Caseum: A niche for mycobacterium tuberculosis drug-tolerant persisters

Keyphrases

• Mycobacterium Tuberculosis (M. tb) 100%
• Tuberculosis Drugs 100%
• Drug-tolerant Persisters 100%
• Caseum 100%
• Oxygen Tension 25%
• Drug Tolerance 16%
• Nodule 16%
• Knowledge Gaps 8%
• Macrophages 8%
• Lipid Species 8%
• Avascular 8%
• Low Oxygen 8%
• Mycobacterium 8%
• Tuberculosis Patients 8%
• Paucity 8%
• Microenvironment 8%
• Nutrient Deprivation 8%
• Autopsy 8%
• Airway 8%
• Acidic pH 8%
• Stress Factors 8%
• Lipid Droplets 8%
• Lipid-rich 8%
• Specific Stresses 8%
• Cavity Surface 8%
• Open Cavity 8%
• Foamy Macrophages 8%
• Drug Screening Assays 8%
• Near-neutral 8%
• Non-persistence 8%
• Tuberculous Lesions 8%
• High-throughput Drug Discovery 8%
• Cavity Wall 8%
• Lipid Abundance 8%
• Knowledge State 8%

Medicine and Dentistry

• Mycobacterium Tuberculosis 100%
• Tuberculosis 100%
• Macrophage 40%
• Drug Tolerance 40%
• Lipid 40%
• Mycobacteria 20%
• Fat Droplet 20%
• High Fat Food 20%

Immunology and Microbiology

• Mycobacterium Tuberculosis 100%
• Oxygen Tension 100%
• Macrophage 50%
• Drug Tolerance 50%
• Mycobacteria 25%
• Airway 25%
• Replication 25%