Projects per year
Personal profile
Research interests
We use human induced pluripotent stem cells (iPSC) to model neurons with specific genetic variants to study Schizophrenia, Bipolar, and addiction disorders.
Education/Academic qualification
Cellular and Molecular Biology, Ph.D., Structure and expression of a 5S ribosomal RNA gene from the Syrian hamster genome, University of Michigan
Sep 1 1977 → Aug 20 1981
Award Date: Aug 20 1981
Biology, B.S., University of Connecticut
Sep 1 1973 → May 23 1977
Award Date: May 23 1977
Molecular Biology, Postdoctoral Training, Sequences required for poly(A) processing of mRNAs, Rockefeller University
Sep 1 1982 → Aug 31 1985
Molecular Biology, Postdoctoral Training, Ribosomal RNA gene expression, University of Michigan
Sep 1 1981 → Aug 31 1982
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Cellular consequences and convergent biology of schizophrenia-associated rare variants in the diverse GPC cohort
Mulle, J., Pato, C., Hart, R. & Pang, Z. Z. P.
National Institute of Mental Health
8/1/22 → 5/31/24
Project: Research project
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High throughput multicompartment culture chambers to develop neurocircuit models of addiction risk
National Institute on Drug Abuse
4/1/15 → 3/31/16
Project: Research project
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Developing an In Vitro Neurocircuitry Model of Addiction using Risk-Associated Hu
Pang, Z. P., Hart, R. & Pang, Z.
National Institute on Drug Abuse
4/1/13 → 3/31/16
Project: Research project
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Phenotypic analysis of human iPSC carrying addiction-associated gene variants
National Institute on Drug Abuse
9/15/11 → 6/30/14
Project: Research project
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5. Collaborative Study on the Genetics of Alcoholism: Functional genomics
COGA Collaborators, Aug 2 2023, (E-pub ahead of print) In: Genes, Brain and Behavior. p. e12855Research output: Contribution to journal › Review article › peer-review
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Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons
Popova, D., Gameiro-Ros, I., Youssef, M. M., Zalamea, P., Morris, A. D., Prytkova, I., Jadali, A., Kwan, K. Y., Kamarajan, C., Salvatore, J. E., Xuei, X., Chorlian, D. B., Porjesz, B., Kuperman, S., Dick, D. M., Goate, A., Edenberg, H. J., Tischfield, J. A., Pang, Z. P., Slesinger, P. A., & 1 others, Feb 2023, In: Molecular psychiatry. 28, 2, p. 746-758 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex
Salamon, I., Park, Y., Miškić, T., Kopić, J., Matteson, P., Page, N. F., Roque, A., McAuliffe, G. W., Favate, J., Garcia-Forn, M., Shah, P., Judaš, M., Millonig, J. H., Kostović, I., De Rubeis, S., Hart, R., Krsnik, Ž. & Rasin, M. R., Dec 2023, In: Nature communications. 14, 1, 6025.Research output: Contribution to journal › Article › peer-review
Open Access -
Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in The Collaborative Study on the Genetics of Alcoholism
The Collaborative Study on the Genetics of Alcoholism (COGA), May 2023, In: Alcohol: Clinical and Experimental Research. 47, 5, p. 919-929 11 p.Research output: Contribution to journal › Article › peer-review
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Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons
Sun, J. K. L., Wu, D., Wong, G. C. N., Lau, T. M., Yang, M., Hart, R. P., Kwan, K. M., Chan, H. Y. E. & Chow, H. M., Feb 2023, In: Aging cell. 22, 2, e13772.Research output: Contribution to journal › Article › peer-review
Open Access