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Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice
Gareth R. Howell
, Ileana Soto
, Margaret Ryan
, Leah C. Graham
, Richard S. Smith
, Simon W.M. John
Research output
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Contribution to journal
›
Article
›
peer-review
56
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Scopus citations
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Keyphrases
Glaucoma
100%
Complement Component 5
100%
Complement Cascade
57%
Retina
28%
Retinal Ganglion Cells
28%
Membrane Attack Complex
28%
Neurodegenerative Diseases
14%
Mouse Model
14%
C57BL
14%
Downstream Process
14%
Disease Severity
14%
Soma
14%
Immunofluorescence
14%
Inflammatory Process
14%
Blindness
14%
Axonal Injury
14%
Age-related Neurodegeneration
14%
Ocular Examination
14%
Optic Nerve Head
14%
Functional Components
14%
Optic Nerve
14%
Human Glaucoma
14%
5 Gene
14%
Retinal Ganglion Cell Degeneration
14%
Severe Glaucoma
14%
Optic Nerve Damage
14%
Glaucoma Severity
14%
Hemolytic Complement
14%
IOP Measurement
14%
Pharmacology, Toxicology and Pharmaceutical Science
Glaucoma
100%
DBA 2 Mouse
100%
Complement Component C5
100%
Complement Membrane Attack Complex
20%
Diseases
20%
Degenerative Disease
10%
Inflammation
10%
Mouse Model
10%
Prevalence
10%
Disease Severity
10%
Nerve Cell Degeneration
10%
Carisoprodol
10%
Axonal Injury
10%
Optic Nerve Lesion
10%
Neuroscience
Glaucoma
100%
Complement Component C5
100%
Retinal Ganglion Cell
30%
Optic Nerve
30%
Complement Membrane Attack Complex
20%
Neurodegenerative Disorder
10%
Soma
10%
Immunofluorescence
10%
Nerve Cell Degeneration
10%
Age-Related Neurodegenerative Disorder
10%
Nerve Injury
10%
Carisoprodol
10%