Alkaloids of the Mexican Bean Beetle, Epilachna varivestis (Coccinellidae)

Athula B. Attygalle, Shang Cheng Xu, Kevin D. McCormick, Jerrold Meinwald, Curtis L. Blankespoor, Thomas Eisner

Research output: Contribution to journalArticlepeer-review


Two novel alkaloids, 2-(12-aminotridecyl)-pyrrolidine and its 1-(2-hydroxyethyl) derivative, are characterized from extracts of adult Mexican bean beetles. These pyrrolidines, together with a previously identified homotropane alkaloid, euphococcinine, account for 90% of the alkaloids present in this beetle. A number of piperidine derivatives are also identified as minor components. The total mixture represents the most complex bouquet of alkaloids reported hitherto from any coccinellid beetle.

Original languageEnglish
Pages (from-to)9333-9342
Number of pages10
Issue number41
StatePublished - 1993

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this