Zhihong Wang

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Education/Academic qualification

Doctor of Philosophy, doctorate, University of Utah

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Activation and Regulation Mechanisms of the RAF Kinase Family
Wang, Z.
National Institutes of Health (NIH)
6/4/22 → 8/31/25
Rowan University
Project: Other project

10 Article
2 Chapter
1 Review article

Mechanism and inhibition of BRAF kinase
Gunderwala, A., Cope, N. & Wang, Z., Dec 2022, In: Current Opinion in Chemical Biology. 71, 102205.
Rowan University
Research output: Contribution to journal › Review article › peer-review
Analyses of the oncogenic BRAF^D594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling
Cope, N. J., Novak, B., Liu, Z., Cavallo, M., Gunderwala, A. Y., Connolly, M. & Wang, Z., Feb 21 2020, In: Journal of Biological Chemistry. 295, 8, p. 2407-2420 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Biochemical Characterization of Full-Length Oncogenic BRAF^V600E together with Molecular Dynamics Simulations Provide Insight into the Activation and Inhibition Mechanisms of RAF Kinases
Cope, N., Novak, B., Candelora, C., Wong, K., Cavallo, M., Gunderwala, A., Liu, Z., Li, Y. & Wang, Z., Nov 18 2019, In: ChemBioChem. 20, 22, p. 2850-2861 12 p.
Research output: Contribution to journal › Article › peer-review
Development of Allosteric BRAF Peptide Inhibitors Targeting the Dimer Interface of BRAF
Gunderwala, A. Y., Nimbvikar, A. A., Cope, N. J., Li, Z. & Wang, Z., Jun 3 2019, In: ACS chemical biology. 14, 7, p. 1471-1480 10 p.
Research output: Contribution to journal › Article › peer-review
Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase
Wang, Z., Kim, M. S., Martinez-Ferrando, I., Koleske, A. J., Pandey, A. & Cole, P. A., Feb 27 2018, In: Biochemistry. 57, 8, p. 1390-1398 9 p.
Research output: Contribution to journal › Article › peer-review

Zhihong Wang

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Activation and Regulation Mechanisms of the RAF Kinase Family

Mechanism and inhibition of BRAF kinase

Analyses of the oncogenic BRAF^D594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling

Biochemical Characterization of Full-Length Oncogenic BRAF^V600E together with Molecular Dynamics Simulations Provide Insight into the Activation and Inhibition Mechanisms of RAF Kinases

Development of Allosteric BRAF Peptide Inhibitors Targeting the Dimer Interface of BRAF

Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase

Zhihong Wang

Personal profile

Education/Academic qualification

Fingerprint

Network

Projects

Activation and Regulation Mechanisms of the RAF Kinase Family

Research output

Mechanism and inhibition of BRAF kinase

Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling

Biochemical Characterization of Full-Length Oncogenic BRAFV600E together with Molecular Dynamics Simulations Provide Insight into the Activation and Inhibition Mechanisms of RAF Kinases

Development of Allosteric BRAF Peptide Inhibitors Targeting the Dimer Interface of BRAF

Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase

Analyses of the oncogenic BRAF^D594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling

Biochemical Characterization of Full-Length Oncogenic BRAF^V600E together with Molecular Dynamics Simulations Provide Insight into the Activation and Inhibition Mechanisms of RAF Kinases