@inbook{ab504d50b38b438287eab2a98bd26f1f,
title = "A quantitative approach to understand raw material variability",
abstract = "The properties of raw materials can affect the properties and quality of intermediates and the final product. The flow behavior of powders, the form of the raw materials for solid oral drug product manufacturing processes, is poorly understood. Thus, the prediction of manufacturability and process performance is difficult. This is further complicated with variability in raw material flow properties. This chapter discusses seven properties typically characterized and the techniques used to measure them. The state of the art in applying this information to define a formulation of manufacturing process is also discussed.",
keywords = "Characterization, Flowability, Powder",
author = "Sara Koynov and Muzzio, {Fernando J.}",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2015.",
year = "2016",
month = jan,
day = "1",
doi = "10.1007/978-1-4939-2996-2_3",
language = "English (US)",
series = "Methods in Pharmacology and Toxicology",
publisher = "Humana Press Inc.",
pages = "85--104",
booktitle = "Methods in Pharmacology and Toxicology",
}