Abstract
Osteoarthritis, the severe degeneration of articular surfaces, affects approximately 27 million people in the United States, causing pain and discomfort. Current treatments are inadequate and often result in long-term reinjury. This chapter discusses how tissue engineering aims to address these inadequacies in three categories: the induction of cartilage's biological properties, the choice of materials, and other considerations, including lateral integration and surface friction.
Original language | American English |
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Title of host publication | Regenerative Engineering of Musculoskeletal Tissues and Interfaces |
Publisher | Elsevier Inc. |
Pages | 135-160 |
Number of pages | 26 |
ISBN (Electronic) | 9781782423140 |
ISBN (Print) | 9781782423010 |
DOIs | |
State | Published - Apr 23 2015 |
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
Keywords
- Articular cartilage
- Autologous chondrocyte implantation (ACI)
- Polymers
- Stem cells