A novel wave reflection model of the human arterial system

TY - JOUR

T1 - A novel wave reflection model of the human arterial system

AU - Zhang, Hongjun

AU - Li, John K.J.

PY - 2009/6

Y1 - 2009/6

N2 - A frequency domain distributed 55 segment arterial model was constructed from the reflection perspective to predict pressure waveforms in the large systemic arteries. At any node, the predicted pressure waveform was the combination of a forward propagating waveform and a number of repeatedly reflected waveforms from any possible sites. This approach ensured that any single reflected waveform could be traced back to its origin, and thus the causal-effect relation would be precisely known. This model was evaluated in terms of branch reflection coefficient, terminal vascular bed behavior, and wall viscoelasticity. It was found that the model predicted pressure waveforms were most sensitive to the branch reflection coefficient, and this led to the adoption of the zero-forward reflection assumption at branches. The model-predicted pressure waveforms compared favorably with realistic blood pressure waveforms, especially in the upper limbs. For lower limbs, finer segmentation could further improve the predictions.

AB - A frequency domain distributed 55 segment arterial model was constructed from the reflection perspective to predict pressure waveforms in the large systemic arteries. At any node, the predicted pressure waveform was the combination of a forward propagating waveform and a number of repeatedly reflected waveforms from any possible sites. This approach ensured that any single reflected waveform could be traced back to its origin, and thus the causal-effect relation would be precisely known. This model was evaluated in terms of branch reflection coefficient, terminal vascular bed behavior, and wall viscoelasticity. It was found that the model predicted pressure waveforms were most sensitive to the branch reflection coefficient, and this led to the adoption of the zero-forward reflection assumption at branches. The model-predicted pressure waveforms compared favorably with realistic blood pressure waveforms, especially in the upper limbs. For lower limbs, finer segmentation could further improve the predictions.

KW - Arterial hemodynamics

KW - Blood pressure waveforms

KW - Distributed model

KW - Pulse wave propagation

KW - Pulse wave reflection

UR - https://www.scopus.com/pages/publications/67650604367

UR - https://www.scopus.com/inward/citedby.url?scp=67650604367&partnerID=8YFLogxK

U2 - 10.1007/s10558-009-9074-3

DO - 10.1007/s10558-009-9074-3

M3 - Article

C2 - 19495973

SN - 1567-8822

VL - 9

SP - 39

EP - 48

JO - Cardiovascular Engineering

JF - Cardiovascular Engineering

IS - 2

ER -