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The Regulation of Cell Metabolism and Proliferation by mTOR complex 2
Jacinto, Estela
(PI)
Jacinto, Estela
(PI)
Robert Wood Johnson Medical School (RWJMS), Biochemistry & Molecular Biology
Rutgers, The State University
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Medicine & Life Sciences
Adenosine Triphosphate
11%
Apoptosis
7%
Biosynthetic Pathways
54%
Carcinogenesis
11%
Cell Proliferation
50%
Cell Survival
68%
Enzymes
8%
Glucose
18%
Glycolysis
31%
Growth
24%
Growth Factor Receptors
17%
Mechanistic Target of Rapamycin Complex 2
39%
Membrane Proteins
12%
Metabolic Networks and Pathways
30%
Neoplasms
42%
Nucleotides
12%
Pharmaceutical Preparations
10%
Phosphatidylinositol 3-Kinases
14%
Phosphorylation
61%
Protein Kinases
11%
Protein Stability
15%
Proteins
8%
Signal Transduction
11%
Sirolimus
95%
TOR Serine-Threonine Kinases
100%
Type 1 Diabetes Mellitus
26%
Up-Regulation
18%