• 18443 Citations
  • 73 h-Index
1972 …2020

Research output per year

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Research Output

2019

Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response

Pribis, J. P., García-Villada, L., Zhai, Y., Lewin-Epstein, O., Wang, A. Z., Liu, J., Xia, J., Mei, Q., Fitzgerald, D. M., Bos, J., Austin, R. H., Herman, C., Bates, D., Hadany, L., Hastings, P. J. & Rosenberg, S. M., May 16 2019, In : Molecular cell. 74, 4, p. 785-800.e7

Princeton University

Research output: Contribution to journalArticle

21 Scopus citations
1 Scopus citations

Polyploid giant cancer cells: Unrecognized actuators of tumorigenesis, metastasis, and resistance

Amend, S. R., Torga, G., Lin, K. C., Kostecka, L. G., de Marzo, A., Austin, R. H. & Pienta, K. J., 2019, In : Prostate. 79, 13, p. 1489-1497 9 p.

Princeton University

Research output: Contribution to journalReview article

12 Scopus citations

The role of heterogeneous environment and docetaxel gradient in the emergence of polyploid, mesenchymal and resistant prostate cancer cells

Lin, K. C., Torga, G., Sun, Y., Axelrod, R., Pienta, K. J., Sturm, J. C. & Austin, R. H., Apr 15 2019, In : Clinical and Experimental Metastasis. 36, 2, p. 97-108 12 p.

Princeton University

Research output: Contribution to journalArticle

13 Scopus citations
2018

A bacterial antibiotic resistance accelerator and applications

Bos, J. & Austin, R. H., Jan 1 2018, Methods in Cell Biology. Piel, M., Fletcher, D. & Doh, J. (eds.). Academic Press Inc., p. 41-57 17 p. (Methods in Cell Biology; vol. 147).

Princeton University

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
8 Scopus citations

Emergence of Escherichia coli critically buckled motile helices under stress

Phan, T. V., Morris, R. J., Lam, H. T., Hulamm, P., Black, M. E., Bos, J. & Austin, R. H., Dec 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. 12979-12984 6 p.

Princeton University

Research output: Contribution to journalArticle

2 Scopus citations
2017

Broken flow symmetry explains the dynamics of small particles in deterministic lateral displacement arrays

Kim, S. C., Wunsch, B. H., Hu, H., Smith, J. T., Austin, R. H. & Stolovitzky, G., Jun 27 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 26, p. E5034-E5041

Princeton University

Research output: Contribution to journalArticle

29 Scopus citations

Cancer biology still needs physicists

Austin, R., Oct 24 2017, In : Nature. 550, 7677, 1 p.

Princeton University

Research output: Contribution to journalComment/debate

3 Scopus citations
4 Scopus citations
2016

Automated leukocyte processing by microfluidic deterministic lateral displacement

Civin, C. I., Ward, T., Skelley, A. M., Gandhi, K., Peilun Lee, Z., Dosier, C. R., D'Silva, J. L., Chen, Y., Kim, M. J., Moynihan, J., Chen, X., Aurich, L., Gulnik, S., Brittain, G. C., Recktenwald, D. J., Austin, R. H. & Sturm, J. C., Dec 1 2016, In : Cytometry Part A. 89, 12, p. 1073-1083 11 p.

Princeton University

Research output: Contribution to journalArticle

14 Scopus citations

How to connect time-lapse recorded trajectories of motile microorganisms with dynamical models in continuous time

Pedersen, J. N., Li, L., Grǎdinaru, C., Austin, R. H., Cox, E. C. & Flyvbjerg, H., Dec 6 2016, In : Physical Review E. 94, 6, 062401.

Princeton University

Research output: Contribution to journalArticle

14 Scopus citations

Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20nm

Wunsch, B. H., Smith, J. T., Gifford, S. M., Wang, C., Brink, M., Bruce, R. L., Austin, R. H., Stolovitzky, G. & Astier, Y., Nov 1 2016, In : Nature Nanotechnology. 11, 11, p. 936-940 5 p.

Princeton University

Research output: Contribution to journalArticle

164 Scopus citations

Oriented collagen fibers direct tumor cell intravasation

Han, W., Chen, S., Yuan, W., Fan, Q., Tian, J., Wang, X., Chen, L., Zhang, X., Wei, W., Liu, R., Qu, J., Jiao, Y., Austin, R. H. & Liu, L., Oct 4 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 40, p. 11208-11213 6 p.

Princeton University

Research output: Contribution to journalArticle

86 Scopus citations

Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecology

Han, J., Jun, Y., Kim, S. H., Hoang, H. H., Jung, Y., Kim, S., Kim, J., Austin, R. H., Lee, S. & Park, S., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. 14283-14288 6 p.

Princeton University

Research output: Contribution to journalArticle

31 Scopus citations
2015

Ancient hot and cold genes and chemotherapy resistance emergence

Wu, A., Zhang, Q., Lambert, G., Khin, Z., Gatenby, R. A., Kim, H. J., Pourmand, N., Bussey, K., Davies, P. C. W., Sturm, J. C. & Austin, R. H., Aug 18 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 33, p. 10467-10472 6 p.

Princeton University

Research output: Contribution to journalArticle

21 Scopus citations

Concentrating genomic length DNA in a microfabricated array

Chen, Y., Abrams, E. S., Boles, T. C., Pedersen, J. N., Flyvbjerg, H., Austin, R. H. & Sturm, J. C., May 15 2015, In : Physical review letters. 114, 19, 198303.

Princeton University

Research output: Contribution to journalArticle

19 Scopus citations

Emergence of antibiotic resistance from multinucleated bacterial filaments

Bos, J., Zhang, Q., Vyawahare, S., Rogers, E., Rosenberg, S. M. & Austin, R. H., Jan 6 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 1, p. 178-183 6 p.

Princeton University

Research output: Contribution to journalArticle

67 Scopus citations

Evolutionary game theory in cancer: First steps in prediction of metastatic cancer progression?

Wu, A., Liao, D. & Austin, R. H., Mar 1 2015, In : Future Oncology. 11, 6, p. 881-883 3 p.

Princeton University

Research output: Contribution to journalArticle

3 Scopus citations

Hidden harmonic quantum states in proteins: Did Davydov get the sign wrong?

Xie, A., Redlich, B., Meer, L. V. D., Vyawahare, S. & Austin, R. H., Oct 7 2015, In : Physica Scripta. 2015, T165, 014042.

Princeton University

Research output: Contribution to journalConference article

22 Scopus citations
7 Scopus citations

Upconverting nanoparticle-based multi-functional nanoplatform for enhanced photodynamic therapy: Promises and perils

Lim, S. F. & Austin, R. H., Feb 3 2015, Applications of Nanoscience in Photomedicine. Elsevier Inc., p. 377-391 15 p.

Princeton University

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Bacteria and game theory: The rise and fall of cooperation in spatially heterogeneous environments

Lambert, G., Vyawahare, S. & Austin, R. H., Aug 6 2014, In : Interface Focus. 4, 4

Princeton University

Research output: Contribution to journalReview article

19 Scopus citations

Beyond evolution: Game theory and the progression of cancer

Austin, R., Aug 6 2014, In : Interface Focus. 4, 4, 20140044.

Princeton University

Research output: Contribution to journalEditorial

Game theory in the death galaxy: Interaction of cancer and stromal cells in tumour microenvironment

Wu, A., Liao, D., Tlsty, T. D., Sturm, J. C. & Austin, R. H., Aug 6 2014, In : Interface Focus. 4, 4, 20140028.

Princeton University

Research output: Contribution to journalArticle

14 Scopus citations

In vitro microbial culture models and their application in drug development

Vyawahare, S., Zhang, Q., Lau, A. & Austin, R. H., Jan 1 2014, In : Advanced Drug Delivery Reviews. 69-70, p. 217-224 8 p.

Princeton University

Research output: Contribution to journalReview article

4 Scopus citations

Physics of biofilms: The initial stages of biofilm formation and dynamics

Lambert, G., Bergman, A., Zhang, Q., Bortz, D. & Austin, R., Apr 2014, In : New Journal of Physics. 16, 045005.

Princeton University

Research output: Contribution to journalArticle

11 Scopus citations

Ratchets in hydrodynamic flow: More than waterwheels

Sturm, J. C., Cox, E. C., Comella, B. & Austin, R. H., Dec 6 2014, In : Interface Focus. 4, 6, 20140054.

Princeton University

Research output: Contribution to journalReview article

8 Scopus citations

Rejoice in the hubris: Useful things biologists could do for physicists

Austin, R. H., Oct 1 2014, In : Physical biology. 11, 5, 053015.

Princeton University

Research output: Contribution to journalReview article

2 Scopus citations

Resistance to chemotherapy: Patient variability and cellular heterogeneity

Kessler, D. A., Austin, R. H. & Levine, H., Sep 1 2014, In : Cancer Research. 74, 17, p. 4663-4670 8 p.

Princeton University

Research output: Contribution to journalArticle

27 Scopus citations
2013

A physical sciences network characterization of non-tumorigenic and metastatic cells

Agus, D. B., Alexander, J. F., Arap, W., Ashili, S., Aslan, J. E., Austin, R. H., Backman, V., Bethel, K. J., Bonneau, R., Chen, W. C., Chen-Tanyolac, C., Choi, N. C., Curley, S. A., Dallas, M., Damania, D., Davies, P. C. W., Decuzzi, P., Dickinson, L., Estevez-Salmeron, L., Estrella, V. & 75 others, Ferrari, M., Fischbach, C., Foo, J., Fraley, S. I., Frantz, C., Fuhrmann, A., Gascard, P., Gatenby, R. A., Geng, Y., Gerecht, S., Gillies, R. J., Godin, B., Grady, W. M., Greenfield, A., Hemphill, C., Hempstead, B. L., Hielscher, A., Hillis, W. D., Holland, E. C., Ibrahim-Hashim, A., Jacks, T., Johnson, R. H., Joo, A., Katz, J. E., Kelbauskas, L., Kesselman, C., King, M. R., Konstantopoulos, K., Kraning-Rush, C. M., Kuhn, P., Kung, K., Kwee, B., Lakins, J. N., Lambert, G., Liao, D., Licht, J. D., Liphardt, J. T., Liu, L., Lloyd, M. C., Lyubimova, A., Mallick, P., Marko, J., McCarty, O. J. T., Meldrum, D. R., Michor, F., Mumenthaler, S. M., Nandakumar, V., O'Halloran, T. V., Oh, S., Pasqualini, R., Paszek, M. J., Philips, K. G., Poultney, C. S., Rana, K., Reinhart-King, C. A., Ros, R., Semenza, G. L., Senechal, P., Shuler, M. L., Srinivasan, S., Staunton, J. R., Stypula, Y., Subramanian, H., Tlsty, T. D., Tormoen, G. W., Tseng, Y., Van Oudenaarden, A., Verbridge, S. S., Wan, J. C., Weaver, V. M., Widom, J., Will, C., Wirtz, D., Wojtkowiak, J. & Wu, P. H., 2013, In : Scientific reports. 3, 1449.

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

93 Scopus citations

Cell motility and drug gradients in the emergence of resistance to chemotherapy

Wu, A., Loutherback, K., Lambert, G., Estéèez-Salmerón, L., Tlsty, T. D., Austin, R. H. & Sturm, J. C., Oct 1 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. 16103-16108 6 p.

Princeton University

Research output: Contribution to journalArticle

53 Scopus citations

Minimization of thermodynamic costs in cancer cell invasion

Liu, L., Duclos, G., Sun, B., Lee, J., Wu, A., Kam, Y., Sontag, E. D., Stone, H. A., Sturm, J. C., Gatenby, R. A. & Austin, R. H., Jan 29 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 5, p. 1686-1691 6 p.

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

44 Scopus citations
2012

Applications of Microfluidics in Stem Cell Biology

Zhang, Q. & Austin, R. H., Nov 2012, In : BioNanoScience. 2, 4, p. 277-286 10 p.

Princeton University

Research output: Contribution to journalArticle

35 Scopus citations

Deterministic separation of cancer cells from blood at 10 mL/min

Loutherback, K., D'Silva, J., Liu, L., Wu, A., Austin, R. H. & Sturm, J. C., 2012, In : AIP Advances. 2, 4, 042107.

Princeton University

Research output: Contribution to journalArticle

146 Scopus citations

DNA confinement in nanochannels: Physics and biological applications

Reisner, W., Pedersen, J. N. & Austin, R. H., Oct 1 2012, In : Reports on Progress in Physics. 75, 10, 106601.

Princeton University

Research output: Contribution to journalArticle

217 Scopus citations

Free energies, landscapes, and fitness in evolution dynamics

Austin, R. H., Jan 1 2012, Quantitative Biology: From Molecular to Cellular Systems. CRC Press, p. 1-21 21 p.

Princeton University

Research output: Chapter in Book/Report/Conference proceedingChapter

Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensing

Bougot-Robin, K., Li, S., Zhang, Y., Kodzius, R., Hsing, I. M., Benisty, H., Austin, R. H. & Wen, W., Jan 1 2012, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, p. 1324-1326 3 p. (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).

Princeton University

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Physics of cancer: The impact of heterogeneity

Zhang, Q. & Austin, R. H., Feb 27 2012, In : Annual Review of Condensed Matter Physics. 3, 1, p. 363-382 20 p.

Princeton University

Research output: Contribution to journalReview article

20 Scopus citations

Physics of cancer propagation: A game theory perspective

Cleveland, C., Liao, D. & Austin, R., 2012, In : AIP Advances. 2, 1, 011202.

Princeton University

Research output: Contribution to journalArticle

10 Scopus citations

Preface: Physics of cancer

Austin, R. H. & Gerstman, B. S., 2012, In : AIP Advances. 2, 1, 010901.

Princeton University

Research output: Contribution to journalEditorial

1 Scopus citations
2011

Acceleration of emergence of bacterial antibiotic resistance in connected microenvironments

Zhang, Q., Lambert, G., Liao, D., Kim, H., Robin, K., Tung, C. K., Pourmand, N. & Austin, R. H., Oct 23 2011, In : Science. 333, 6050, p. 1764-1767 4 p.

Princeton University

Research output: Contribution to journalArticle

289 Scopus citations

Acceleration of the emergence of bacterial antibiotic resistance

Zhang, Q., Liao, D. & Austin, R. H., Dec 1 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. p. 1481-1483 3 p. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; vol. 3).

Princeton University

Research output: Chapter in Book/Report/Conference proceedingConference contribution

An analogy between the evolution of drug resistance in bacterial communities and malignant tissues

Lambert, G., Estévez-Salmeron, L., Oh, S., Liao, D., Emerson, B. M., Tlsty, T. D. & Austin, R. H., May 2011, In : Nature Reviews Cancer. 11, 5, p. 375-382 8 p.

Princeton University

Research output: Contribution to journalReview article

107 Scopus citations

Anomalous spatial redistribution of competing bacteria under starvation conditions

Lambert, G., Liao, D., Vyawahare, S. & Austin, R. H., Apr 2011, In : Journal of bacteriology. 193, 8, p. 1878-1883 6 p.

Princeton University

Research output: Contribution to journalArticle

14 Scopus citations

Collapse of DNA in ac electric fields

Zhou, C., Reisner, W. W., Staunton, R. J., Ashan, A., Austin, R. H. & Riehn, R., Jun 16 2011, In : Physical review letters. 106, 24, 248103.

Princeton University

Research output: Contribution to journalArticle

24 Scopus citations