• 1594 Citations
  • 17 h-Index
20042020

Research output per year

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Research Output

  • 1594 Citations
  • 17 h-Index
  • 33 Article
  • 4 Review article
  • 1 Chapter
  • 1 Comment/debate
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Article
2020
Open Access

G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer

Dragan, M., Nguyen, M. U., Guzman, S., Goertzen, C., Brackstone, M., Dhillo, W. S., Bech, P. R., Clarke, S., Abbara, A., Tuck, A. B., Hess, D. A., Pine, S. R., Zong, W. X., Wondisford, F. E., Su, X., Babwah, A. V. & Bhattacharya, M., Feb 1 2020, In : Cell Death and Disease. 11, 2, 106.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access

HNF4 Regulates Fatty Acid Oxidation and Is Required for Renewal of Intestinal Stem Cells in Mice

Chen, L., Vasoya, R. P., Toke, N. H., Parthasarathy, A., Luo, S., Chiles, E., Flores, J., Gao, N., Bonder, E. M., Su, X. & Verzi, M. P., Mar 2020, In : Gastroenterology. 158, 4, p. 985-999.e9

Rutgers, The State University

Research output: Contribution to journalArticle

1 Scopus citations

Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression

Liu, J., Zhang, C., Wu, H., Sun, X. X., Li, Y., Huang, S., Yue, X., Lu, S. E., Shen, Z., Su, X., White, E., Haffty, B. G., Hu, W. & Feng, Z., Jun 1 2020, In : Journal of Clinical Investigation. 130, 6, p. 3253-3269 17 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access

Serine Catabolism Feeds NADH when Respiration Is Impaired

Yang, L., Garcia Canaveras, J. C., Chen, Z., Wang, L., Liang, L., Jang, C., Mayr, J. A., Zhang, Z., Ghergurovich, J. M., Zhan, L., Joshi, S., Hu, Z., McReynolds, M. R., Su, X., White, E., Morscher, R. J. & Rabinowitz, J. D., Apr 7 2020, In : Cell Metabolism. 31, 4, p. 809-821.e6

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

2 Scopus citations
2019

Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient kras-driven lung tumorigenesis

Bhatt, V., Khayati, K., Hu, Z. S., Lee, A., Kamran, W., Su, X. & Guo, J. Y., Feb 1 2019, In : Genes and Development. 33, 3-4, p. 150-165 16 p.

Rutgers, The State University

Research output: Contribution to journalArticle

8 Scopus citations

ElemCor: Accurate data analysis and enrichment calculation for high-resolution LC-MS stable isotope labeling experiments

Du, D., Tan, L., Wang, Y., Peng, B., Weinstein, J. N., Wondisford, F. E., Su, X. & Lorenzi, P. L., Feb 19 2019, In : BMC bioinformatics. 20, 1, 89.

Rutgers, The State University

Research output: Contribution to journalArticle

5 Scopus citations

Fast LC-MS quantitation of glucose and glycerol via enzymatic derivatization

Chiles, E., Wang, Y., Kalemba, K. M., Kwon, H., Wondisford, F. E. & Su, X., Jun 15 2019, In : Analytical Biochemistry. 575, p. 40-43 4 p.

Rutgers, The State University

Research output: Contribution to journalArticle

3 Scopus citations

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism

Bott, A. J., Shen, J., Tonelli, C., Zhan, L., Sivaram, N., Jiang, Y. P., Yu, X., Bhatt, V., Chiles, E., Zhong, H., Maimouni, S., Dai, W., Velasquez, S., Pan, J. A., Muthalagu, N., Morton, J., Anthony, T. G., Feng, H., Lamers, W. H., Murphy, D. J. & 9 others, Guo, J. Y., Jin, J., Crawford, H. C., Zhang, L., White, E., Lin, R. Z., Su, X., Tuveson, D. A. & Zong, W. X., Oct 29 2019, In : Cell Reports. 29, 5, p. 1287-1298.e6

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Glycerol induces G6pc in primary mouse hepatocytes and is the preferred substrate for gluconeogenesis both in vitro and in vivo

Kalemba, K. M., Wang, Y., Xu, H., Chiles, E., McMillin, S. M., Kwon, H., Su, X. & Wondisford, F. E., Nov 29 2019, In : Journal of Biological Chemistry. 294, 48, p. 18017-18028 12 p.

Rutgers, The State University

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Peak Annotation and Verification Engine for Untargeted LC-MS Metabolomics

Wang, L., Xing, X., Chen, L., Yang, L., Su, X., Rabitz, H., Lu, W. & Rabinowitz, J. D., Feb 5 2019, In : Analytical Chemistry. 91, 3, p. 1838-1846 9 p.

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

8 Scopus citations

The asymmetric function of Dph1–Dph2 heterodimer in diphthamide biosynthesis

Dong, M., Dando, E. E., Kotliar, I., Su, X., Dzikovski, B., Freed, J. H. & Lin, H., Sep 1 2019, In : Journal of Biological Inorganic Chemistry. 24, 6, p. 777-782 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Autophagy maintains tumour growth through circulating arginine

Poillet-Perez, L., Xie, X., Zhan, L., Yang, Y., Sharp, D. W., Hu, Z. S., Su, X., Maganti, A., Jiang, C., Lu, W., Zheng, H., Bosenberg, M. W., Mehnert, J. M., Guo, J. Y., Lattime, E., Rabinowitz, J. D. & White, E., Nov 22 2018, In : Nature. 563, 7732, p. 569-573 5 p.

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

64 Scopus citations

MTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation

Moloughney, J. G., Vega-Cotto, N. M., Liu, S., Patel, C., Kim, P. K., Wu, C. C., Albaciete, D., Magaway, C., Chang, A., Rajput, S., Su, X., Werlen, G. & Jacinto, E., Jan 1 2018, In : Journal of Biological Chemistry. 293, 42, p. 16464-16478 15 p.

Rutgers, The State University

Research output: Contribution to journalArticle

6 Scopus citations

Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

Liu, L., Su, X., Quinn, W. J., Hui, S., Krukenberg, K., Frederick, D. W., Redpath, P., Zhan, L., Chellappa, K., White, E., Migaud, M., Mitchison, T. J., Baur, J. A. & Rabinowitz, J. D., May 1 2018, In : Cell Metabolism. 27, 5, p. 1067-1080.e5

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

63 Scopus citations
2017

Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate

Oslund, R. C., Su, X., Haugbro, M., Kee, J. M., Esposito, M., David, Y., Wang, B., Ge, E., Perlman, D. H., Kang, Y., Muir, T. W. & Rabinowitz, J. D., Oct 1 2017, In : Nature Chemical Biology. 13, 10, p. 1081-1087 7 p.

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

12 Scopus citations

Chemical Basis for Deuterium Labeling of Fat and NADPH

Zhang, Z., Chen, L., Liu, L., Su, X. & Rabinowitz, J. D., Oct 18 2017, In : Journal of the American Chemical Society. 139, 41, p. 14368-14371 4 p.

Princeton University, Rutgers, The State University

Research output: Contribution to journalArticle

23 Scopus citations

Metabolite Spectral Accuracy on Orbitraps

Su, X., Lu, W. & Rabinowitz, J. D., Jun 6 2017, In : Analytical Chemistry. 89, 11, p. 5940-5948 9 p.

Princeton University

Research output: Contribution to journalArticle

50 Scopus citations
2014

Dph3 is an electron donor for Dph1-Dph2 in the first step of eukaryotic diphthamide biosynthesis

Dong, M., Su, X., Dzikovski, B., Dando, E. E., Zhu, X., Du, J., Freed, J. H. & Lin, H., Feb 5 2014, In : Journal of the American Chemical Society. 136, 5, p. 1754-1757 4 p.

Research output: Contribution to journalArticle

34 Scopus citations

Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis

Lin, Z., Su, X., Chen, W., Ci, B., Zhang, S. & Lin, H., Apr 30 2014, In : Journal of the American Chemical Society. 136, 17, p. 6179-6182 4 p.

Research output: Contribution to journalArticle

17 Scopus citations
2013

Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae

Kliegman, J. I., Fiedler, D., Ryan, C. J., Xu, Y. F., Su, X. Y., Thomas, D., Caccese, M. C., Cheng, A., Shales, M., Rabinowitz, J. D., Krogan, N. J. & Shokat, K. M., Dec 26 2013, In : Cell Reports. 5, 6, p. 1725-1736 12 p.

Princeton University

Research output: Contribution to journalArticle

19 Scopus citations
2012

Chemogenomic approach identified yeast YLR143W as diphthamide synthetase

Su, X., Lin, Z., Chen, W., Jiang, H., Zhang, S. & Lin, H., Dec 4 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 49, p. 19983-19987 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

YBR246W is required for the third step of diphthamide biosynthesis

Su, X., Chen, W., Lee, W., Jiang, H., Zhang, S. & Lin, H., Jan 18 2012, In : Journal of the American Chemical Society. 134, 2, p. 773-776 4 p.

Research output: Contribution to journalArticle

22 Scopus citations
2011

Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis

Zhu, X., Dzikovski, B., Su, X., Torelli, A. T., Zhang, Y., Ealick, S. E., Freed, J. H. & Lin, H., Jan 1 2011, In : Molecular BioSystems. 7, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

Du, J., Zhou, Y., Su, X., Yu, J. J., Khan, S., Jiang, H., Kim, J., Woo, J., Kim, J. H., Choi, B. H., He, B., Chen, W., Zhang, S., Cerione, R. A., Auwerx, J., Hao, Q. & Lin, H., Nov 11 2011, In : Science. 334, 6057, p. 806-809 4 p.

Rutgers, The State University

Research output: Contribution to journalArticle

687 Scopus citations
2010

Reconstitution of diphthine synthase activity in vitro

Zhu, X., Kim, J., Su, X. & Lin, H., Nov 9 2010, In : Biochemistry. 49, 44, p. 9649-9657 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Sequestration of copper from β-amyloid promotes selective lysis by cyclen-hybrid cleavage agents

Wu, W. H., Lei, P., Liu, Q., Hu, J., Gunn, A. P., Chen, M. S., Rui, Y. F., Su, X. Y., Xie, Z. P., Zhao, Y. F., Bush, A. I. & Li, Y. M., Nov 14 2008, In : Journal of Biological Chemistry. 283, 46, p. 31657-31664 8 p.

Research output: Contribution to journalArticle

94 Scopus citations
2007

Concise preparation of Nα-Fmoc-N ε-(Boc, methyl)-lysine and its application in the synthesis of site-specifically lysine monomethylated peptide

Huang, Z. P., Du, J. T., Su, X. Y., Chen, Y. X., Zhao, Y. F. & Li, Y. M., Jul 1 2007, In : Amino Acids. 33, 1, p. 85-89 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Hydrogen peroxide can be generated by tau in the presence of Cu(II)

Su, X. Y., Wu, W. H., Huang, Z. P., Hu, J., Lei, P., Yu, C. H., Zhao, Y. F. & Li, Y. M., Jun 29 2007, In : Biochemical and Biophysical Research Communications. 358, 2, p. 661-665 5 p.

Research output: Contribution to journalArticle

37 Scopus citations

Tyrosine phosphorylation/dephosphorylation regulates peroxynitrite-mediated peptide nitration

Shi, W. Q., Cai, H., Xu, D. D., Su, X. Y., Lei, P., Zhao, Y. F. & Li, Y. M., Dec 1 2007, In : Regulatory Peptides. 144, 1-3, p. 1-5 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2006

Facile synthesis of Nε-(benzyl, methyl)-lysine as a building block for site-specifically lysine monomethylated peptides

Huang, Z. P., Su, X. Y., Du, J. T., Zhao, Y. F. & Li, Y. M., Aug 14 2006, In : Tetrahedron Letters. 47, 33, p. 5997-5999 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of radiation-induced cross-linking between thymine and tryptophan by electrospray ionization-mass spectrometry

Shi, W. Q., Hu, J., Zhao, W., Su, X. Y., Cai, H., Zhao, Y. F. & Li, Y. M., Sep 1 2006, In : Journal of Mass Spectrometry. 41, 9, p. 1205-1211 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2004

Unassisted refolding of urea-denatured arginine kinase from shrimp Feneropenaeus chinensis: Evidence for two equilibrium intermediates in the refolding pathway

Pan, J. C., Yu, Z., Su, X. Y., Sun, Y. Q., Rao, X. M. & Zhou, H. M., Jul 1 2004, In : Protein Science. 13, 7, p. 1892-1901 10 p.

Research output: Contribution to journalArticle

19 Scopus citations