Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1

Jeffrey S. Smith, Sunyoung Kim, Monica J. Roth

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Circle junctions of unintegrated human immunodeficiency virus type 1strain IIIB were analysed after polymerase chain reaction amplification. Among the 28 colonies sequenced eight unique circle junction species were detected. Five of the eight species resulted in circle junctions with larger inserts than predicted. A majority of these could results from heterogeneity in generating the U5′ long terminal repeat terminus.

Original languageAmerican English
Pages (from-to)6286-6290
Number of pages5
JournalJournal of virology
Volume64
Issue number12
StatePublished - 1990

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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