Complications leading to surgery after breast implantation

Sherine Gabriel, John E. Woods, W. Michael O'Fallon, C. Mary Beard, Leonard T. Kurland, L. Joseph Melton

Research output: Contribution to journalArticle

308 Citations (Scopus)

Abstract

Background: Local complications that require additional surgical procedures are an important problem for women with breast implants. Methods: We studied 749 women who lived in Olmsted County, Minnesota, and received a first breast implant at the Mayo Clinic between 1964 and 1991. We identified complications that occurred after the initial procedure and after any subsequent implantation. A complication was defined as a surgical procedure performed for any of the following reasons: capsular contracture; rupture of the implant; hematoma or bleeding; infection or seroma of the wound; chronic pain; extrusion, leakage, or sweating of the implant; necrosis of the nipple, areola, or flap; malfunction of the filler port of a tissue expander; and wound dehiscence. Results: During follow-up (mean, 7.8 years; range, 0 to 25.8), 208 (27.8 percent) of the women underwent 450 additional implant- related surgical procedures. Ninety-one (20.2 percent) were anticipated, staged procedures or were done because the patient requested a size change or aesthetic improvement, and 359 procedures (79.8 percent) had at least one clinical indication (thus constituting a complication). Complications occurred in 178 (23.8 percent) of the 749 women and involved 274 (18.8 percent) of the 1454 breasts with implants and 321 (18.8 percent) of the 1703 implants. The most frequent problem was capsular contraction (131 women), followed by implant rupture (43 [5.7 percent]), hematoma (43), and wound infection (19). The rate of complications was significantly lower (P<0.001) among women with cosmetic implants (6.5 percent at one year, 12 percent at five years) than among those who received implants after mastectomy for breast cancer (21.8 percent at one year, 34 percent at five years) or prophylactic mastectomy (17.3 percent at one year, 30.4 percent at five years). Conclusions: Women who have had breast implantation frequently experience local complications during the subsequent five years. Complications were significantly less frequent among patients who received implants for cosmetic reasons than among those who received implants after mastectomy for cancer or for cancer prophylaxis.

Original languageEnglish (US)
Pages (from-to)677-682
Number of pages6
JournalNew England Journal of Medicine
Volume336
Issue number10
DOIs
StatePublished - Mar 6 1997

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Breast Implantation
Breast Implants
Nipples
Mastectomy
Cosmetics
Hematoma
Rupture
Tissue Expansion Devices
Seroma
Sweating
Wounds and Injuries
Contracture
Wound Infection
Esthetics
Chronic Pain
Neoplasms
Necrosis
Breast Neoplasms
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Gabriel, S., Woods, J. E., O'Fallon, W. M., Beard, C. M., Kurland, L. T., & Melton, L. J. (1997). Complications leading to surgery after breast implantation. New England Journal of Medicine, 336(10), 677-682. https://doi.org/10.1056/NEJM199703063361001
Gabriel, Sherine ; Woods, John E. ; O'Fallon, W. Michael ; Beard, C. Mary ; Kurland, Leonard T. ; Melton, L. Joseph. / Complications leading to surgery after breast implantation. In: New England Journal of Medicine. 1997 ; Vol. 336, No. 10. pp. 677-682.
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Gabriel, S, Woods, JE, O'Fallon, WM, Beard, CM, Kurland, LT & Melton, LJ 1997, 'Complications leading to surgery after breast implantation', New England Journal of Medicine, vol. 336, no. 10, pp. 677-682. https://doi.org/10.1056/NEJM199703063361001

Complications leading to surgery after breast implantation. / Gabriel, Sherine; Woods, John E.; O'Fallon, W. Michael; Beard, C. Mary; Kurland, Leonard T.; Melton, L. Joseph.

In: New England Journal of Medicine, Vol. 336, No. 10, 06.03.1997, p. 677-682.

Research output: Contribution to journalArticle

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AU - Gabriel, Sherine

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N2 - Background: Local complications that require additional surgical procedures are an important problem for women with breast implants. Methods: We studied 749 women who lived in Olmsted County, Minnesota, and received a first breast implant at the Mayo Clinic between 1964 and 1991. We identified complications that occurred after the initial procedure and after any subsequent implantation. A complication was defined as a surgical procedure performed for any of the following reasons: capsular contracture; rupture of the implant; hematoma or bleeding; infection or seroma of the wound; chronic pain; extrusion, leakage, or sweating of the implant; necrosis of the nipple, areola, or flap; malfunction of the filler port of a tissue expander; and wound dehiscence. Results: During follow-up (mean, 7.8 years; range, 0 to 25.8), 208 (27.8 percent) of the women underwent 450 additional implant- related surgical procedures. Ninety-one (20.2 percent) were anticipated, staged procedures or were done because the patient requested a size change or aesthetic improvement, and 359 procedures (79.8 percent) had at least one clinical indication (thus constituting a complication). Complications occurred in 178 (23.8 percent) of the 749 women and involved 274 (18.8 percent) of the 1454 breasts with implants and 321 (18.8 percent) of the 1703 implants. The most frequent problem was capsular contraction (131 women), followed by implant rupture (43 [5.7 percent]), hematoma (43), and wound infection (19). The rate of complications was significantly lower (P<0.001) among women with cosmetic implants (6.5 percent at one year, 12 percent at five years) than among those who received implants after mastectomy for breast cancer (21.8 percent at one year, 34 percent at five years) or prophylactic mastectomy (17.3 percent at one year, 30.4 percent at five years). Conclusions: Women who have had breast implantation frequently experience local complications during the subsequent five years. Complications were significantly less frequent among patients who received implants for cosmetic reasons than among those who received implants after mastectomy for cancer or for cancer prophylaxis.

AB - Background: Local complications that require additional surgical procedures are an important problem for women with breast implants. Methods: We studied 749 women who lived in Olmsted County, Minnesota, and received a first breast implant at the Mayo Clinic between 1964 and 1991. We identified complications that occurred after the initial procedure and after any subsequent implantation. A complication was defined as a surgical procedure performed for any of the following reasons: capsular contracture; rupture of the implant; hematoma or bleeding; infection or seroma of the wound; chronic pain; extrusion, leakage, or sweating of the implant; necrosis of the nipple, areola, or flap; malfunction of the filler port of a tissue expander; and wound dehiscence. Results: During follow-up (mean, 7.8 years; range, 0 to 25.8), 208 (27.8 percent) of the women underwent 450 additional implant- related surgical procedures. Ninety-one (20.2 percent) were anticipated, staged procedures or were done because the patient requested a size change or aesthetic improvement, and 359 procedures (79.8 percent) had at least one clinical indication (thus constituting a complication). Complications occurred in 178 (23.8 percent) of the 749 women and involved 274 (18.8 percent) of the 1454 breasts with implants and 321 (18.8 percent) of the 1703 implants. The most frequent problem was capsular contraction (131 women), followed by implant rupture (43 [5.7 percent]), hematoma (43), and wound infection (19). The rate of complications was significantly lower (P<0.001) among women with cosmetic implants (6.5 percent at one year, 12 percent at five years) than among those who received implants after mastectomy for breast cancer (21.8 percent at one year, 34 percent at five years) or prophylactic mastectomy (17.3 percent at one year, 30.4 percent at five years). Conclusions: Women who have had breast implantation frequently experience local complications during the subsequent five years. Complications were significantly less frequent among patients who received implants for cosmetic reasons than among those who received implants after mastectomy for cancer or for cancer prophylaxis.

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