TY - JOUR
T1 - Chemical composition of alkaloids of Plumula nelumbinis and their antioxidant activity from different habitats in China
AU - Tian, Wenyue
AU - Zhi, Hui
AU - Yang, Chao
AU - Wang, Likang
AU - Long, Jiatang
AU - Xiao, Luomin
AU - Liang, Jizheng
AU - Huang, Ying
AU - Zheng, Xi
AU - Zhao, Suqing
AU - Zhang, Kun
AU - Zheng, Junxia
N1 - Funding Information: This study was supported by a research grant from the National Natural Science Fund of China (No. 81303201 , 81773593 ), the Excellent Young Teachers Program of Guangdong Provincial Colleges and Universities ( YQ 2015061 ), the Pearl River S&T Nova Program of Guangzhou ( 201610010100 ), Science and Technology Program of Guangzhou ( 201707010414 ). Funding Information: This study was supported by a research grant from the National Natural Science Fund of China (No. 81303201, 81773593), the Excellent Young Teachers Program of Guangdong Provincial Colleges and Universities (YQ 2015061), the Pearl River S&T Nova Program of Guangzhou (201610010100), Science and Technology Program of Guangzhou (201707010414). Publisher Copyright: © 2018 Elsevier B.V.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - The aim of this study was to investigate the alkaloids in Plumula nelumbinis collected in the Xiangtan, Hunan province and to compare the antioxidant activity of total alkaloids fraction from Plumula nelumbinis collected from thirteen different locations in China. By comparing the retention times, mass spectrometry fragmentation ions, molecular formulas and molecular weights of the components with those of standards and reference compounds, a total of thirty alkaloids belonging to the benzylisoquinoline, bisbenzylisoquinoline, aporphine, proaporphine, isoquinolines alkaloid families were identified based on a sensitive and efficient ultra-performance liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry method. Six alkaloids were detected for the first time in Nelumbo and fourteen alkaloids were detected for the first time in Plumula nelumbinis. Two compounds, which named as isococlaurine-5′-O-pentoside and coclaurine-5′-O-pentoside, were characterized and identified as new compounds. The antioxidant activity of the total alkaloids collected from thirteen locations was determined by three standard assays. It was shown that Anhuibozhou province produces plants with the strongest antioxidant activity measured in the three assays, and was followed by Yunnanwenshan. Shandongweihu has the strongest oxygen radical absorbance capacity, Zhejianghangzhou produces plants with the strongest ferric reducing ability and Jiangxishicheng plants have the strongest radical-scavenging activity. By and large, a positive correlation between the alkaloid content and antioxidant activity was found. Plumula nelumbinis samples from different habitats that have antioxidant activities may be alternatives to synthetic antioxidants in the food industry.
AB - The aim of this study was to investigate the alkaloids in Plumula nelumbinis collected in the Xiangtan, Hunan province and to compare the antioxidant activity of total alkaloids fraction from Plumula nelumbinis collected from thirteen different locations in China. By comparing the retention times, mass spectrometry fragmentation ions, molecular formulas and molecular weights of the components with those of standards and reference compounds, a total of thirty alkaloids belonging to the benzylisoquinoline, bisbenzylisoquinoline, aporphine, proaporphine, isoquinolines alkaloid families were identified based on a sensitive and efficient ultra-performance liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry method. Six alkaloids were detected for the first time in Nelumbo and fourteen alkaloids were detected for the first time in Plumula nelumbinis. Two compounds, which named as isococlaurine-5′-O-pentoside and coclaurine-5′-O-pentoside, were characterized and identified as new compounds. The antioxidant activity of the total alkaloids collected from thirteen locations was determined by three standard assays. It was shown that Anhuibozhou province produces plants with the strongest antioxidant activity measured in the three assays, and was followed by Yunnanwenshan. Shandongweihu has the strongest oxygen radical absorbance capacity, Zhejianghangzhou produces plants with the strongest ferric reducing ability and Jiangxishicheng plants have the strongest radical-scavenging activity. By and large, a positive correlation between the alkaloid content and antioxidant activity was found. Plumula nelumbinis samples from different habitats that have antioxidant activities may be alternatives to synthetic antioxidants in the food industry.
KW - Alkaloids
KW - Antioxidant
KW - Plumula nelumbinis
KW - UPLC-ESI-QTOF-MS
UR - http://www.scopus.com/inward/record.url?scp=85054019634&partnerID=8YFLogxK
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U2 - https://doi.org/10.1016/j.indcrop.2018.09.045
DO - https://doi.org/10.1016/j.indcrop.2018.09.045
M3 - Article
VL - 125
SP - 537
EP - 548
JO - Industrial Crops and Products
JF - Industrial Crops and Products
SN - 0926-6690
ER -