Brain and sperm cell surface antigen (NS-4) on preimplantation mouse embryos

Davor Solter, Melitta Camartin

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Antiserum prepared in rabbit against 4-day-old mouse cerebellum (anti-NS-4 serum) reacts in the complement-mediated cytotoxicity test with unfertilized and fertilized mouse eggs, cleavage stage embryos, and cells of the trophoblast and inner cell mass of the mouse blastocyst. This activity is specifically removed by absorption of antiserum with adult mouse brain and epididymal sperm but not with adult liver, spleen, kidney, and thymocytes. The antiserum reacts most strongly with cells of the trophoblast and inner cell mass and, in order of decreasing reactivity, with four- to eight-cell stage embryos, zygotes, unfertilized eggs, and two-cell stage embryos.

Original languageEnglish (US)
Pages (from-to)98-104
Number of pages7
JournalDevelopmental biology
Volume52
Issue number1
DOIs
StatePublished - Jan 1 1976

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Blastocyst
Surface Antigens
Spermatozoa
Brain
Immune Sera
Embryonic Structures
Zygote
Trophoblasts
Blastocyst Inner Cell Mass
Thymocytes
Cerebellum
Ovum
Spleen
Rabbits
Kidney
Liver
Serum

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology
  • Developmental Biology

Cite this

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Brain and sperm cell surface antigen (NS-4) on preimplantation mouse embryos. / Solter, Davor; Camartin, Melitta.

In: Developmental biology, Vol. 52, No. 1, 01.01.1976, p. 98-104.

Research output: Contribution to journalArticle

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