Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRASG12D-driven lung tumors

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Abstract

FAO, fatty acid oxidation; FAs, fatty acids; GEMMs, genetically engineered mouse models; NSCLC, nonsmall- cell lung cancer; TDCLs, tumorderived cell lines; TCA, tricarboxylic acid.

Original languageEnglish (US)
Pages (from-to)1636-1638
Number of pages3
JournalAutophagy
Volume9
Issue number10
DOIs
StatePublished - Oct 2013

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

Keywords

  • Autophagy
  • Fatty acid oxidation
  • KRAS
  • Metabolism
  • Mitochondria
  • NSCLC
  • Oncocytoma
  • P53

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