Abstract
The rationale for a degradable bioactive glass coating is to lead the bone to appose gradually to the metal. Two formulations of bioactive glasses, already described in the literature, have been studied: bg A and bg F. A sodium-calcium-silicate non-bioactive glass was sprayed as a control. Young adult New Zealand White rabbits were selected as animal model. A hole was drilled from the femural intercondylar groove and a Ti6Al4V coated cylinder was implanted. Retrievals took place at 1, 2, 4, 6, 8, 10 months. For all the samples and for both preparations of bioactive glass, it was noticed that bone was in tight apposition with the coating. As time progressed, pictures were found where bone showed characters of physiological remodelling (newly formed bone substituting areas of bone resorption) close to the coating. At the interface between bone and bioactive glass coating the apposition was so tight that it was not possible to discern a clear demarcation, even at higher BSEM magnification (more than 2500X). A second key feature in the behaviour of the bioactive glass coatings was their gradual degradation and the eventual apposition of bone directly to Ti6Al4V.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 789-792 |
| Number of pages | 4 |
| Journal | Key Engineering Materials |
| Volume | 254-256 |
| State | Published - 2004 |
| Externally published | Yes |
| Event | The Annual Meeting of the International Society for Ceramics in Medicine - Porto, Portugal Duration: Nov 6 2003 → Nov 9 2003 |
All Science Journal Classification (ASJC) codes
- General Materials Science
- Mechanics of Materials
- Mechanical Engineering
Keywords
- Bioactive glass
- Bone tissue
- Coatings
- In-vivo study