Subash Jonnalagadda

    • 540 Citations
    • 13 h-Index
    20022020
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    Personal profile

    Research interests

    Research Expertise: 
    Organic & Medicinal Chemistry | Organoboron Chemistry | Alternate Energy Materials

    Medicinal Chemistry: We have been developing novel aza- and bora-heterocyclic compounds and betulin-based natural product derivatives as anti-cancer agents. In collaboration with Rowan School of Osteopathic Medicine, we have also identified few Withaferin-serotonin conjugates as potential therapeutic options for the treatment of Alzheimers’ Disease.

    Value Added Chemicals from Biomass: Recent efforts in this area have included the development of new protocols for the effective conversion of biomass derived cellulosic materials into chemicals such as hydroxymethyl furfural and furan dicarboxylic acid for applications as bio-based polymers.

    Honors and Awards:
    Rowan University Wall of Fame Teaching Award, 2013, 2016
    Eli Lilly International Graduate Scholar, 2000-2005, Purdue University

    Member of:
    American Chemical Society (www.acs.org)

    Education/Academic qualification

    Pondicherry University

    University of Hyderabad

    Fingerprint Dive into the research topics where Subash Jonnalagadda is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 2 Similar Profiles
    Alkylation Chemical Compounds
    Cytotoxicity Chemical Compounds
    Pyrrolidonecarboxylic Acid Chemical Compounds
    Cells Chemical Compounds
    Lactams Chemical Compounds
    Aldehydes Chemical Compounds
    Derivatives Chemical Compounds
    Cycloaddition Chemical Compounds

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 2010 2020

    Research Output 2002 2019

    • 540 Citations
    • 13 h-Index
    • 26 Article
    • 6 Chapter
    • 1 Comment/debate
    • 1 Review article

    Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ß activity

    Fultang, N., Illendula, A., Chen, B., Wu, C., Jonnalagadda, S., Baird, N., Klase, Z. & Peethambaran, B., May 1 2019, In : PLoS ONE. 14, 5, e0217789.

    Rowan University

    Research output: Contribution to journalArticle

    Open Access
    Triple Negative Breast Neoplasms
    phosphatidylinositol 3-kinase
    Phosphatidylinositol 3-Kinases
    breast neoplasms
    Modulation
    3 Citations (Scopus)

    Benzoboroxoles: Synthesis and applications in medicinal chemistry

    Mereddy, G. R., Chakradhar, A., Rutkoski, R. M. & Jonnalagadda, S., Jun 15 2018, In : Journal of Organometallic Chemistry. 865, p. 12-22 11 p.

    Rowan University

    Research output: Contribution to journalArticle

    Pharmaceutical Chemistry
    chemistry
    synthesis
    Organic Chemistry
    Boronic Acids

    Novel methodologies for the synthesis of biologically active Boron-based small molecules

    Jonnalagadda, S., Penczuk, B. J., Twomey, K. M., Fishbein, S. H. & Suman, P., Aug 7 2018, Boron in Medicine. World Scientific Publishing Co. Pte Ltd, Vol. 4-4. p. 15-48 34 p.

    Rowan University

    Research output: Chapter in Book/Report/Conference proceedingChapter

    9 Citations (Scopus)
    Molecular dynamics
    DNA
    Ligands
    simulation
    Intercalation
    10 Citations (Scopus)

    Recent Developments on the Synthesis and Applications of Betulin and Betulinic Acid Derivatives as Therapeutic Agents

    Jonnalagadda, S., Suman, P., Morgan, D. C. & Seay, J. N., Jan 1 2017, Studies in Natural Products Chemistry. Elsevier B.V., p. 45-84 40 p. (Studies in Natural Products Chemistry; vol. 53).

    Rowan University

    Research output: Chapter in Book/Report/Conference proceedingChapter

    betulin
    chemical derivatives
    therapeutics
    synthesis
    Betula