Does Cardiac Contractility Modulation Therapy Reduce Atrial Fibrillation Burden?

Jae Wook Shin, Rami Atoot, Marissa Heyer, Sameer Jamal

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac contractility modulation (CCM) is an implantable technology approved by the U.S. Food and Drug Administration and intended for heart failure patients without a cardiac resynchronization therapy indication. CCM leads to reduced heart failure hospitalizations and improvements in exercise tolerance and quality of life. There are a lack of data examining the impact of CCM therapy on atrial fibrillation (AF) burden. We report the case of a 65-year-old man with a history of paroxysmal AF, hypertension, hyperlipidemia, and carotid artery stenosis who presented with newly diagnosed ischemic cardiomyopathy with a left ventricular ejection fraction (LVEF) of 20%-25%. He underwent coronary artery bypass graft surgery for triple vessel disease with an improvement in LVEF to 40% after 4 months of guideline-directed medical therapy. Due to clinical heart failure and paroxysms of AF, he underwent CCM device and implantable loop recorder (ILR) implantation. His LVEF improved to 60%, and the ILR showed no AF. We postulate multiple mechanisms to explain the negligible burden of AF.

Original languageEnglish
Pages (from-to)5202-5204
Number of pages3
JournalJournal of Innovations in Cardiac Rhythm Management
Volume13
Issue number10
DOIs
StatePublished - Oct 2022

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Keywords

  • Atrial fibrillation
  • cardiac contractility modulation

Fingerprint

Dive into the research topics of 'Does Cardiac Contractility Modulation Therapy Reduce Atrial Fibrillation Burden?'. Together they form a unique fingerprint.

Cite this