Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene

Yong Yang; Isaac Edery

doi:10.1016/j.cub.2019.04.039

Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene

Yong Yang, Isaac Edery

Rutgers, The State University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Yong and Edery identify an anti-siesta gene in Drosophila, hereinafter termed daywake, that is regulated in an unprecedented manner by splicing of the cold-enhanced dmpi8 intron from the reverse-oriented and slightly overlapping period clock gene. The dmpi8-dyw unit stimulates midday activity on days that carry less risks from heat exposure.

Original language	American English
Pages (from-to)	1728-1734.e4
Journal	Current Biology
Volume	29
Issue number	10
DOIs	https://doi.org/10.1016/j.cub.2019.04.039
State	Published - May 20 2019

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

Keywords

0.9 gene
Daywake
Drosophila
dmpi8 intron
juvenile hormone-binding protein
midday siesta
period clock gene
pre-mRNA splicing
sleep-wake behavior

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10.1016/j.cub.2019.04.039

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title = "Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene",

abstract = "Yong and Edery identify an anti-siesta gene in Drosophila, hereinafter termed daywake, that is regulated in an unprecedented manner by splicing of the cold-enhanced dmpi8 intron from the reverse-oriented and slightly overlapping period clock gene. The dmpi8-dyw unit stimulates midday activity on days that carry less risks from heat exposure.",

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doi = "10.1016/j.cub.2019.04.039",

language = "American English",

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AU - Yang, Yong

AU - Edery, Isaac

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Y1 - 2019/5/20

N2 - Yong and Edery identify an anti-siesta gene in Drosophila, hereinafter termed daywake, that is regulated in an unprecedented manner by splicing of the cold-enhanced dmpi8 intron from the reverse-oriented and slightly overlapping period clock gene. The dmpi8-dyw unit stimulates midday activity on days that carry less risks from heat exposure.

AB - Yong and Edery identify an anti-siesta gene in Drosophila, hereinafter termed daywake, that is regulated in an unprecedented manner by splicing of the cold-enhanced dmpi8 intron from the reverse-oriented and slightly overlapping period clock gene. The dmpi8-dyw unit stimulates midday activity on days that carry less risks from heat exposure.

KW - 0.9 gene

KW - Daywake

KW - Drosophila

KW - dmpi8 intron

KW - juvenile hormone-binding protein

KW - midday siesta

KW - period clock gene

KW - pre-mRNA splicing

KW - sleep-wake behavior

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JO - Current Biology

JF - Current Biology

IS - 10

ER -

Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene

Abstract

ASJC Scopus subject areas

Keywords

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