Advances in Charcot-Marie-Tooth disease research: Cellular function of CMT-related proteins, transgenic animal models, and pathomechanisms

Hans W. Müller, Ueli Suter, Christine Van Broeckhoven, O. Haneman, E. Nelis, V. Timmerman, S. Sancho, L. Barrio, P. Bolhuis, R. Dermietzel, M. Frank, A. Gabreëls-Festen, C. Gillen, N. Haites, G. Levi, E. Mariman, R. Martini, K. Nave, B. Rautenstrauss, M. SchachnerA. Schenone, C. Schneider, M. Schröder, K. Willecke

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The First Workshop of the European Consortium on Charcot-Marie-Tooth (CMT) disease brought together neuroscientists, molecular and cell biologists, neuropathologists, neurologists, and geneticists with a common interest in the understanding of the fundamental mechanisms that underlie the pathogenesis of CMT. The interdisciplinary group of 25 expert scientists discussed recent advances in (i) molecular genetics and histopathology of CMT, (ii) development of suitable animal models, (iii) understanding of the cellular function of CMT-related proteins, and (iv) studies using nerve biopsies from CMT patients. In this minireview, we summarize the key findings presented and discuss their impact on CMT research.

Original languageEnglish (US)
Pages (from-to)215-220
Number of pages6
JournalNeurobiology of Disease
Volume4
Issue number3-4
DOIs
StatePublished - 1997

All Science Journal Classification (ASJC) codes

  • Neurology

Fingerprint

Dive into the research topics of 'Advances in Charcot-Marie-Tooth disease research: Cellular function of CMT-related proteins, transgenic animal models, and pathomechanisms'. Together they form a unique fingerprint.

Cite this