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Dive into the research topics where Peter Melera is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence
Obajimi, O., Keen, J. C. & Melera, P. W., Aug 1 2009, In: Prostate. 69, 11, p. 1206-1221 16 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
The depletion of cellular ATP by AG2034 mediates cell death or cytostasis in a hypoxanthine-dependent manner in human prostate cancer cells
Obajimi, O. & Melera, P. W., Jul 2008, In: Cancer chemotherapy and pharmacology. 62, 2, p. 215-226 12 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folate repletion, confer drug resistance to CHL cells
Zhu, W. Y., Bunni, M., Priest, D. G., DiCapua, J. L., Dressler, J. M., Chen, Z. & Melera, P. W., Sep 2002, In: Journal of Experimental Therapeutics and Oncology. 2, 5, p. 264-277 14 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Basal levels of metallothionein I and II expression in mouse embryo fibroblasts enhance growth in low folate through a cell cycle mediated pathway
Zhu, W. Y. & Melera, P. W., 2001, In: Cell Biology International. 25, 12, p. 1261-1269 9 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Further characterization of the sixth transmembrane domain of Pgp1 by site-directed mutagenesis
Song, J. & Melera, P. W., 2001, In: Cancer chemotherapy and pharmacology. 48, 5, p. 339-346 8 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations