@inproceedings{9d48f1589e5640cdac51ce7ebc38c7d1,
title = "Computer assisted receptor mapping approach to the design of anti-AIDS agents directed at HIV reverse transcriptase",
abstract = "A number of nucleoside analogs have been successfully used as effective inhibitors directed at Reverse Transcriptase (RT). However, the emergence of viral strains which exhibit resistance to these analogs as well as cellular toxicity concerns have mandated the search for new and highly selective inhibitors. With this goal in mind the authors have taken a pharmacophoric approach to the identification of a substrate/inhibitor binding site on HIV-1 RT. Molecular modeling studies were conducted on a personal Iris workstation from Silicon Graphics running under UNIX. The SYBYL molecular modeling software version 5.5 was used for the representation and manipulation of the structures used in this study.",
author = "Fisher, {Mark A.} and Yadav, {Prem N.S.} and Janardan Yadav and Swamy Laxminarayan and David Kristol and Mukund Modak",
year = "1993",
language = "American English",
isbn = "0780309251",
series = "Bioengineering, Proceedings of the Northeast Conference",
publisher = "Publ by IEEE",
pages = "162--163",
booktitle = "1993 IEEE 19th Annual Northeasrt Bioengineering Conference",
note = "Proceedings of the 1993 IEEE 19th Annual Northeast Bioengineering Conference ; Conference date: 18-03-1993 Through 19-03-1993",
}