus citations

Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway

Potian, J. A., Rafi, W., Bhatt, K., McBride, A., Gause, W. & Salgame, P., Aug 29 2011, In : Journal of Experimental Medicine. 208, 9, p. 1863-1874 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

114 Scopus citations
2010

Regulation of type 1 diabetes, tuberculosis, and asthma by parasites

Liu, Z., Liu, Q., Bleich, D., Salgame, P. & Gause, W., Jan 1 2010, In : Journal of Molecular Medicine. 88, 1, p. 27-38 12 p.

Rutgers, The State University

Research output: Contribution to journalReview article

16 Scopus citations
2009

B7 costimulation is critical for host control of chronic Mycobacterium tuberculosis infection

Bhatt, K., Uzelac, A., Mathur, S., McBride, A., Potian, J. & Salgame, P., Mar 15 2009, In : Journal of Immunology. 182, 6, p. 3793-3800 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

20 Scopus citations

The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates

Colangeli, R., Haq, A., Arcus, V. L., Summers, E., Magliozzo, R. S., McBride, A., Mitra, A. K., Radjainia, M., Khajo, A., Jacobs, W. R., Salgame, P. & Alland, D., Mar 17 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 11, p. 4414-4418 5 p.

Rutgers, The State University

Research output: Contribution to journalArticle

69 Scopus citations
2008

Comparative evaluation of cytokines, T-cell apoptosis, and costimulatory molecule expression in tuberculous and nontuberculous pleurisy

Rajavelu, P., Pokkali, S., Umashankar, P. M. B. B. S., Bhatt, K., Narayanan, P. R., Salgame, P. & Das, S. D., Dec 1 2008, In : Clinical and translational science. 1, 3, p. 209-214 6 p.

Rutgers, The State University

Research output: Contribution to journalArticle

2 Scopus citations
21 Scopus citations
3 Scopus citations
2007

Disparity in IL-12 release in dendritic cells and macrophages in response to Mycobacterium tuberculosis is due to use of distinct TLRs

Pompei, L., Jang, S., Zamlynny, B., Ravikumar, S., McBride, A., Hickman, S. P. & Salgame, P., Apr 15 2007, In : Journal of Immunology. 178, 8, p. 5192-5199 8 p.

Rutgers, The State University

Research output: Contribution to journalArticle

71 Scopus citations

Host innate immune response to Mycobacterium tuberculosis

Bhatt, K. & Salgame, P., Jul 1 2007, In : Journal of Clinical Immunology. 27, 4, p. 347-362 16 p.

Rutgers, The State University

Research output: Contribution to journalReview article

144 Scopus citations