Characterization and modeling of the in-plane collagen fiber distribution in the porcine dermis

Suman Jaiswal, Rama Hannineh, Samuel Lieber, Shawn A. Chester

Research output: Contribution to journalArticlepeer-review

Abstract

The structural arrangement of collagen fibers in the plane of the dermis layer plays a critical role in accurately predicting the mechanical behavior of skin tissues. This paper combines a histological analysis with statistical modeling to characterize and model the in-plane collagen fiber distribution in the porcine dermis. The histology data reveals that the fiber distribution in the plane of the porcine dermis is non-symmetric. The histology data forms the basis of our model, which employs a combination of two π-periodic von-Mises distribution density functions to create a non-symmetric distribution.

Original languageEnglish (US)
Article number103973
JournalMedical Engineering and Physics
Volume115
DOIs
StatePublished - May 2023

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering

Keywords

  • Anisotropic
  • Collagen
  • Histology
  • Non-symmetric distribution
  • Porcine dermis
  • Tissue

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