Altered acceptability of and preference for sugar solutions by diabetic rats is normalized by high-fat diet

Beverly J. Tepper, Mark I. Friedman

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Two experiments examined the ingestive responses of streptozotocin-diabetic rats fed low-fat or high-fat diets to glucose, fructose, sucrose and maltose solutions in brief (30 min) intake tests. In Experiment 1, one-bottle acceptability tests were used whereas two-bottle preference tests were used in Experiment 2. Three main findings resulted from these studies. Firstly, diabetic rats fed the low-fat diet displayed a reduced acceptance of and preference for all concentrated sugar solutions. Secondly, glucose consumption patterns of diabetic rats fed the low-fat diet were distinctly different from their responses to the other sugars. Thirdly feeding high-fat diets, either high or low in carbohydrate, normalized the responses of diabetic rats to the sugar solutions. The results suggest that feeding high-fat diets to diabetic rats normalizes their responses to sugar solutions because of reductions in hunger and thirst associated with the provision of a utilizable source of calories and an improvement in body fluid balance.

Original languageEnglish (US)
Pages (from-to)25-38
Number of pages14
JournalAppetite
Volume16
Issue number1
DOIs
StatePublished - Feb 1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Psychology(all)
  • Nutrition and Dietetics

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