Project Details


The mission of the Center for Environmental Exposure and Disease (CEED) is to improve human health byperforming transdisciplinary research to elucidate how the total environment, the genome and the epigenomeinteract to mitigate the risk of disease. CEED research focuses on: 1) assessing and modeling exposures, 2)discovering and applying biological response indicators which link exposures to mechanisms of pathogenesis,3) developing and implementing targeted prevention, intervention, and treatment strategies, 4) reducingexposures by influencing public policy, planning and regulation, and 5) engaging and informing stakeholders.By analogy with Precision Medicine, CEED envisions that the integration of data from exposure biology,genomics, epigenetics and microbiomics to assess exposures, biological responses, mechanisms ofpathogenesis and disease prevention will significantly impact the future of environmental health. The CEEDvision is to lead the development of precision environmental health research through the integration of clinical,basic, and population-based studies, using the acquired information to prevent and/or treat environmentaldisease. The strategy is to combine the Center's long-standing breadth and depth of expertise inenvironmental health research with new capabilities in exposure biology, epigenomics, and microbiomics. TheSpecific Aims are: Aim 1: Move basic, clinical and population research toward precision environmental healthby: i) fostering a collaborative, transdisciplinary research environment, ii) supporting innovative research andemerging science through Pilot grant funding, and iii) providing cost-effective access to Facility Cores thatmaintain state-of-the-art technologies and expertise. Aim 2: Provide training and mentoring opportunities tojunior investigators and established researchers in innovative and emerging environmental health researchthrough: i) mentoring committees and a structured mentoring curriculum, ii) collaborative research, iii) CareerDevelopment Awards and Pilot Project grants, and iv) opportunities for expanded training with other NIEHSCenters. Aim 3: Strengthen and expand existing relationships with community partners by: i) facilitatingbidirectional interactions among CEED researchers and community partners to identify environmentalconcerns and desired outcomes, ii) developing research programs that address community health needs, andiii) providing research results, educational materials and expertise to communities and health professionals,enabling them to minimize exposures and influence public health policy. Aim 4: Translate research findings tostakeholders in local, state and federal government agencies to provide guidance on mitigation of risk, toinfluence public policy, and to support legislation that reduces exposure and improve environmental health.
Effective start/end date7/29/144/2/15


  • National Institutes of Health (NIH)

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