Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care

Salma K. Jabbour; Ritesh Kumar; Bethany Anderson; Junzo P. Chino; Krishan R. Jethwa; Lachlan McDowell; Andrea C. Lo; Dawn Owen; Erqi L. Pollom; Alison C. Tree; Derek S. Tsang; Sue S. Yom

doi:10.1016/j.ijrobp.2024.01.010

Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care

Salma K. Jabbour, Ritesh Kumar, Bethany Anderson, Junzo P. Chino, Krishan R. Jethwa, Lachlan McDowell, Andrea C. Lo, Dawn Owen, Erqi L. Pollom, Alison C. Tree, Derek S. Tsang, Sue S. Yom

Cancer Institute of New Jersey (CINJ), Radiation Oncology

Rutgers, The State University

Research output: Contribution to journal › Review article › peer-review

Abstract

Combinatorial therapies consisting of radiation therapy (RT) with systemic therapies, particularly chemotherapy and targeted therapies, have moved the needle to augment disease control across nearly all disease sites for locally advanced disease. Evaluating these important combinations to incorporate more potent therapies with RT will aid our understanding of toxicity and efficacy for patients. This article discusses multiple disease sites and includes a compilation of contributions from expert Red Journal editors from each disease site. Leveraging improved systemic control with novel agents, we must continue efforts to study novel treatment combinations with RT.

Original language	English (US)
Pages (from-to)	1240-1261
Number of pages	22
Journal	International Journal of Radiation Oncology Biology Physics
Volume	118
Issue number	5
DOIs	https://doi.org/10.1016/j.ijrobp.2024.01.010
State	Published - Apr 1 2024

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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10.1016/j.ijrobp.2024.01.010

Cite this

Jabbour, S. K., Kumar, R., Anderson, B., Chino, J. P., Jethwa, K. R., McDowell, L., Lo, A. C., Owen, D., Pollom, E. L., Tree, A. C., Tsang, D. S., & Yom, S. S. (2024). Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care. International Journal of Radiation Oncology Biology Physics, 118(5), 1240-1261. https://doi.org/10.1016/j.ijrobp.2024.01.010

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title = "Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care",

abstract = "Combinatorial therapies consisting of radiation therapy (RT) with systemic therapies, particularly chemotherapy and targeted therapies, have moved the needle to augment disease control across nearly all disease sites for locally advanced disease. Evaluating these important combinations to incorporate more potent therapies with RT will aid our understanding of toxicity and efficacy for patients. This article discusses multiple disease sites and includes a compilation of contributions from expert Red Journal editors from each disease site. Leveraging improved systemic control with novel agents, we must continue efforts to study novel treatment combinations with RT.",

author = "Jabbour, {Salma K.} and Ritesh Kumar and Bethany Anderson and Chino, {Junzo P.} and Jethwa, {Krishan R.} and Lachlan McDowell and Lo, {Andrea C.} and Dawn Owen and Pollom, {Erqi L.} and Tree, {Alison C.} and Tsang, {Derek S.} and Yom, {Sue S.}",

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year = "2024",

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doi = "10.1016/j.ijrobp.2024.01.010",

language = "English (US)",

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Jabbour, SK, Kumar, R, Anderson, B, Chino, JP, Jethwa, KR, McDowell, L, Lo, AC, Owen, D, Pollom, EL, Tree, AC, Tsang, DS & Yom, SS 2024, 'Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care', International Journal of Radiation Oncology Biology Physics, vol. 118, no. 5, pp. 1240-1261. https://doi.org/10.1016/j.ijrobp.2024.01.010

Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care. / Jabbour, Salma K.; Kumar, Ritesh; Anderson, Bethany et al.
In: International Journal of Radiation Oncology Biology Physics, Vol. 118, No. 5, 01.04.2024, p. 1240-1261.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation

T2 - United Efforts to Innovate in Patient Care

AU - Jabbour, Salma K.

AU - Kumar, Ritesh

AU - Anderson, Bethany

AU - Chino, Junzo P.

AU - Jethwa, Krishan R.

AU - McDowell, Lachlan

AU - Lo, Andrea C.

AU - Owen, Dawn

AU - Pollom, Erqi L.

AU - Tree, Alison C.

AU - Tsang, Derek S.

AU - Yom, Sue S.

PY - 2024/4/1

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N2 - Combinatorial therapies consisting of radiation therapy (RT) with systemic therapies, particularly chemotherapy and targeted therapies, have moved the needle to augment disease control across nearly all disease sites for locally advanced disease. Evaluating these important combinations to incorporate more potent therapies with RT will aid our understanding of toxicity and efficacy for patients. This article discusses multiple disease sites and includes a compilation of contributions from expert Red Journal editors from each disease site. Leveraging improved systemic control with novel agents, we must continue efforts to study novel treatment combinations with RT.

AB - Combinatorial therapies consisting of radiation therapy (RT) with systemic therapies, particularly chemotherapy and targeted therapies, have moved the needle to augment disease control across nearly all disease sites for locally advanced disease. Evaluating these important combinations to incorporate more potent therapies with RT will aid our understanding of toxicity and efficacy for patients. This article discusses multiple disease sites and includes a compilation of contributions from expert Red Journal editors from each disease site. Leveraging improved systemic control with novel agents, we must continue efforts to study novel treatment combinations with RT.

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DO - 10.1016/j.ijrobp.2024.01.010

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SN - 0360-3016

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JO - International Journal of Radiation Oncology Biology Physics

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Combinatorial Approaches for Chemotherapies and Targeted Therapies With Radiation: United Efforts to Innovate in Patient Care

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