Assessment of Vascular Reactivity

P. A. Stapleton, A. B. Abukabda, J. C. Frisbee, M. A. Boegehold, T. R. Nurkiewicz

Research output: Chapter in Book/Report/Conference proceedingChapter


Vascular reactivity encompasses many types of responses, under many conditions, in virtually every tissue, a multitude of experimental techniques exist to assess vascular reactivity. This chapter will focus exclusively upon alterations in vessel caliber, and its greater purpose is threefold. First, the appropriate organizational levels of the vasculature to properly characterize vascular reactivity will be identified. Second, common techniques of vascular reactivity assessment will be discussed and compared. Third, alterations in vascular reactivity and their impacts on hemodynamics will be discussed.

Original languageEnglish (US)
Title of host publicationCardiovascular Toxicology
PublisherElsevier Inc.
Number of pages12
ISBN (Electronic)9780081006122
ISBN (Print)9780081006016
StatePublished - Jan 1 2018

ASJC Scopus subject areas

  • Medicine(all)


  • Endothelium
  • In vitro
  • In vivo
  • Pressure
  • Shear stress
  • Smooth muscle
  • Vascular techniques
  • Vasoconstriction
  • Vasodilation
  • Wall tension


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