A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells

Andreas Kurtz, Stefanie Seltmann, Amos Bairoch, Marie Sophie Bittner, Kevin Bruce, Amanda Capes-Davis, Laura Clarke, Jeremy M. Crook, Laurence Daheron, Johannes Dewender, Adam Faulconbridge, Wataru Fujibuchi, Alexander Gutteridge, Derek J. Hei, Yong Ou Kim, Jung Hyun Kim, Anja Kolb Kokocinski, Fritz Lekschas, Geoffrey P. Lomax, Jeanne F. LoringTenneille Ludwig, Nancy Mah, Tohru Matsui, Robert Müller, Helen Parkinson, Michael Sheldon, Kelly Smith, Harald Stachelscheid, Glyn Stacey, Ian Streeter, Anna Veiga, Ren He Xu

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Unambiguous cell line authentication is essential to avoid loss of association between data and cells. The risk for loss of references increases with the rapidity that new human pluripotent stem cell (hPSC) lines are generated, exchanged, and implemented. Ideally, a single name should be used as a generally applied reference for each cell line to access and unify cell-related information across publications, cell banks, cell registries, and databases and to ensure scientific reproducibility. We discuss the needs and requirements for such a unique identifier and implement a standard nomenclature for hPSCs, which can be automatically generated and registered by the human pluripotent stem cell registry (hPSCreg). To avoid ambiguities in PSC-line referencing, we strongly urge publishers to demand registration and use of the standard name when publishing research based on hPSC lines. In this article Kurtz, Seltmann and colleagues propose a standard nomenclature and registry for human pluripotent stem cells. The nomenclature is based on fixed name elements and provides a unique identifier for PSC lines suitable for referencing over diverse data sources, registries, publications, and cell banks. Rigorous application is needed to reduce risks from misidentification and false referencing of lines and data.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalStem Cell Reports
Issue number1
StatePublished - 2018

All Science Journal Classification (ASJC) codes

  • Genetics
  • Biochemistry
  • Cell Biology
  • Developmental Biology


  • cell data referencing
  • cell databases
  • cell line authentication
  • cell line nomenclature
  • human pluripotent stem cells
  • stem cell registry


Dive into the research topics of 'A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells'. Together they form a unique fingerprint.

Cite this