Project Details


A pediatric AIDS Clinical Study Group (CSG) will be established
at the UMDNJ-NJMS and Children's Hospital of New Jersey. The
goals of this program include: 1) to conduct clinical trials of new
and improved treatments for HTLV-III/LAV infection in children;
2) to conduct research designed to compliment treatment trails
and 3) to implement outreach educational programs. It is
anticipated that this pediatric AIDS CSG will function as a
member of a pediatric sub-network within the total CSG network.
The organization structure of this CSG will include a principal
investigator and three research investigators who will be
responsible for the accomplishments of the aforementioned three
major program goals. The primary focus of clinical trails to be performed in this
pediatric CSG proposal will be anti viral chemotherapy. The basic
research component will compliment treatment trails and include
studies on methods for screening, diagnosis and monitoring of
children with HTLV-III/LAV infection. The educational outreach
component will be specifically targeted to the professional
education of physicians and nurses regarding diagnosis, treatment
and care of infants and children with HTLV-III/LAV infection. Patients to be enrolled in this proposed program will be recruited
from established programs in the Network metropolitan area.
These include the Children's Hospital AIDS Program (CHAP), a
defined cohort of infants from an ongoing study of the natural
history of HTLV/III/LAV infection and from the regional
hemophilia care program. These sources will provide sufficient
case material to accomplish the goals of the CSG network
treatment program.Description
Effective start/end date9/30/872/28/07


  • National Institutes of Health: $904,264.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health


  • Medicine(all)
  • Immunology and Microbiology(all)

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