Detection of oligonucleotides electronically at the nanoscale

Rahim Esfandyarpour, Mehdi Javanmard, Zahra Koochak, James S. Harris, Ronald W. Davis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Here we present an ultrasensitive and label-free biosensor referred to as the nanoneedles biosensor. The nanoneedle biosensor shows promise to overcome some of the limitations of existence biosensors. The nanoneedle biosensor has the advantages of being a real-time, label-free and direct electrical detection platform. This novel electrical biosensor is capable of high sensitivity detection, by measuring the change in ionic current and impedance modulation, due to the presence or interaction of biomolecules such as proteins or nucleic acids. In this paper we discuss fabrication of our sensors first and then we talk about the study of electrical properties of DNA at the nanoscale.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013
Pages115-118
Number of pages4
StatePublished - 2013
Externally publishedYes
EventNanotechnology 2013: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013 - Washington, DC, United States
Duration: May 12 2013May 16 2013

Publication series

NameTechnical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013
Volume2

Other

OtherNanotechnology 2013: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013
Country/TerritoryUnited States
CityWashington, DC
Period5/12/135/16/13

All Science Journal Classification (ASJC) codes

  • Biotechnology

Keywords

  • Biosensors
  • DNA
  • Impedance biosensor
  • Label free
  • Nanotechnology

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